Gallbladder cancer differential diagnosis: Difference between revisions

Latest revision as of 21:59, 8 February 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

Gallbladder cancer must be differentiated from hepatocellular carcinoma liver hemangioma, Liver abscess, cirrhosis, inflammatory lesions, cholangiocarcinoma, pancreatic carcinoma, focal nodular hyperplasia.

Differentiatiating Gallbladder cancer from other Diseases

Gallbladder cancer must be differentiated from other diseases that causes right upper quadrant pain include followings:^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]^[9]^[10]^[11]^[12]^[13]^[14]^[15]^[16]^[17]^[18]^[19]^[20]^[21]

	Abdominal Pain	Fever	Rigors and chills	Nausea or vomiting	Jaundice	Constipation	Diarrhea	Weight loss	GI bleeding	Hypo- tension	Guarding	Rebound Tenderness	Bowel sounds	Lab Findings	Imaging
Disease	Clinical manifestations													Diagnosis		Comments
	Symptoms									Signs				Diagnosis
Hepatocellular carcinoma/Metastasis	RUQ	+	−	−	+	−	−	+	−	−	−	−	Normal Hyperactive if obstruction present	High levels of AFP in serum Abnormal liver function tests	US CT Liver biopsy	Other symptoms: Splenomegaly Variceal bleeding Ascites Spider nevi Asterixis
Cholangiocarcinoma	Epigastric	−	−	±	±	−	+	+	−	−	−	−	N	Increased amylase / lipase Increased stool fat content Pancreatic function test	CT scan Calcification Pseudocyst Dilation of main pancreatic duct	Predisposes to pancreatic cancer
Pancreatic carcinoma	Epigastric	−	−	+	+	−	+	+	−	−	−	−	N	↑ Alkaline phosphatase ↑ serum bilirubin ↑ gamma-glutamyl transpeptidase ↑ CA 19-9	MDCT with PET/CT MRI	Skin manifestations may include: Bullous pemphigoid Cicatricial pemphigoid Migratory superficial thrombophlebitis (classic Trousseau's syndrome) Pancreatic panniculitis
Focal nodular hyperplasia	Diffuse	±	−	−	±	−	+	+	+	−	−	−	Normal or hyperactive	Anti-neutrophil cytoplasmic antibody (P-ANCA) in Ulcerative colitis Anti saccharomyces cerevisiae antibodies (ASCA) in Crohn's disease	String sign on abdominal x-ray in Crohn's disease	Extra intestinal findings: Uveitis Arthritis
Disease	Abdominal Pain	Fever	Rigors and chills	Nausea or vomiting	Jaundice	Constipation	Diarrhea	Weight loss	GI bleeding	Hypo- tension	Guarding	Rebound Tenderness	Bowel sounds	Lab Findings	Imaging	Comments
Gallbladder cancer	Diffuse	±	−	−	±	−	+	+	−	±	−	−	N	Thrombocytopenia Hypoalbuminemia Small intestinal biopsy for Tropheryma whipplei	Endoscopy is used to confirm diagnosis. Images used to find complications Chest and joint x-ray CT MRI Echocardiography	Extra intestinal findings: Uveitis Endocarditis Encephalitis Dementia Hepatosplenomegaly Arthritis Ascites
Liver hemangioma	RUQ	+	−	+	+	−	Positive in Hep A and E	+	−	Positive in fulminant hepatitis	Positive in acute	+	N	Abnormal LFTs Viral serology	US	Hep A and E have fecal-oral route of transmission Hep B and C transmits via blood transfusion and sexual contact.
Liver abscess	RUQ	+	+	+	+	−	±	+	−	+	+	±	Normal or hypoactive	CBC Blood cultures Abnormal liver function tests	US CT
Cirrhosis	RUQ	−	−	−	+	−	−	+	+	+	−	−	N	Hypoalbuminemia Prolonged PT Abnormal LFTs Hyponatremia Thrombocytopenia	US Nodular, shrunken liver Ascites	Stigmata of liver disease Cruveilhier- Baumgarten murmur
Inflammatory lesions	RUQ	−	−	−	+	−	−	+	+	+	−	−	N	Hypoalbuminemia Prolonged PT Abnormal LFTs Hyponatremia Thrombocytopenia	US Nodular, shrunken liver Ascites	Stigmata of liver disease Cruveilhier- Baumgarten murmur

Abbreviations:RUQ= Right upper quadrant of the abdomen, LUQ= Left upper quadrant, LLQ= Left lower quadrant, RLQ= Right lower quadrant, LFT= Liver function test, SIRS= Systemic inflammatory response syndrome, ERCP= Endoscopic retrograde cholangiopancreatography, IV= Intravenous, N= Normal, AMA= Anti mitochondrial antibodies, LDH= Lactate dehydrogenase, GI= Gastrointestinal, CXR= Chest X ray, IgA= Immunoglobulin A, IgG= Immunoglobulin G, IgM= Immunoglobulin M, CT= Computed tomography, PMN= Polymorphonuclear cells, ESR= Erythrocyte sedimentation rate, CRP= C-reactive protein, TS= Transferrin saturation, SF= Serum Ferritin, SMA= Superior mesenteric artery, SMV= Superior mesenteric vein, ECG= Electrocardiogram

References

↑ Kim TK, Lee E, Jang HJ (2015). "Imaging findings of mimickers of hepatocellular carcinoma". Clin Mol Hepatol. 21 (4): 326–43. doi:10.3350/cmh.2015.21.4.326. PMC 4712159. PMID 26770920.
↑ Ferrell, Linda (2000). "Liver Pathology: Cirrhosis, Hepatitis and Primary Liver Tumors. Update and Diagnostic Problems". Modern Pathology. 13 (6): 679–704. doi:10.1038/modpathol.3880119. ISSN 0893-3952.
↑ Kim, Tae Kyoung; Lee, Eunchae; Jang, Hyun-Jung (2015). "Imaging findings of mimickers of hepatocellular carcinoma". Clinical and Molecular Hepatology. 21 (4): 326. doi:10.3350/cmh.2015.21.4.326. ISSN 2287-2728.
↑ Kim, Tae Kyoung; Lee, Eunchae; Jang, Hyun-Jung (2015). "Imaging findings of mimickers of hepatocellular carcinoma". Clinical and Molecular Hepatology. 21 (4): 326. doi:10.3350/cmh.2015.21.4.326. ISSN 2287-2728.
↑ Alturkistany, Samira; Jang, Hyun-Jung; Yu, Hojun; Lee, Kyoung Ho; Kim, Tae Kyoung (2011). "Fading hepatic hemangiomas on multiphasic CT". Abdominal Radiology. 37 (5): 775–780. doi:10.1007/s00261-011-9826-6. ISSN 2366-004X.
↑ Heiken, Jay P. (2007). "Distinguishing benign from malignant liver tumours". Cancer Imaging. 7 (Special Issue A): S1–S14. doi:10.1102/1470-7330.2007.9084. ISSN 1470-7330.
↑ Tamada T, Ito K, Yamamoto A, Sone T, Kanki A, Tanaka F, Higashi H (2011). "Hepatic hemangiomas: evaluation of enhancement patterns at dynamic MRI with gadoxetate disodium". AJR Am J Roentgenol. 196 (4): 824–30. doi:10.2214/AJR.10.5113. PMID 21427331.
↑ Bhayana, Deepak; Kim, Tae Kyoung; Jang, Hyun-Jung; Burns, Peter N.; Wilson, Stephanie R. (2010). "Hypervascular Liver Masses on Contrast-Enhanced Ultrasound: The Importance of Washout". American Journal of Roentgenology. 194 (4): 977–983. doi:10.2214/AJR.09.3375. ISSN 0361-803X.
↑ Bhayana, Deepak; Kim, Tae Kyoung; Jang, Hyun-Jung; Burns, Peter N.; Wilson, Stephanie R. (2010). "Hypervascular Liver Masses on Contrast-Enhanced Ultrasound: The Importance of Washout". American Journal of Roentgenology. 194 (4): 977–983. doi:10.2214/AJR.09.3375. ISSN 0361-803X.
↑ Kim, Tae Kyoung; Lee, Kyoung Ho; Jang, Hyun–Jung; Haider, Masoom A.; Jacks, Lindsay M.; Menezes, Ravi J.; Park, Seong Ho; Yazdi, Leyla; Sherman, Morris; Khalili, Korosh (2011). "Analysis of Gadobenate Dimeglumine–enhanced MR Findings for Characterizing Small (1–2-cm) Hepatic Nodules in Patients at High Risk for Hepatocellular Carcinoma". Radiology. 259 (3): 730–738. doi:10.1148/radiol.11101549. ISSN 0033-8419.
↑ Kim JH, Kim TK, Kim BS, Eun HW, Kim PN, Lee MG, Ha HK (2002). "Enhancement of hepatic hemangiomas with levovist on coded harmonic angiographic ultrasonography". J Ultrasound Med. 21 (2): 141–8. PMID 11833870.
↑ Brannigan, Margot; Burns, Peter N.; Wilson, Stephanie R. (2004). "Blood Flow Patterns in Focal Liver Lesions at Microbubble-enhanced US". RadioGraphics. 24 (4): 921–935. doi:10.1148/rg.244035158. ISSN 0271-5333.
↑ Menias, Christine O.; Surabhi, Venkateswar R.; Prasad, Srinivasa R.; Wang, Hanlin L.; Narra, Vamsi R.; Chintapalli, Kedar N. (2008). "Mimics of Cholangiocarcinoma: Spectrum of Disease". RadioGraphics. 28 (4): 1115–1129. doi:10.1148/rg.284075148. ISSN 0271-5333.
↑ Syed MA, Kim TK, Jang HJ (2007). "Portal and hepatic vein thrombosis in liver abscess: CT findings". Eur J Radiol. 61 (3): 513–9. doi:10.1016/j.ejrad.2006.11.022. PMID 17161932.
↑ Kim TK, Jang HJ, Wilson SR (2006). "Benign liver masses: imaging with microbubble contrast agents". Ultrasound Q. 22 (1): 31–9. PMID 16641791.
↑ Kim, Kyoung Won; Choi, Byung Ihn; Park, Seong Ho; Kim, Ah Young; Koh, Young Hwan; Lee, Hyun Ju; Han, Joon Koo (2004). "Pyogenic hepatic abscesses: distinctive features from hypovascular hepatic malignancies on contrast-enhanced ultrasound with SH U 508A; early experience". Ultrasound in Medicine & Biology. 30 (6): 725–733. doi:10.1016/j.ultrasmedbio.2004.03.006. ISSN 0301-5629.
↑ Liu GJ, Lu MD, Xie XY, Xu HX, Xu ZF, Zheng YL, Liang JY, Wang W (2008). "Real-time contrast-enhanced ultrasound imaging of infected focal liver lesions". J Ultrasound Med. 27 (4): 657–66. PMID 18359914.
↑ Wilson, Stephanie R.; Kim, Tae Kyoung; Jang, Hyun-Jung; Burns, Peter N. (2007). "Enhancement Patterns of Focal Liver Masses: Discordance Between Contrast-Enhanced Sonography and Contrast-Enhanced CT and MRI". American Journal of Roentgenology. 189 (1): W7–W12. doi:10.2214/AJR.06.1060. ISSN 0361-803X.
↑ Guo, Le-Hang; Xu, Hui-Xiong (2015). "Contrast-Enhanced Ultrasound in the Diagnosis of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma: Controversy over the ASSLD Guideline". BioMed Research International. 2015: 1–5. doi:10.1155/2015/349172. ISSN 2314-6133.
↑ Choi BI, Kim TK, Han JK (1998). "MRI of clonorchiasis and cholangiocarcinoma". J Magn Reson Imaging. 8 (2): 359–66. PMID 9562062.
↑ Kim, T K; Choi, B I; Han, J K; Jang, H J; Cho, S G; Han, M C (1997). "Peripheral cholangiocarcinoma of the liver: two-phase spiral CT findings". Radiology. 204 (2): 539–543. doi:10.1148/radiology.204.2.9240550. ISSN 0033-8419.

Template:WikiDoc Sources

[pmid26770920-1] Kim TK, Lee E, Jang HJ (2015). "Imaging findings of mimickers of hepatocellular carcinoma". Clin Mol Hepatol. 21 (4): 326–43. doi:10.3350/cmh.2015.21.4.326. PMC 4712159. PMID 26770920.

[Ferrell2000-2] Ferrell, Linda (2000). "Liver Pathology: Cirrhosis, Hepatitis and Primary Liver Tumors. Update and Diagnostic Problems". Modern Pathology. 13 (6): 679–704. doi:10.1038/modpathol.3880119. ISSN 0893-3952.

[KimLee2015-3] Kim, Tae Kyoung; Lee, Eunchae; Jang, Hyun-Jung (2015). "Imaging findings of mimickers of hepatocellular carcinoma". Clinical and Molecular Hepatology. 21 (4): 326. doi:10.3350/cmh.2015.21.4.326. ISSN 2287-2728.

[KimLee20152-4] Kim, Tae Kyoung; Lee, Eunchae; Jang, Hyun-Jung (2015). "Imaging findings of mimickers of hepatocellular carcinoma". Clinical and Molecular Hepatology. 21 (4): 326. doi:10.3350/cmh.2015.21.4.326. ISSN 2287-2728.

[AlturkistanyJang2011-5] Alturkistany, Samira; Jang, Hyun-Jung; Yu, Hojun; Lee, Kyoung Ho; Kim, Tae Kyoung (2011). "Fading hepatic hemangiomas on multiphasic CT". Abdominal Radiology. 37 (5): 775–780. doi:10.1007/s00261-011-9826-6. ISSN 2366-004X.

[Heiken2007-6] Heiken, Jay P. (2007). "Distinguishing benign from malignant liver tumours". Cancer Imaging. 7 (Special Issue A): S1–S14. doi:10.1102/1470-7330.2007.9084. ISSN 1470-7330.

[pmid21427331-7] Tamada T, Ito K, Yamamoto A, Sone T, Kanki A, Tanaka F, Higashi H (2011). "Hepatic hemangiomas: evaluation of enhancement patterns at dynamic MRI with gadoxetate disodium". AJR Am J Roentgenol. 196 (4): 824–30. doi:10.2214/AJR.10.5113. PMID 21427331.

[BhayanaKim2010-8] Bhayana, Deepak; Kim, Tae Kyoung; Jang, Hyun-Jung; Burns, Peter N.; Wilson, Stephanie R. (2010). "Hypervascular Liver Masses on Contrast-Enhanced Ultrasound: The Importance of Washout". American Journal of Roentgenology. 194 (4): 977–983. doi:10.2214/AJR.09.3375. ISSN 0361-803X.

[BhayanaKim20102-9] Bhayana, Deepak; Kim, Tae Kyoung; Jang, Hyun-Jung; Burns, Peter N.; Wilson, Stephanie R. (2010). "Hypervascular Liver Masses on Contrast-Enhanced Ultrasound: The Importance of Washout". American Journal of Roentgenology. 194 (4): 977–983. doi:10.2214/AJR.09.3375. ISSN 0361-803X.

[KimLee2011-10] Kim, Tae Kyoung; Lee, Kyoung Ho; Jang, Hyun–Jung; Haider, Masoom A.; Jacks, Lindsay M.; Menezes, Ravi J.; Park, Seong Ho; Yazdi, Leyla; Sherman, Morris; Khalili, Korosh (2011). "Analysis of Gadobenate Dimeglumine–enhanced MR Findings for Characterizing Small (1–2-cm) Hepatic Nodules in Patients at High Risk for Hepatocellular Carcinoma". Radiology. 259 (3): 730–738. doi:10.1148/radiol.11101549. ISSN 0033-8419.

[pmid11833870-11] Kim JH, Kim TK, Kim BS, Eun HW, Kim PN, Lee MG, Ha HK (2002). "Enhancement of hepatic hemangiomas with levovist on coded harmonic angiographic ultrasonography". J Ultrasound Med. 21 (2): 141–8. PMID 11833870.

[BranniganBurns2004-12] Brannigan, Margot; Burns, Peter N.; Wilson, Stephanie R. (2004). "Blood Flow Patterns in Focal Liver Lesions at Microbubble-enhanced US". RadioGraphics. 24 (4): 921–935. doi:10.1148/rg.244035158. ISSN 0271-5333.

[MeniasSurabhi2008-13] Menias, Christine O.; Surabhi, Venkateswar R.; Prasad, Srinivasa R.; Wang, Hanlin L.; Narra, Vamsi R.; Chintapalli, Kedar N. (2008). "Mimics of Cholangiocarcinoma: Spectrum of Disease". RadioGraphics. 28 (4): 1115–1129. doi:10.1148/rg.284075148. ISSN 0271-5333.

[pmid17161932-14] Syed MA, Kim TK, Jang HJ (2007). "Portal and hepatic vein thrombosis in liver abscess: CT findings". Eur J Radiol. 61 (3): 513–9. doi:10.1016/j.ejrad.2006.11.022. PMID 17161932.

[pmid16641791-15] Kim TK, Jang HJ, Wilson SR (2006). "Benign liver masses: imaging with microbubble contrast agents". Ultrasound Q. 22 (1): 31–9. PMID 16641791.

[KimChoi2004-16] Kim, Kyoung Won; Choi, Byung Ihn; Park, Seong Ho; Kim, Ah Young; Koh, Young Hwan; Lee, Hyun Ju; Han, Joon Koo (2004). "Pyogenic hepatic abscesses: distinctive features from hypovascular hepatic malignancies on contrast-enhanced ultrasound with SH U 508A; early experience". Ultrasound in Medicine & Biology. 30 (6): 725–733. doi:10.1016/j.ultrasmedbio.2004.03.006. ISSN 0301-5629.

[pmid18359914-17] Liu GJ, Lu MD, Xie XY, Xu HX, Xu ZF, Zheng YL, Liang JY, Wang W (2008). "Real-time contrast-enhanced ultrasound imaging of infected focal liver lesions". J Ultrasound Med. 27 (4): 657–66. PMID 18359914.

[WilsonKim2007-18] Wilson, Stephanie R.; Kim, Tae Kyoung; Jang, Hyun-Jung; Burns, Peter N. (2007). "Enhancement Patterns of Focal Liver Masses: Discordance Between Contrast-Enhanced Sonography and Contrast-Enhanced CT and MRI". American Journal of Roentgenology. 189 (1): W7–W12. doi:10.2214/AJR.06.1060. ISSN 0361-803X.

[GuoXu2015-19] Guo, Le-Hang; Xu, Hui-Xiong (2015). "Contrast-Enhanced Ultrasound in the Diagnosis of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma: Controversy over the ASSLD Guideline". BioMed Research International. 2015: 1–5. doi:10.1155/2015/349172. ISSN 2314-6133.

[pmid9562062-20] Choi BI, Kim TK, Han JK (1998). "MRI of clonorchiasis and cholangiocarcinoma". J Magn Reson Imaging. 8 (2): 359–66. PMID 9562062.

[KimChoi1997-21] Kim, T K; Choi, B I; Han, J K; Jang, H J; Cho, S G; Han, M C (1997). "Peripheral cholangiocarcinoma of the liver: two-phase spiral CT findings". Radiology. 204 (2): 539–543. doi:10.1148/radiology.204.2.9240550. ISSN 0033-8419.

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@@ Line 1: / Line 1: @@
 __NOTOC__
-{{Gallbladder cancer}}
+[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Gallbladder_cancer]]
+{{CMG}}; {{AE}}{{VKG}}
-Please help WikiDoc by adding content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
-{{CMG}}
 ==Overview==
+Gallbladder cancer must be differentiated from hepatocellular carcinoma [[liver hemangioma|liver hemangioma,]] [[Liver abscess]], [[cirrhosis]], [[Inflammation|inflammatory]] [[Lesion|lesions]], [[Cholangiocarcinoma|cholangiocarcinoma,]] [[Pancreatic carcinoma|pancreatic carcinoma,]] [[focal nodular hyperplasia]].
 ==Differentiatiating Gallbladder cancer from other Diseases==
+Gallbladder cancer must be differentiated from other diseases that causes right upper quadrant pain include followings:<ref name="pmid26770920">{{cite journal |vauthors=Kim TK, Lee E, Jang HJ |title=Imaging findings of mimickers of hepatocellular carcinoma |journal=Clin Mol Hepatol |volume=21 |issue=4 |pages=326–43 |year=2015 |pmid=26770920 |pmc=4712159 |doi=10.3350/cmh.2015.21.4.326 |url=}}</ref><ref name="Ferrell2000">{{cite journal|last1=Ferrell|first1=Linda|title=Liver Pathology: Cirrhosis, Hepatitis and Primary Liver Tumors. Update and Diagnostic Problems|journal=Modern Pathology|volume=13|issue=6|year=2000|pages=679–704|issn=0893-3952|doi=10.1038/modpathol.3880119}}</ref><ref name="KimLee2015">{{cite journal|last1=Kim|first1=Tae Kyoung|last2=Lee|first2=Eunchae|last3=Jang|first3=Hyun-Jung|title=Imaging findings of mimickers of hepatocellular carcinoma|journal=Clinical and Molecular Hepatology|volume=21|issue=4|year=2015|pages=326|issn=2287-2728|doi=10.3350/cmh.2015.21.4.326}}</ref><ref name="KimLee20152">{{cite journal|last1=Kim|first1=Tae Kyoung|last2=Lee|first2=Eunchae|last3=Jang|first3=Hyun-Jung|title=Imaging findings of mimickers of hepatocellular carcinoma|journal=Clinical and Molecular Hepatology|volume=21|issue=4|year=2015|pages=326|issn=2287-2728|doi=10.3350/cmh.2015.21.4.326}}</ref><ref name="AlturkistanyJang2011">{{cite journal|last1=Alturkistany|first1=Samira|last2=Jang|first2=Hyun-Jung|last3=Yu|first3=Hojun|last4=Lee|first4=Kyoung Ho|last5=Kim|first5=Tae Kyoung|title=Fading hepatic hemangiomas on multiphasic CT|journal=Abdominal Radiology|volume=37|issue=5|year=2011|pages=775–780|issn=2366-004X|doi=10.1007/s00261-011-9826-6}}</ref><ref name="Heiken2007">{{cite journal|last1=Heiken|first1=Jay P.|title=Distinguishing benign from malignant liver tumours|journal=Cancer Imaging|volume=7|issue=Special Issue A|year=2007|pages=S1–S14|issn=1470-7330|doi=10.1102/1470-7330.2007.9084}}</ref><ref name="pmid21427331">{{cite journal |vauthors=Tamada T, Ito K, Yamamoto A, Sone T, Kanki A, Tanaka F, Higashi H |title=Hepatic hemangiomas: evaluation of enhancement patterns at dynamic MRI with gadoxetate disodium |journal=AJR Am J Roentgenol |volume=196 |issue=4 |pages=824–30 |year=2011 |pmid=21427331 |doi=10.2214/AJR.10.5113 |url=}}</ref><ref name="BhayanaKim2010">{{cite journal|last1=Bhayana|first1=Deepak|last2=Kim|first2=Tae Kyoung|last3=Jang|first3=Hyun-Jung|last4=Burns|first4=Peter N.|last5=Wilson|first5=Stephanie R.|title=Hypervascular Liver Masses on Contrast-Enhanced Ultrasound: The Importance of Washout|journal=American Journal of Roentgenology|volume=194|issue=4|year=2010|pages=977–983|issn=0361-803X|doi=10.2214/AJR.09.3375}}</ref><ref name="BhayanaKim20102">{{cite journal|last1=Bhayana|first1=Deepak|last2=Kim|first2=Tae Kyoung|last3=Jang|first3=Hyun-Jung|last4=Burns|first4=Peter N.|last5=Wilson|first5=Stephanie R.|title=Hypervascular Liver Masses on Contrast-Enhanced Ultrasound: The Importance of Washout|journal=American Journal of Roentgenology|volume=194|issue=4|year=2010|pages=977–983|issn=0361-803X|doi=10.2214/AJR.09.3375}}</ref><ref name="KimLee2011">{{cite journal|last1=Kim|first1=Tae Kyoung|last2=Lee|first2=Kyoung Ho|last3=Jang|first3=Hyun–Jung|last4=Haider|first4=Masoom A.|last5=Jacks|first5=Lindsay M.|last6=Menezes|first6=Ravi J.|last7=Park|first7=Seong Ho|last8=Yazdi|first8=Leyla|last9=Sherman|first9=Morris|last10=Khalili|first10=Korosh|title=Analysis of Gadobenate Dimeglumine–enhanced MR Findings for Characterizing Small (1–2-cm) Hepatic Nodules in Patients at High Risk for Hepatocellular Carcinoma|journal=Radiology|volume=259|issue=3|year=2011|pages=730–738|issn=0033-8419|doi=10.1148/radiol.11101549}}</ref><ref name="pmid11833870">{{cite journal |vauthors=Kim JH, Kim TK, Kim BS, Eun HW, Kim PN, Lee MG, Ha HK |title=Enhancement of hepatic hemangiomas with levovist on coded harmonic angiographic ultrasonography |journal=J Ultrasound Med |volume=21 |issue=2 |pages=141–8 |year=2002 |pmid=11833870 |doi= |url=}}</ref><ref name="BranniganBurns2004">{{cite journal|last1=Brannigan|first1=Margot|last2=Burns|first2=Peter N.|last3=Wilson|first3=Stephanie R.|title=Blood Flow Patterns in Focal Liver Lesions at Microbubble-enhanced US|journal=RadioGraphics|volume=24|issue=4|year=2004|pages=921–935|issn=0271-5333|doi=10.1148/rg.244035158}}</ref><ref name="MeniasSurabhi2008">{{cite journal|last1=Menias|first1=Christine O.|last2=Surabhi|first2=Venkateswar R.|last3=Prasad|first3=Srinivasa R.|last4=Wang|first4=Hanlin L.|last5=Narra|first5=Vamsi R.|last6=Chintapalli|first6=Kedar N.|title=Mimics of Cholangiocarcinoma: Spectrum of Disease|journal=RadioGraphics|volume=28|issue=4|year=2008|pages=1115–1129|issn=0271-5333|doi=10.1148/rg.284075148}}</ref><ref name="pmid17161932">{{cite journal |vauthors=Syed MA, Kim TK, Jang HJ |title=Portal and hepatic vein thrombosis in liver abscess: CT findings |journal=Eur J Radiol |volume=61 |issue=3 |pages=513–9 |year=2007 |pmid=17161932 |doi=10.1016/j.ejrad.2006.11.022 |url=}}</ref><ref name="pmid16641791">{{cite journal |vauthors=Kim TK, Jang HJ, Wilson SR |title=Benign liver masses: imaging with microbubble contrast agents |journal=Ultrasound Q |volume=22 |issue=1 |pages=31–9 |year=2006 |pmid=16641791 |doi= |url=}}</ref><ref name="KimChoi2004">{{cite journal|last1=Kim|first1=Kyoung Won|last2=Choi|first2=Byung Ihn|last3=Park|first3=Seong Ho|last4=Kim|first4=Ah Young|last5=Koh|first5=Young Hwan|last6=Lee|first6=Hyun Ju|last7=Han|first7=Joon Koo|title=Pyogenic hepatic abscesses: distinctive features from hypovascular hepatic malignancies on contrast-enhanced ultrasound with SH U 508A; early experience|journal=Ultrasound in Medicine & Biology|volume=30|issue=6|year=2004|pages=725–733|issn=03015629|doi=10.1016/j.ultrasmedbio.2004.03.006}}</ref><ref name="pmid18359914">{{cite journal |vauthors=Liu GJ, Lu MD, Xie XY, Xu HX, Xu ZF, Zheng YL, Liang JY, Wang W |title=Real-time contrast-enhanced ultrasound imaging of infected focal liver lesions |journal=J Ultrasound Med |volume=27 |issue=4 |pages=657–66 |year=2008 |pmid=18359914 |doi= |url=}}</ref><ref name="WilsonKim2007">{{cite journal|last1=Wilson|first1=Stephanie R.|last2=Kim|first2=Tae Kyoung|last3=Jang|first3=Hyun-Jung|last4=Burns|first4=Peter N.|title=Enhancement Patterns of Focal Liver Masses: Discordance Between Contrast-Enhanced Sonography and Contrast-Enhanced CT and MRI|journal=American Journal of Roentgenology|volume=189|issue=1|year=2007|pages=W7–W12|issn=0361-803X|doi=10.2214/AJR.06.1060}}</ref><ref name="GuoXu2015">{{cite journal|last1=Guo|first1=Le-Hang|last2=Xu|first2=Hui-Xiong|title=Contrast-Enhanced Ultrasound in the Diagnosis of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma: Controversy over the ASSLD Guideline|journal=BioMed Research International|volume=2015|year=2015|pages=1–5|issn=2314-6133|doi=10.1155/2015/349172}}</ref><ref name="pmid9562062">{{cite journal |vauthors=Choi BI, Kim TK, Han JK |title=MRI of clonorchiasis and cholangiocarcinoma |journal=J Magn Reson Imaging |volume=8 |issue=2 |pages=359–66 |year=1998 |pmid=9562062 |doi= |url=}}</ref><ref name="KimChoi1997">{{cite journal|last1=Kim|first1=T K|last2=Choi|first2=B I|last3=Han|first3=J K|last4=Jang|first4=H J|last5=Cho|first5=S G|last6=Han|first6=M C|title=Peripheral cholangiocarcinoma of the liver: two-phase spiral CT findings.|journal=Radiology|volume=204|issue=2|year=1997|pages=539–543|issn=0033-8419|doi=10.1148/radiology.204.2.9240550}}</ref>
+* [[Hepatocellular carcinoma]]
+* [[Liver hemangioma]]
+* [[Liver abscess]]
+* [[Cirrhosis]]
+* [[Inflammatory]] [[lesions]]
+* [[Cholangiocarcinoma]]
+* [[Pancreatic carcinoma]]
+* [[Focal nodular hyperplasia]]<small>
+{| class="wikitable" style="border: 0px; font-size: 90%; margin: 5px;" align="center"
+! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Disease
+| colspan="13" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" |'''Clinical manifestations'''
+! colspan="2" rowspan="2" style="background:#4479BA; color: #FFFFFF;" align="center" |Diagnosis
+! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Comments
+|-
+| colspan="9" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" |'''Symptoms'''
+! colspan="4" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" | Signs
+|-
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Abdominal Pain
+! colspan="1" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" | Fever
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Rigors and chills
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Nausea or vomiting
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Jaundice
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Constipation
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Diarrhea
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Weight loss
+! style="background:#4479BA; color: #FFFFFF;" align="center" |GI bleeding
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Hypo-
+tension
+! colspan="1" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" | Guarding
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Rebound Tenderness
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Bowel sounds
+! colspan="1" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" | Lab Findings
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Imaging
+|-
+| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Hepatocellular carcinoma]]/[[Metastasis]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |RUQ
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* Normal
+* Hyperactive if obstruction present
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* High levels of [[Alpha-fetoprotein|AFP]] in serum
+* Abnormal [[Liver function test|liver function tests]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* US
+* CT
+* Liver biopsy
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+Other symptoms:
+* [[Splenomegaly]]
+* [[Variceal bleeding]]
+* [[Ascites]]
+* [[Spider nevi]]
+* [[Asterixis]]
+|-
+| colspan="1" rowspan="1" style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Cholangiocarcinoma]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Epigastric]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |−
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* Increased [[amylase]] / [[lipase]]
+* Increased stool fat content
+* Pancreatic function test
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |CT scan
+* Calcification
+* Pseudocyst
+* Dilation of main pancreatic duct
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* Predisposes to pancreatic cancer
+|-
+| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Pancreatic carcinoma]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Epigastric]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |−
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |N
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* ↑ [[Alkaline phosphatase]]
+* ↑ [[Bilirubin|serum bilirubin]]
+* ↑ [[gamma-glutamyl transpeptidase]]
+* ↑ [[CA 19-9]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* [[Computed tomography|MDCT]] with   [[Positron emission tomography|PET]]/[[Computed tomography|CT]]
+* MRI
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+[[Skin]] manifestations may include:
+* [[Bullous pemphigoid]]
+* [[Mucous membrane pemphigoid|Cicatricial pemphigoid]]
+* [[Thrombophlebitis|Migratory superficial thrombophlebitis]] (classic [[Trousseau's syndrome]])
+* [[Panniculitis|Pancreatic panniculitis]]
+|-
+| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Focal nodular hyperplasia]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |Diffuse
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |Normal or hyperactive
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* [[Anti-neutrophil cytoplasmic antibody]] ([[P-ANCA]]) in [[Ulcerative colitis]]
+* [[Anti saccharomyces cerevisiae antibodies]] (ASCA) in [[Crohn's disease]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* [[String sign]] on [[abdominal x-ray]] in [[Crohn's disease]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+Extra intestinal findings:
+* [[Uveitis]]
+* [[Arthritis]]
+|-
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Disease
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Abdominal Pain
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Fever
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Rigors and chills
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Nausea or vomiting
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Jaundice
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Constipation
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Diarrhea
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Weight loss
+! style="background:#4479BA; color: #FFFFFF;" align="center" |GI bleeding
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Hypo-
+tension
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Guarding
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Rebound Tenderness
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Bowel sounds
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Lab Findings
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Imaging
+! style="background:#4479BA; color: #FFFFFF;" align="center" |Comments
+|-
+| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Gallbladder cancer]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |Diffuse
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* [[Thrombocytopenia]]
+* [[Hypoalbuminemia]]
+* [[Small intestinal]] [[biopsy]] for [[Tropheryma whipplei]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[Whipple's disease other diagnostic studies|Endoscopy]] is used to confirm diagnosis.
+Images used to find complications
+*[[Whipple's disease x ray|Chest and joint x-ray]]
+*[[Whipple's disease CT|CT]]
+*[[Whipple's disease MRI|MRI]]
+*[[Whipple's disease ultrasound|Echocardiography]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |Extra intestinal findings:
+* [[Uveitis]]
+* [[Endocarditis]]
+* [[Encephalitis]]
+* [[Dementia]]
+* [[Hepatosplenomegaly]]
+* [[Arthritis]]
+* [[Ascites]]
+|-
+| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Liver hemangioma]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[RUQ]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive in Hep A and E
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive in fulminant hepatitis
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive in acute
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* Abnormal LFTs
+* Viral serology
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* US
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* Hep A and E have fecal-oral route of transmission
+* Hep B and C transmits via blood transfusion and sexual contact.
+|-
+| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Liver abscess]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |RUQ
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |Normal or hypoactive
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* CBC
+* Blood cultures
+* Abnormal [[Liver function test|liver function tests]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* US
+* CT
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+|-
+| style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Cirrhosis|Cirrhosis]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[RUQ]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* [[Hypoalbuminemia]]
+* Prolonged PT
+* Abnormal LFTs
+* [[Hyponatremia]]
+* [[Thrombocytopenia]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |US
+* Nodular, shrunken liver
+* [[Ascites]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* Stigmata of liver disease
+* Cruveilhier- Baumgarten murmur
+|- style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+|-
+| style="padding: 5px 5px; background: #DCDCDC;" align="center" |Inflammatory lesions
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[RUQ]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* [[Hypoalbuminemia]]
+* Prolonged PT
+* Abnormal LFTs
+* [[Hyponatremia]]
+* [[Thrombocytopenia]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |US
+* Nodular, shrunken liver
+* [[Ascites]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+* Stigmata of liver disease
+* Cruveilhier- Baumgarten murmur
+|-
-*[[Hepatitis]] and liver diseases
+|}'''Abbreviations:[[RUQ]]'''= Right upper quadrant of the abdomen, '''LUQ'''= Left upper quadrant, '''LLQ'''= Left lower quadrant, '''RLQ'''= Right lower quadrant, '''LFT'''= Liver function test, SIRS= [[Systemic inflammatory response syndrome]], '''[[ERCP]]'''= [[Endoscopic retrograde cholangiopancreatography]], '''IV'''= Intravenous, '''N'''= Normal, '''AMA'''= Anti mitochondrial antibodies, '''[[LDH]]'''= [[Lactate dehydrogenase]], '''GI'''= Gastrointestinal, '''CXR'''= Chest X ray, '''IgA'''= [[Immunoglobulin A]], '''IgG'''= [[Immunoglobulin G]], '''IgM'''= [[Immunoglobulin M]], '''CT'''= [[Computed tomography]], '''[[PMN]]'''= Polymorphonuclear cells, '''[[ESR]]'''= [[Erythrocyte sedimentation rate]], '''[[CRP]]'''= [[C-reactive protein]], TS= [[Transferrin saturation]], SF= Serum [[Ferritin]], SMA= [[Superior mesenteric artery]], SMV= [[Superior mesenteric vein]], ECG= [[Electrocardiogram]]<small>
-*[[Gallstones]], [[cholecystitis]]
-*[[Peptic ulcer]]
-*[[Pancreatic cancer]], [[pancreatitis]]
 ==References==
 {{reflist|2}}
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+[[Category:Gastroenterology]]
+[[Category:Surgery]]
+[[Category:Hepatology]]

Gallbladder cancer differential diagnosis: Difference between revisions

Latest revision as of 21:59, 8 February 2019

Overview

Differentiatiating Gallbladder cancer from other Diseases

References

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