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{{Langerhans cell histiocytosis}}
{{Langerhans cell histiocytosis}}
{{CMG}}
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==Overview==
Chest X-ray may be helpful in the diagnosis of Langerhans cell histiocytosis. Findings on Chest X-ray suggestive of Langerhans cell histiocytosis include mild hyperinflation, coarse reticular [[interstitial]] markings, and peripheral ring shadows suggesting [[cyst]]s formation.


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==X-Ray==
* Findings on [[skull]] X-ray suggestive of Langerhans cell histiocytosis include a well-defined, punched-out, lytic lesions with sclerotic borders.<ref name="pmid23907805">{{cite journal| author=Khung S, Budzik JF, Amzallag-Bellenger E, Lambilliote A, Soto Ares G, Cotten A et al.| title=Skeletal involvement in Langerhans cell histiocytosis. | journal=Insights Imaging | year= 2013 | volume= 4 | issue= 5 | pages= 569-79 | pmid=23907805 | doi=10.1007/s13244-013-0271-7 | pmc=PMC3781243 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23907805 }} </ref>
* Chest X-ray may be helpful in the diagnosis of Langerhans cell histiocytosis.<ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref>
* Findings on chest X-ray suggestive of Langerhans cell histiocytosis include:<ref name="urlPulmonary Langerhans Cell Histiocytosis | RadioGraphics">{{cite web |url=https://pubs.rsna.org/doi/full/10.1148/rg.271065044 |title=Pulmonary Langerhans Cell Histiocytosis &#124; RadioGraphics |format= |work= |accessdate=}}</ref><ref name="pmid24996395">{{cite journal |vauthors=Castoldi MC, Verrioli A, De Juli E, Vanzulli A |title=Pulmonary Langerhans cell histiocytosis: the many faces of presentation at initial CT scan |journal=Insights Imaging |volume=5 |issue=4 |pages=483–92 |date=August 2014 |pmid=24996395 |pmc=4141336 |doi=10.1007/s13244-014-0338-0 |url=}}</ref><ref name="pmid22429393">{{cite journal |vauthors=Suri HS, Yi ES, Nowakowski GS, Vassallo R |title=Pulmonary langerhans cell histiocytosis |journal=Orphanet J Rare Dis |volume=7 |issue= |pages=16 |date=March 2012 |pmid=22429393 |pmc=3342091 |doi=10.1186/1750-1172-7-16 |url=}}</ref>
:* Mild hyperinflation
:* Coarse reticular [[interstitial]] markings
:* Peripheral ring shadows suggesting [[cyst]]s formation
* Findings on [[bone]] X-ray suggestive of Langerhans cell histiocytosis include:
:* Well-defined lytic [[diaphysis|diaphyseal]] lesion
:* Dense consolidated [[periosteal reaction]]
:* No cortical breach or soft-tissue mass


==Overview==
==Gallery==
==Chest X Ray==
<gallery>
Radiology will show osteolytic bone lesions and damage to the lung. Latter may be evident in CXR with micronodular and [[interstitial]] infiltrate in the mid and lower zone of lung, with sparing of the [[Costophrenic angle]] or [[honeycomb]] appearance in older lesions. [[MRI]] and [[CT]] may show infiltration in [[sella turcica]].
Image:
Langerhans Skull X ray 2.jpg|Langerhans cell histiocytosis punched-out lytic skull lesions<ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref>
Image:
Langerhans Skull X ray 3.jpg|Langerhans cell histiocytosis punched-out lytic skull lesions<ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref>
Image:
Langerhans Skull X ray.jpg|Langerhans cell histiocytosis punched-out lytic skull lesions<ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref>
Image:
Langerhans CXR.jpeg|Chest X-ray of Langerhans cell histiocytosis<ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref>
Image:
Langerhans histocytosis X-ray.jpg|Eosinophilic granuloma of the femur<ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref>
Image:
Langerhans X ray.jpeg|Severe uniform joint space narrowing of the left femoroacetabular joint with moderate osteophytosis<ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref>
</gallery>


==References==
==References==
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Latest revision as of 02:26, 28 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Chest X-ray may be helpful in the diagnosis of Langerhans cell histiocytosis. Findings on Chest X-ray suggestive of Langerhans cell histiocytosis include mild hyperinflation, coarse reticular interstitial markings, and peripheral ring shadows suggesting cysts formation.

X-Ray

  • Findings on skull X-ray suggestive of Langerhans cell histiocytosis include a well-defined, punched-out, lytic lesions with sclerotic borders.[1]
  • Chest X-ray may be helpful in the diagnosis of Langerhans cell histiocytosis.[2]
  • Findings on chest X-ray suggestive of Langerhans cell histiocytosis include:[3][4][5]
  • Mild hyperinflation
  • Coarse reticular interstitial markings
  • Peripheral ring shadows suggesting cysts formation
  • Findings on bone X-ray suggestive of Langerhans cell histiocytosis include:

Gallery

  • Langerhans cell histiocytosis punched-out lytic skull lesions[2]

    Langerhans cell histiocytosis punched-out lytic skull lesions[2]

  • Langerhans cell histiocytosis punched-out lytic skull lesions[2]

    Langerhans cell histiocytosis punched-out lytic skull lesions[2]

  • Langerhans cell histiocytosis punched-out lytic skull lesions[2]

    Langerhans cell histiocytosis punched-out lytic skull lesions[2]

  • Chest X-ray of Langerhans cell histiocytosis[2]

    Chest X-ray of Langerhans cell histiocytosis[2]

  • Eosinophilic granuloma of the femur[2]

    Eosinophilic granuloma of the femur[2]

  • Severe uniform joint space narrowing of the left femoroacetabular joint with moderate osteophytosis[2]

    Severe uniform joint space narrowing of the left femoroacetabular joint with moderate osteophytosis[2]

References

  1. ↑ Khung S, Budzik JF, Amzallag-Bellenger E, Lambilliote A, Soto Ares G, Cotten A; et al. (2013). "Skeletal involvement in Langerhans cell histiocytosis". Insights Imaging. 4 (5): 569–79. doi:10.1007/s13244-013-0271-7. PMC 3781243. PMID 23907805.
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016
  3. ↑ "Pulmonary Langerhans Cell Histiocytosis | RadioGraphics".
  4. ↑ Castoldi MC, Verrioli A, De Juli E, Vanzulli A (August 2014). "Pulmonary Langerhans cell histiocytosis: the many faces of presentation at initial CT scan". Insights Imaging. 5 (4): 483–92. doi:10.1007/s13244-014-0338-0. PMC 4141336. PMID 24996395.
  5. ↑ Suri HS, Yi ES, Nowakowski GS, Vassallo R (March 2012). "Pulmonary langerhans cell histiocytosis". Orphanet J Rare Dis. 7: 16. doi:10.1186/1750-1172-7-16. PMC 3342091. PMID 22429393.


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