Optic nerve glioma history and symptoms: Difference between revisions
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{{Optic nerve glioma}} | {{Optic nerve glioma}} | ||
{{CMG}} | {{CMG}}{{AE}}{{Simrat}} | ||
==Overview== | ==Overview== | ||
Symptoms of optic nerve glioma include [[proptosis]], unilateral or bilateral [[visual impairment]], involuntary eyeball movement, squinting, [[vomiting]], irritability, poor feeding , [[seizures]], deficits in muscle tone and strength, daytime [[sleepiness]], decreased [[memory]] and [[brain]] function, [[weight loss]], delayed growth and [[loss of appetite]]. | |||
==History== | |||
==Common Symptoms== | |||
Decreased vision (63%) is usually evident and can be documented with visual field examination if the child is old enough. Eventually mass effects will also occur, with [[proptosis]] and even intracranial sequelae including symptoms of raised [[intracranial pressure]], focal neurological deficits and [[hydrocephalus]] from distortion of the midbrain. Involvement of the [[hypothalamus]] may result in [[polyuria]] or [[polydipsia]].<ref name="radio"> Optic nerve glioma. Radiopedia(2015) http://radiopaedia.org/articles/optic-nerve-glioma Accessed on October 5 2015</ref> | |||
Common symptoms of optic pathway gliomas include: | |||
*[[Proptosis]] | |||
*Unilateral or bilateral [[visual impairment]]. | |||
*Optic nerve gliomas may present with symptoms of the [[obstructive hydrocephalus]], which includes: | |||
**[[Vomiting]] | |||
**[[Sleepiness]] | |||
**[[Poor feeding]] | |||
**[[Irritability]] | |||
**[[Seizures]] | |||
**Deficits in muscle tone and strength | |||
Other less common symptoms are: | |||
*Involuntary eye ball movement | |||
*Squinting | |||
*[[Hypothalamic]] gliomas may present with symptoms of the [[diencephalic syndrome]], which includes: | |||
**Daytime [[sleepiness]] | |||
**Decreased [[memory]] and [[brain]] function | |||
**[[Delayed growth]] | |||
**Loss of appetite and [[loss of weight]] | |||
*[[Precocious puberty]]- Due to involvement of hypothalamic-pituitary-gonadal axis precocious puberty may occur in 39 % of children with chiasmal optic nerve gliomas and NF-1.<ref name="pmid7869193">{{cite journal| author=Habiby R, Silverman B, Listernick R, Charrow J| title=Precocious puberty in children with neurofibromatosis type 1. | journal=J Pediatr | year= 1995 | volume= 126 | issue= 3 | pages= 364-7 | pmid=7869193 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7869193 }} </ref> In 10 to 20 percent of patients with optic pathway gliomas endocrinopathies due to hypothalamic extension are present. | |||
==References== | ==References== | ||
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[[Category:Neurology]] | [[Category:Neurology]] | ||
[[Category:Ophthalmology]] | [[Category:Ophthalmology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Ophthalmology]] | |||
[[Category:Neurosurgery]] | |||
Latest revision as of 14:47, 27 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Symptoms of optic nerve glioma include proptosis, unilateral or bilateral visual impairment, involuntary eyeball movement, squinting, vomiting, irritability, poor feeding , seizures, deficits in muscle tone and strength, daytime sleepiness, decreased memory and brain function, weight loss, delayed growth and loss of appetite.
History
Common Symptoms
Decreased vision (63%) is usually evident and can be documented with visual field examination if the child is old enough. Eventually mass effects will also occur, with proptosis and even intracranial sequelae including symptoms of raised intracranial pressure, focal neurological deficits and hydrocephalus from distortion of the midbrain. Involvement of the hypothalamus may result in polyuria or polydipsia.[1]
Common symptoms of optic pathway gliomas include:
- Proptosis
- Unilateral or bilateral visual impairment.
- Optic nerve gliomas may present with symptoms of the obstructive hydrocephalus, which includes:
- Vomiting
- Sleepiness
- Poor feeding
- Irritability
- Seizures
- Deficits in muscle tone and strength
Other less common symptoms are:
- Involuntary eye ball movement
- Squinting
- Hypothalamic gliomas may present with symptoms of the diencephalic syndrome, which includes:
- Daytime sleepiness
- Decreased memory and brain function
- Delayed growth
- Loss of appetite and loss of weight
- Precocious puberty- Due to involvement of hypothalamic-pituitary-gonadal axis precocious puberty may occur in 39 % of children with chiasmal optic nerve gliomas and NF-1.[2] In 10 to 20 percent of patients with optic pathway gliomas endocrinopathies due to hypothalamic extension are present.
References
- ↑ Optic nerve glioma. Radiopedia(2015) http://radiopaedia.org/articles/optic-nerve-glioma Accessed on October 5 2015
- ↑ Habiby R, Silverman B, Listernick R, Charrow J (1995). "Precocious puberty in children with neurofibromatosis type 1". J Pediatr. 126 (3): 364–7. PMID 7869193.