Chondrosarcoma differential diagnosis: Difference between revisions

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{{Chondrosarcoma}}
[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Chondrosarcoma]]
{{CMG}}
{{CMG}};{{AE}} {{Rohan}}
==Overview==
==Overview==
Chondrosarcoma must be differentiated from other diseases such as [[chondroma]], [[enchondroma]], [[osteochondroma]], and [[osteosarcoma]].
==Differentiating chondrosarcoma from other Diseases==
==Differentiating chondrosarcoma from other Diseases==
Differential diagnosis of chondrosarcoma includes:<ref name="librepathology">librepathology.Chondrosarcoma.http://librepathology.org/wiki/index.php/Chondrosarcoma</ref>
*Chondrosarcoma must be differentiated from following bone disorders:<ref>{{cite book | last = Peabody | first = Terrance | title = Orthopaedic oncology : primary and metastatic tumors of the skeletal system | publisher = Springer | location = Cham | year = 2014 | isbn = 9783319073224 }}</ref><ref>{{cite book | last = Czerniak | first = Bogdan | title = Dorfman and Czerniak's bone tumors | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2016 | isbn = 9780323023962 }}</ref><ref name="pmid3021775">{{cite journal| author=Frassica FJ, Unni KK, Beabout JW, Sim FH| title=Dedifferentiated chondrosarcoma. A report of the clinicopathological features and treatment of seventy-eight cases. | journal=J Bone Joint Surg Am | year= 1986 | volume= 68 | issue= 8 | pages= 1197-205 | pmid=3021775 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3021775  }} </ref><ref name="pmid9827715">{{cite journal| author=Björnsson J, McLeod RA, Unni KK, Ilstrup DM, Pritchard DJ| title=Primary chondrosarcoma of long bones and limb girdles. | journal=Cancer | year= 1998 | volume= 83 | issue= 10 | pages= 2105-19 | pmid=9827715 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9827715  }} </ref>
*[[Chondroma]]
 
*[[Enchondroma]]
{|
*[[Synovial chondromatosis]]
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Disease
*[[Osteosarcoma]]
! align="center" style="background:#4479BA; color: #FFFFFF;" + |'''Malignant lesion in patients'''
'''> 40 years'''
! align="center" style="background:#4479BA; color: #FFFFFF;" + |'''chondrogenic Histology'''
! align="center" style="background:#4479BA; color: #FFFFFF;" + | '''Sacral lesions''' in elderly
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Treatment is wide resection alone
|-
! align="center" style="background:#DCDCDC;" + |Chondrosarcoma
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
|-
! align="center" style="background:#DCDCDC;" + |[[Metastasis|Metastic disease]]
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | -
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | -
|-
! align="center" style="background:#DCDCDC;" + |[[Lymphoma]]
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | -
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | -
|-
! align="center" style="background:#DCDCDC;" + |[[Myeloma]]
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | -
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | -
|-
! align="center" style="background:#DCDCDC;" + |Malignant Fibrous Histiocytoma
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | -
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | -
|-
! align="center" style="background:#DCDCDC;" + |Secondary sarcoma
! align="center" style="background:#F5F5F5;" + | +
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
|-
! align="center" style="background:#DCDCDC;" + |[[Enchondroma]]  
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | +
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
|-
! align="center" style="background:#DCDCDC;" + |Periosteal [[chondroma]]
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | +
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
|-
! align="center" style="background:#DCDCDC;" + |[[Osteochondroma]]
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | +
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
|-
! align="center" style="background:#DCDCDC;" + |Parosteal [[osteosarcoma]]
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | +
|-
! align="center" style="background:#DCDCDC;" + |[[Adamantinoma]]
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | +
|-
! align="center" style="background:#DCDCDC;" + |[[Chordoma]]
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | +
|-
! align="center" style="background:#DCDCDC;" + |[[Squamous cell carcinoma]]
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | -
! align="center" style="background:#F5F5F5;" + | +
|-
|}


==References==
==References==
{{reflist|2}}
{{reflist|2}}
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Latest revision as of 22:29, 20 February 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

Overview

Chondrosarcoma must be differentiated from other diseases such as chondroma, enchondroma, osteochondroma, and osteosarcoma.

Differentiating chondrosarcoma from other Diseases

  • Chondrosarcoma must be differentiated from following bone disorders:[1][2][3][4]
Disease Malignant lesion in patients

> 40 years

chondrogenic Histology Sacral lesions in elderly Treatment is wide resection alone
Chondrosarcoma + + + +
Metastic disease + - + -
Lymphoma + - + -
Myeloma + - + -
Malignant Fibrous Histiocytoma + - + -
Secondary sarcoma + - - -
Enchondroma - + - -
Periosteal chondroma - + - -
Osteochondroma - + - -
Parosteal osteosarcoma - - - +
Adamantinoma - - - +
Chordoma - - - +
Squamous cell carcinoma - - - +

References

  1. ↑ Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
  2. ↑ Czerniak, Bogdan (2016). Dorfman and Czerniak's bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.
  3. ↑ Frassica FJ, Unni KK, Beabout JW, Sim FH (1986). "Dedifferentiated chondrosarcoma. A report of the clinicopathological features and treatment of seventy-eight cases". J Bone Joint Surg Am. 68 (8): 1197–205. PMID 3021775.
  4. ↑ Björnsson J, McLeod RA, Unni KK, Ilstrup DM, Pritchard DJ (1998). "Primary chondrosarcoma of long bones and limb girdles". Cancer. 83 (10): 2105–19. PMID 9827715.



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