Primary central nervous system lymphoma risk factors: Difference between revisions
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{{Primary central nervous system lymphoma}} | {{Primary central nervous system lymphoma}} | ||
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==Overview== | |||
The most potent risk factor in the development of primary central nervous system lymphoma is a weakened or suppressed immune system in individuals who have [[Acquired immunodeficiency syndrome|acquired immunodeficiency syndrome (AIDS)]], received an organ transplant and are on [[immunosuppressants]], inherited immunosuppressive disorders ([[IgA deficiency]], [[Wiskott-Aldrich syndrome]], [[ataxia telangiectasia]]), and [[autoimmune disorders]] ([[systemic lupus erythematosus]], [[rheumatoid arthritis]], [[myasthenia gravis]]). | |||
==Risk Factors== | |||
The most potent risk factor in the development of primary central nervous system lymphoma is a '''weakened or suppressed immune system''' in individuals who have:<ref name="riskpcnsl1">Risks of primary central nervous lymphoma. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/primary-cns-lymphoma/?region=on. Accessed on February 17, 2016</ref><ref name="ManentiDi Giuliano2013">{{cite journal|last1=Manenti|first1=G.|last2=Di Giuliano|first2=F.|last3=Bindi|first3=A.|last4=Liberto|first4=V.|last5=Funel|first5=V.|last6=Garaci|first6=F. G.|last7=Floris|first7=R.|last8=Simonetti|first8=G.|title=A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment|journal=Case Reports in Radiology|volume=2013|year=2013|pages=1–5|issn=2090-6862|doi=10.1155/2013/916348}}</ref><ref name="epidemiologyprimarycnslymphoma1">Epidemiology of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref><ref name="pmid18976024">{{cite journal| author=Bhagavathi S, Wilson JD| title=Primary central nervous system lymphoma. | journal=Arch Pathol Lab Med | year= 2008 | volume= 132 | issue= 11 | pages= 1830-4 | pmid=18976024 | doi=10.1043/1543-2165-132.11.1830 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18976024 }} </ref> | |||
*[[Acquired immunodeficiency syndrome|Acquired immunodeficiency syndrome (AIDS)]] | |||
:*The highest number of cases occur in individuals with AIDS. | |||
*Received an organ transplant and are on [[immunosuppressants]] | |||
*Inherited immunosuppressive disorder | |||
:*[[IgA deficiency]] | |||
:*[[Wiskott-Aldrich syndrome]] | |||
:*[[Ataxia telangiectasia]] | |||
:*[[Severe combined immunodeficiency|Severe combined immunodeficiency (SCID)]] | |||
:*[[Common variable immunodeficiency|Common variable immunodeficiency (CVID)]] | |||
*Autoimmune disorders | |||
:*[[Systemic lupus erythematosus]] | |||
:*[[Rheumatoid arthritis]] | |||
:*[[Sjögren's syndrome]] | |||
:*[[Myasthenia gravis]] | |||
:*[[Sarcoidosis]] | |||
:*[[Vasculitis]] | |||
==References== | ==References== | ||
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Latest revision as of 16:37, 20 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]
Overview
The most potent risk factor in the development of primary central nervous system lymphoma is a weakened or suppressed immune system in individuals who have acquired immunodeficiency syndrome (AIDS), received an organ transplant and are on immunosuppressants, inherited immunosuppressive disorders (IgA deficiency, Wiskott-Aldrich syndrome, ataxia telangiectasia), and autoimmune disorders (systemic lupus erythematosus, rheumatoid arthritis, myasthenia gravis).
Risk Factors
The most potent risk factor in the development of primary central nervous system lymphoma is a weakened or suppressed immune system in individuals who have:[1][2][3][4]
- The highest number of cases occur in individuals with AIDS.
- Received an organ transplant and are on immunosuppressants
- Inherited immunosuppressive disorder
- Autoimmune disorders
References
- ↑ Risks of primary central nervous lymphoma. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/primary-cns-lymphoma/?region=on. Accessed on February 17, 2016
- ↑ Manenti, G.; Di Giuliano, F.; Bindi, A.; Liberto, V.; Funel, V.; Garaci, F. G.; Floris, R.; Simonetti, G. (2013). "A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment". Case Reports in Radiology. 2013: 1–5. doi:10.1155/2013/916348. ISSN 2090-6862.
- ↑ Epidemiology of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016
- ↑ Bhagavathi S, Wilson JD (2008). "Primary central nervous system lymphoma". Arch Pathol Lab Med. 132 (11): 1830–4. doi:10.1043/1543-2165-132.11.1830. PMID 18976024.