Dermatofibroma classification: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
m (Bot: Removing from Primary care)
 
(20 intermediate revisions by 4 users not shown)
Line 1: Line 1:
__NOTOC__
{{Dermatofibroma}}
{{Dermatofibroma}}
{{CMG}};{{AE}}{{Homa}}
==Overview==
==Overview==
Dermatofibroma may be classified according to [[histopathology]] into three groups, variants that are prominent in architectural (low-power) properties, variants that are prominent in [[Cytological|cytologic]] or [[stromal]] (high-power) properties, and variants that have architectural (low) and [[cytological]] or [[stromal]] (high-power) properties.<br />


Dermatofibromas are classed as benign skin lesions, meaning that they are completely harmless, though they may be confused with a variety of subcutaneous tumours. Deep penetrating dermatofibromas may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like [[dermatofibrosarcoma protuberans]].
==Classification==
 
Dermatofibroma may be classified according to [[histopathology]] into three groups:<ref>{{Cite journal
| author = [[B. G. Zelger]], [[A. Sidoroff]] & [[B. Zelger]]
| title = Combined dermatofibroma: co-existence of two or more variant patterns in a single lesion
| journal = [[Histopathology]]
| volume = 36
| issue = 6
| pages = 529–539
| year = 2000
| pmid = 10849095
}}</ref><ref name="JonesCerio2006">{{cite journal|last1=Jones|first1=E. Wilson|last2=Cerio|first2=R.|last3=Smith|first3=N.P.|title=Epithelioid cell histiocytoma: a new entity|journal=British Journal of Dermatology|volume=120|issue=2|year=2006|pages=185–195|issn=00070963|doi=10.1111/j.1365-2133.1989.tb07782.x}}</ref><ref name="ZelgerZelger1996">{{cite journal|last1=Zelger|first1=B W|last2=Zelger|first2=B G|last3=Steiner|first3=H|last4=Ofner|first4=D|title=Aneurysmal and haemangiopericytoma-like fibrous histiocytoma.|journal=Journal of Clinical Pathology|volume=49|issue=4|year=1996|pages=313–318|issn=0021-9746|doi=10.1136/jcp.49.4.313}}</ref><ref>{{Cite journal
| author = [[J. S. Silverman]] & [[S. Brustein]]
| title = Myxoid dermatofibrohistiocytoma: an indolent post-traumatic tumor composed of CD34+ epithelioid and dendritic cells and factor XIIIa+ dendrophages
| journal = [[Journal of cutaneous pathology]]
| volume = 23
| issue = 6
| pages = 551–557
| year = 1996
| pmid = 9001986
}}</ref><ref>{{Cite journal
| author = [[B. G. Zelger]], [[E. Calonje]] & [[B. Zelger]]
| title = Myxoid dermatofibroma
| journal = [[Histopathology]]
| volume = 34
| issue = 4
| pages = 357–364
| year = 1999
| pmid = 10231403
}}</ref><ref>{{Cite journal
| author = [[E. J. Glusac]] & [[J. M. McNiff]]
| title = Epithelioid cell histiocytoma: a simulant of vascular and melanocytic neoplasms
| journal = [[The American Journal of dermatopathology]]
| volume = 21
| issue = 1
| pages = 1–7
| year = 1999
| pmid = 10027517
}}</ref><ref>{{Cite journal
| author = [[E. Calonje]], [[T. Mentzel]] & [[C. D. Fletcher]]
| title = Cellular benign fibrous histiocytoma. Clinicopathologic analysis of 74 cases of a distinctive variant of cutaneous fibrous histiocytoma with frequent recurrence
| journal = [[The American journal of surgical pathology]]
| volume = 18
| issue = 7
| pages = 668–676
| year = 1994
| pmid = 8017561
}}</ref><ref>{{Cite journal
| author = [[B. W. Zelger]], [[H. Steiner]] & [[H. Kutzner]]
| title = Clear cell dermatofibroma. Case report of an unusual fibrohistiocytic lesion
| journal = [[The American journal of surgical pathology]]
| volume = 20
| issue = 4
| pages = 483–491
| year = 1996
| pmid = 8604817
}}</ref><ref>{{Cite journal
| author = [[J. F. Val-Bernal]] & [[C. Mira]]
| title = Dermatofibroma with granular cells
| journal = [[Journal of cutaneous pathology]]
| volume = 23
| issue = 6
| pages = 562–565
| year = 1996
| pmid = 9001988
}}</ref>
 
*Variants that are prominent in architectural (low-power) properties
*Variants that are prominent in [[Cytological|cytologic]] or [[stromal]] (high-power) properties
*Variants that have architectural (low) and [[cytological]] or [[stromal]] (high-power) properties


==Classification==
<br />
 
{{familytree/start}}
{{familytree | | | | | | | | | A01 | | | | | | | | |A01=[[Histopathology]] varient of dermatofibroma}}
{{familytree | | |,|-|-|-|-|-|-|+|-|-|-|-|-|-|.| }}
{{familytree | | B01 | | | | | B02 | | | | | B03 |B01=Variants that are prominent in architectural (low-power) properties|B02=Variants that are prominent in [[Cytological|cytologic]] or [[stromal]] (high-power) properties|B03=Variants that have architectural (low) and [[cytological]] or [[stromal]] (high-power) properties}}
{{familytree | | |!| | | | | | |!| | | | | | |!| | }}
{{familytree | | C01 | | | | | C02 | | | | | C03 |C01=1. Deep penetrating dermatofibroma
2. [[Atrophic]] dermatofibroma
 
3. [[Aneurysmal Disease|Aneurysmal]] [[fibrous]] [[histiocytoma]]
 
4. [[Haemangiopericytoma]]-like [[fibrous]] histiocytoma
 
5. Palisading [[cutaneous]] [[fibrous]] histiocytoma
 
6. Lichenoid, erosive, & [[Ulcerated lesion|ulcerated]] dermatofibroma
 
7. [[Plaque]]-like dermal [[fibromatosis]], dermatofibroma|C02=1. [[Clear cell]] dermatofibroma
 
2. [[Granular cell]] dermatofibroma
 
3. [[Myofibroblast|Myofibroblastic]] dermatofibroma
 
4. [[Sclerotic fibroma|Sclerotic]] dermatofibroma
 
5. [[Keloid|Keloidal]] dermatofibroma 
 
6. Atypical/pseudosarcomatous [[fibrous]] [[histiocytoma]], dermatofibroma with monster [[Cells (biology)|cells]]
 
7. Hemosiderrhotic dermatofibroma
 
8. Cholesterotic/lipidized dermatofibroma 
 
9. Myxoid dermatofibroma 
 
10. Ossifying dermatofibroma
 
11. [[Pseudolymphoma|Pseudolymphomatous]] dermatofibroma
 
12. Dermatofibroma  with [[diffuse]] [[eosinophilic]] [[Infiltration (medical)|infiltrate]]|C03=1. [[Epithelioid cell]] [[histiocytoma]]
 
2. [[Cellular]] [[benign]] [[fibrous histiocytoma]]
 
3. [[Smooth muscle]] [[proliferation]] in dermatofibroma
 
4. [[Multinucleate]] [[cell]] angiohistiocytoma
 
5. [[Cellular]] neurothekeoma


Dermatofibromas are classed as benign skin lesions, meaning that they are completely harmless, though they may be confused with a variety of subcutaneous tumours. Deep penetrating dermatofibromas may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like [[dermatofibrosarcoma protuberans]].
6. Combined dermatofibroma}}
{|


==References==
==References==
Line 12: Line 133:
{{Reflist|2}}
{{Reflist|2}}


[[Category:Needs content]]
[[Category:Medicine]]
[[Category:Oncology]]
[[Category:Up-To-Date]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Disease]]

Latest revision as of 21:17, 29 July 2020

Dermatofibroma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Dermatofibroma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Interventions

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Dermatofibroma classification On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Dermatofibroma classification

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Dermatofibroma classification

CDC on Dermatofibroma classification

Dermatofibroma classification in the news

Blogs on Dermatofibroma classification

Directions to Hospitals Treating Type page name here

Risk calculators and risk factors for Dermatofibroma classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]

Overview

Dermatofibroma may be classified according to histopathology into three groups, variants that are prominent in architectural (low-power) properties, variants that are prominent in cytologic or stromal (high-power) properties, and variants that have architectural (low) and cytological or stromal (high-power) properties.

Classification

Dermatofibroma may be classified according to histopathology into three groups:[1][2][3][4][5][6][7][8][9]

  • Variants that are prominent in architectural (low-power) properties
  • Variants that are prominent in cytologic or stromal (high-power) properties
  • Variants that have architectural (low) and cytological or stromal (high-power) properties


 
 
 
 
 
 
 
 
Histopathology varient of dermatofibroma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Variants that are prominent in architectural (low-power) properties
 
 
 
 
Variants that are prominent in cytologic or stromal (high-power) properties
 
 
 
 
Variants that have architectural (low) and cytological or stromal (high-power) properties
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1. Deep penetrating dermatofibroma

2. Atrophic dermatofibroma

3. Aneurysmal fibrous histiocytoma

4. Haemangiopericytoma-like fibrous histiocytoma

5. Palisading cutaneous fibrous histiocytoma

6. Lichenoid, erosive, & ulcerated dermatofibroma

7. Plaque-like dermal fibromatosis, dermatofibroma
 
 
 
 
1. Clear cell dermatofibroma

2. Granular cell dermatofibroma

3. Myofibroblastic dermatofibroma

4. Sclerotic dermatofibroma

5. Keloidal dermatofibroma

6. Atypical/pseudosarcomatous fibrous histiocytoma, dermatofibroma with monster cells

7. Hemosiderrhotic dermatofibroma

8. Cholesterotic/lipidized dermatofibroma

9. Myxoid dermatofibroma

10. Ossifying dermatofibroma

11. Pseudolymphomatous dermatofibroma

12. Dermatofibroma with diffuse eosinophilic infiltrate
 
 
 
 
1. Epithelioid cell histiocytoma

2. Cellular benign fibrous histiocytoma

3. Smooth muscle proliferation in dermatofibroma

4. Multinucleate cell angiohistiocytoma

5. Cellular neurothekeoma

6. Combined dermatofibroma

References

  1. ↑ B. G. Zelger, A. Sidoroff & B. Zelger (2000). "Combined dermatofibroma: co-existence of two or more variant patterns in a single lesion". Histopathology. 36 (6): 529–539. PMID 10849095.
  2. ↑ Jones, E. Wilson; Cerio, R.; Smith, N.P. (2006). "Epithelioid cell histiocytoma: a new entity". British Journal of Dermatology. 120 (2): 185–195. doi:10.1111/j.1365-2133.1989.tb07782.x. ISSN 0007-0963.
  3. ↑ Zelger, B W; Zelger, B G; Steiner, H; Ofner, D (1996). "Aneurysmal and haemangiopericytoma-like fibrous histiocytoma". Journal of Clinical Pathology. 49 (4): 313–318. doi:10.1136/jcp.49.4.313. ISSN 0021-9746.
  4. ↑ J. S. Silverman & S. Brustein (1996). "Myxoid dermatofibrohistiocytoma: an indolent post-traumatic tumor composed of CD34+ epithelioid and dendritic cells and factor XIIIa+ dendrophages". Journal of cutaneous pathology. 23 (6): 551–557. PMID 9001986.
  5. ↑ B. G. Zelger, E. Calonje & B. Zelger (1999). "Myxoid dermatofibroma". Histopathology. 34 (4): 357–364. PMID 10231403.
  6. ↑ E. J. Glusac & J. M. McNiff (1999). "Epithelioid cell histiocytoma: a simulant of vascular and melanocytic neoplasms". The American Journal of dermatopathology. 21 (1): 1–7. PMID 10027517.
  7. ↑ E. Calonje, T. Mentzel & C. D. Fletcher (1994). "Cellular benign fibrous histiocytoma. Clinicopathologic analysis of 74 cases of a distinctive variant of cutaneous fibrous histiocytoma with frequent recurrence". The American journal of surgical pathology. 18 (7): 668–676. PMID 8017561.
  8. ↑ B. W. Zelger, H. Steiner & H. Kutzner (1996). "Clear cell dermatofibroma. Case report of an unusual fibrohistiocytic lesion". The American journal of surgical pathology. 20 (4): 483–491. PMID 8604817.
  9. ↑ J. F. Val-Bernal & C. Mira (1996). "Dermatofibroma with granular cells". Journal of cutaneous pathology. 23 (6): 562–565. PMID 9001988.
Retrieved from "https://www.wikidoc.org/index.php?title=Dermatofibroma_classification&oldid=1636977"