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{{Thymoma}}
{{Thymoma}}
{{CMG}}; {{AE}} {{AM}}
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==Overview==
==Overview==
Thymoma is clinically diagnosed by radiological studies and lab work is ususally used to diagnose associated disorders.
[[Medical laboratory|Laboratory]] findings associated with thymoma may include [[antibodies]] against the [[acetylcholine receptor]], abnormal [[electrolyte]]s, [[renal]], and [[liver function tests]].


==Laboratory Findings==
==Laboratory Findings==
If the suspicion is high, some [[blood test]]s are often performed to look for associated problems or possible spread. These include: [[full blood count]], [[protein electrophoresis]], [[antibodies]] to the [[acetylcholine receptor]] (indicative of [[myasthenia gravis]]), [[electrolyte]]s, [[liver enzyme]]s and [[renal function]].<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref>
[[Patient|Patients]] with thymoma can have the following [[Medical laboratory|laboratory]] findings:<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref>
*[[Pure red cell aplasia]] on [[bone marrow biopsy]]
*Hypogammaglobulinemia on [[protein electrophoresis]]<ref>{{Cite journal
| author = [[Y. Jamilloux]], [[H. Frih]], [[C. Bernard]], [[C. Broussolle]], [[P. Petiot]], [[N. Girard]] & [[P. Seve]]
| title = &#91;Thymoma and autoimmune diseases&#93;
| journal = [[La Revue de medecine interne]]
| volume = 39
| issue = 1
| pages = 17–26
| year = 2018
| month = January
| doi = 10.1016/j.revmed.2017.03.003
| pmid = 28365191
}}</ref>
*[[Antibodies]] to the [[acetylcholine receptor]] (indicative of [[myasthenia gravis]])
*[[Liver enzyme]]s derangement
*[[Hypoalbuminemia]]<ref>{{Cite journal
| author = [[Shin Hye Yoo]], [[Hyean-Ji Kim]], [[Jeong-Han Kim]], [[Gyeong-Won Lee]], [[Jeong Hee Lee]], [[Se Hyun Kim]], [[Ji-Won Kim]], [[Jin Won Kim]], [[Jeong-Ok Lee]], [[Yu Jung Kim]], [[Keun-Wook Lee]], [[Jee Hyun Kim]], [[Soo-Mee Bang]] & [[Jong Seok Lee]]
| title = Nephrotic syndrome associated with metastatic thymoma treated with chemotherapy
| journal = [[Medicine]]
| volume = 96
| issue = 1
| pages = e5408
| year = 2017
| month = January
| doi = 10.1097/MD.0000000000005408
| pmid = 28072685
}}</ref>
*[[Proteinuria]]<ref>{{Cite journal
| author = [[Shin Hye Yoo]], [[Hyean-Ji Kim]], [[Jeong-Han Kim]], [[Gyeong-Won Lee]], [[Jeong Hee Lee]], [[Se Hyun Kim]], [[Ji-Won Kim]], [[Jin Won Kim]], [[Jeong-Ok Lee]], [[Yu Jung Kim]], [[Keun-Wook Lee]], [[Jee Hyun Kim]], [[Soo-Mee Bang]] & [[Jong Seok Lee]]
| title = Nephrotic syndrome associated with metastatic thymoma treated with chemotherapy
| journal = [[Medicine]]
| volume = 96
| issue = 1
| pages = e5408
| year = 2017
| month = January
| doi = 10.1097/MD.0000000000005408
| pmid = 28072685
}}</ref>
*[[Hyponatremia]]
*[[Hypercholesterolemia]]
*[[ANA|Antineutrophil antibody]]
*[[Anti-nuclear antibody]] (indicative of [[autoimmune hepatitis]])<ref>{{Cite journal
| author = [[Tomoki Nishimura]], [[Hiroaki Tsunezuka]], [[Naoko Miyata]] & [[Masayoshi Inoue]]
| title = Autoimmune hepatitis during preoperative chemotherapy in a patient with thymoma
| journal = [[Interactive cardiovascular and thoracic surgery]]
| year = 2019
| month = June
| doi = 10.1093/icvts/ivz138
| pmid = 31177282
}}</ref>


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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Latest revision as of 14:23, 15 August 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [2] Ahmad Al Maradni, M.D. [3]

Overview

Laboratory findings associated with thymoma may include antibodies against the acetylcholine receptor, abnormal electrolytes, renal, and liver function tests.

Laboratory Findings

Patients with thymoma can have the following laboratory findings:[1]

References

  1. ↑ Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17 (7): 2280–9. PMID 10561285. Retrieved 2012-01-18. Unknown parameter |month= ignored (help)
  2. ↑ Y. Jamilloux, H. Frih, C. Bernard, C. Broussolle, P. Petiot, N. Girard & P. Seve (2018). "[Thymoma and autoimmune diseases]". La Revue de medecine interne. 39 (1): 17–26. doi:10.1016/j.revmed.2017.03.003. PMID 28365191. Unknown parameter |month= ignored (help)
  3. ↑ Shin Hye Yoo, Hyean-Ji Kim, Jeong-Han Kim, Gyeong-Won Lee, Jeong Hee Lee, Se Hyun Kim, Ji-Won Kim, Jin Won Kim, Jeong-Ok Lee, Yu Jung Kim, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang & Jong Seok Lee (2017). "Nephrotic syndrome associated with metastatic thymoma treated with chemotherapy". Medicine. 96 (1): e5408. doi:10.1097/MD.0000000000005408. PMID 28072685. Unknown parameter |month= ignored (help)
  4. ↑ Shin Hye Yoo, Hyean-Ji Kim, Jeong-Han Kim, Gyeong-Won Lee, Jeong Hee Lee, Se Hyun Kim, Ji-Won Kim, Jin Won Kim, Jeong-Ok Lee, Yu Jung Kim, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang & Jong Seok Lee (2017). "Nephrotic syndrome associated with metastatic thymoma treated with chemotherapy". Medicine. 96 (1): e5408. doi:10.1097/MD.0000000000005408. PMID 28072685. Unknown parameter |month= ignored (help)
  5. ↑ Tomoki Nishimura, Hiroaki Tsunezuka, Naoko Miyata & Masayoshi Inoue (2019). "Autoimmune hepatitis during preoperative chemotherapy in a patient with thymoma". Interactive cardiovascular and thoracic surgery. doi:10.1093/icvts/ivz138. PMID 31177282. Unknown parameter |month= ignored (help)

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