Wilms' tumor CT: Difference between revisions

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{{Wilms' tumor}}
{{Wilms' tumor}}


==Overview==
==Overview==
CT scan may be helpful in the diagnosis of wilms' tumor.
Abdominal [[CT scan]] may be helpful in the diagnosis of Wilms tumor.Findings on [[CT scan]] which can be suggestive of  Wilms tumor include soft-tissue density masses,  areas of [[calcification]] (~10%) and fat-density regions. [[CT]] is better than [[ultrasonography]] in detecting small lesions of tumor. [[CT scan]] of the chest can be helpful to diagnose [[Metastasis|lung metastasis]].
 
==CT scan==
* Abdominal CT scan may be helpful in the diagnosis of Wilms tumor. Findings on CT scan suggestive of Wilms tumor include:<ref name="pmid4080660">{{cite journal |vauthors=Cahan LD |title=Failure of encephalo-duro-arterio-synangiosis procedure in moyamoya disease |journal=Pediatr Neurosci |volume=12 |issue=1 |pages=58–62 |date=1985 |pmid=4080660 |doi= |url=}}</ref><ref name="radio">Wilms tumour. Dr Tim Luijkx and Dr Frank Gaillard et al. Radiopaedia.org 2015.http://radiopaedia.org/articles/wilms-tumour </ref><ref name="pmid10813321">{{cite journal |vauthors=Gow KW, Roberts IF, Jamieson DH, Bray H, Magee JF, Murphy JJ |title=Local staging of Wilms' tumor--computerized tomography correlation with histological findings |journal=J. Pediatr. Surg. |volume=35 |issue=5 |pages=677–9 |date=May 2000 |pmid=10813321 |doi=10.1053/jpsu.2000.5941 |url=}}</ref>
** Heterogeneous soft-tissue density masses
**These masses have frequent areas of [[calcification]] (~10%) and fat-density regions
**[[Lymph node]] [[metastasis]]
**Invasion of surrounding organs
**[[Thrombus]] in or occlusion of the [[renal vein]] and/or the [[inferior vena cava]]
**Abdominal [[Lymph node|lymph nodes]] and contralateral involvement
**Estimate tumor size and volume and to plan surgical management
**Determine stage based on tumor size and structures involved


==CT==
*Chest CT scan can be helpful to diagnose [[lung]] [[metastasis]].


Wilms tumours are heterogeneous soft-tissue density masses with frequent areas of calcification (~10%) and fat-density regions. Enhancement is also patchy, and allows for better delineation of the relationship between the mass and kidney. 20% of cases have lung metastases at time of diagnosis.<ref name=radio> Wilms tumour. Dr Tim Luijkx and Dr Frank Gaillard et al. Radiopaedia.org 2015.http://radiopaedia.org/articles/wilms-tumour </ref>
[[File:Wilms-tumour CT.jpg|center|thumb|300x300px|CT abdomen showing Wilms tumor
Source:Radiopedia
Case courtesy of Dr Jeremy Jones,<ref><nowiki>https://radiopaedia.org/cases/8084</nowiki></ref>
]]


CT scan shows a renal mass which often shows one or more of the following: areas of hemorrhage, invasion of surrounding organs, thrombus in or occlusion of the renal vein and/or the inferior vena cava, abdominal lymph nodes and contralateral involvement.
<br clear="left" />
A preoperative CT scan helps to better estimate tumor size and volume and to plan surgical management more successfully. It is a useful tool to determine stage based on tumor size and structures involved.
[[File:Wilms-tumour- coronal view .jpg|center|thumb|300x300px|Wilms tumor - coronal view
<ref> Pshak TJ, Cho DS, Hayes KL, Vemulakonda VM. Correlation between CT-estimated tumor volume, pathologic tumor volume, and final pathologic specimen weight in children with Wilms' tumor.
source: radiopedia<ref>Case courtesy of Dr Jeremy Jones, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/8084">rID: 8084</a></ref>  


J Pediatr Urol. 2014 Feb;10(1):148-54. doi: 10.1016/j.jpurol.2013.08.001. Epub 2013 Sep 12. </ref><ref> McDonald K, Duffy P, Chowdhury T, McHugh K. Added value of abdominal cross-sectional imaging (CT or MRI) in staging of Wilms' tumours. Clin Radiol. 2013 Jan;68(1):16-20. doi: 10.1016/j.crad.2012.05.006. Epub 2012 Aug 11. </ref>
Case courtesy of Dr Jeremy Jones
[[Image:Wilms Tumor CTScan.gif|frame|left|[[Computed tomography|CT Scan]] of 11 cm '''Wilms' tumor''' of left kidney in 13 month old patient.]]
]]
<br clear="left"/>
[[File:Wilms-tumour-4.jpg|center|thumb|300x300px|Wilms tumor - axial view
source: Radiopedia - Case courtesy of Dr G Balachandran.<ref>Case courtesy of Dr G Balachandran, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/10250">rID: 10250</a></ref>
]]


==References==
==References==
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[[Category:Pediatrics]]
[[Category:Pediatrics]]
[[Category:Hematology]]
[[Category:Hematology]]
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Latest revision as of 15:24, 16 July 2018


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Sargun Singh Walia M.B.B.S.[2]

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Overview

Abdominal CT scan may be helpful in the diagnosis of Wilms tumor.Findings on CT scan which can be suggestive of Wilms tumor include soft-tissue density masses, areas of calcification (~10%) and fat-density regions. CT is better than ultrasonography in detecting small lesions of tumor. CT scan of the chest can be helpful to diagnose lung metastasis.

CT scan

  • Abdominal CT scan may be helpful in the diagnosis of Wilms tumor. Findings on CT scan suggestive of Wilms tumor include:[1][2][3]
    • Heterogeneous soft-tissue density masses
    • These masses have frequent areas of calcification (~10%) and fat-density regions
    • Lymph node metastasis
    • Invasion of surrounding organs
    • Thrombus in or occlusion of the renal vein and/or the inferior vena cava
    • Abdominal lymph nodes and contralateral involvement
    • Estimate tumor size and volume and to plan surgical management
    • Determine stage based on tumor size and structures involved
CT abdomen showing Wilms tumor Source:Radiopedia Case courtesy of Dr Jeremy Jones,[4]


Wilms tumor - coronal view source: radiopedia[5] Case courtesy of Dr Jeremy Jones
Wilms tumor - axial view source: Radiopedia - Case courtesy of Dr G Balachandran.[6]

References

  1. Cahan LD (1985). "Failure of encephalo-duro-arterio-synangiosis procedure in moyamoya disease". Pediatr Neurosci. 12 (1): 58–62. PMID 4080660.
  2. Wilms tumour. Dr Tim Luijkx and Dr Frank Gaillard et al. Radiopaedia.org 2015.http://radiopaedia.org/articles/wilms-tumour
  3. Gow KW, Roberts IF, Jamieson DH, Bray H, Magee JF, Murphy JJ (May 2000). "Local staging of Wilms' tumor--computerized tomography correlation with histological findings". J. Pediatr. Surg. 35 (5): 677–9. doi:10.1053/jpsu.2000.5941. PMID 10813321.
  4. https://radiopaedia.org/cases/8084
  5. Case courtesy of Dr Jeremy Jones, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/8084">rID: 8084</a>
  6. Case courtesy of Dr G Balachandran, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/10250">rID: 10250</a>

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