21-hydroxylase deficiency secondary prevention: Difference between revisions
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{{ | {{21-hydroxylase deficiency}} | ||
{{CMG}} {{AE}} {{ | {{CMG}}; {{AE}}{{MJ}} | ||
==Overview== | ==Overview== | ||
Continued monitoring of hormone balance and careful readjustment of [[glucocorticoid]] dose is helpful in controlling [[fertility]]. | Continued monitoring of hormone balance and careful readjustment of [[glucocorticoid]] dose is helpful in controlling [[fertility]] and preventing [[adrenal crisis]] in patient with 21-hydroxylase deficiency. | ||
==Secondary Prevention== | ==Secondary Prevention== | ||
===Preventing hyperandrogenism and optimizing fertility=== | ===Preventing hyperandrogenism and optimizing fertility=== | ||
Continued monitoring of hormone balance and careful | Continued monitoring of hormone balance and careful adjustment of [[glucocorticoid]] dose is helpful in controlling [[infertility]]. In general, women with 21-hydroxylase deficiency have a lower fertility rate.<ref name="pmid24083158">{{cite journal |vauthors=Mnif MF, Kamoun M, Kacem FH, Mnif F, Charfi N, Naceur BB, Rekik N, Abid M |title=Reproductive outcomes of female patients with congenital adrenal hyperplasia due to 21-hydroxylase defi ciency |journal=Indian J Endocrinol Metab |volume=17 |issue=5 |pages=790–3 |year=2013 |pmid=24083158 |pmc=3784860 |doi=10.4103/2230-8210.117196 |url=}}</ref> | ||
===Preventing adrenal crisis=== | ===Preventing adrenal crisis=== | ||
To prevent adrenal crisis, all | To prevent [[adrenal crisis]], all patients taking [[glucocorticoids]] replacement should take bolus dose of [[glucocorticoids]] during severe illness, surgery and severe exhaustion. | ||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{ | {{WH}} | ||
{{ | {{WS}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Pediatrics]] | [[Category:Pediatrics]] | ||
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[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
[[Category:Intersexuality]] | [[Category:Intersexuality]] | ||
[[Category:Medicine]] | |||
[[Category: Up-To-Date]] | |||
Latest revision as of 15:27, 24 July 2020
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21-hydroxylase deficiency Microchapters |
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Differentiating 21-Hydroxylase Deficiency from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]
Overview
Continued monitoring of hormone balance and careful readjustment of glucocorticoid dose is helpful in controlling fertility and preventing adrenal crisis in patient with 21-hydroxylase deficiency.
Secondary Prevention
Preventing hyperandrogenism and optimizing fertility
Continued monitoring of hormone balance and careful adjustment of glucocorticoid dose is helpful in controlling infertility. In general, women with 21-hydroxylase deficiency have a lower fertility rate.[1]
Preventing adrenal crisis
To prevent adrenal crisis, all patients taking glucocorticoids replacement should take bolus dose of glucocorticoids during severe illness, surgery and severe exhaustion.
References
- ↑ Mnif MF, Kamoun M, Kacem FH, Mnif F, Charfi N, Naceur BB, Rekik N, Abid M (2013). "Reproductive outcomes of female patients with congenital adrenal hyperplasia due to 21-hydroxylase defi ciency". Indian J Endocrinol Metab. 17 (5): 790–3. doi:10.4103/2230-8210.117196. PMC 3784860. PMID 24083158.