Angiomyolipoma differential diagnosis: Difference between revisions

Latest revision as of 13:17, 6 November 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2],Rekha, M.D.

Overview

Angiomyolipoma must be differentiated from retroperitoneal liposarcoma, adrenal myelolipoma, and renal cell carcinoma.^[1]^[2]

Differentiating Angiomyolipoma from other Diseases

Angiomyolipoma must be differentiated from the following:^[1]^[3]^[4]^[5]^[6]


Differential diagnosis	Characteristic features of the differential diagnosis

Retroperitoneal liposarcoma	Presence of a large vessel extending into the renal cortex suggestive of angiomyolipoma; liposarcoma is hypovascular^[7] Renal parenchymal defect at the site of tumor contact favors exophytic angiomyolipoma- claw sign Calcifications suggest liposarcoma
Renal cell carcinoma	May contain fat^[8] Lipid necrosis Osseous metaplasia
Oncocytoma	May contain fat
Wilm's tumor	May contain fat
Retroperitoneal sarcoma	Liposarcoma Leiomyosarcoma
Renal cell carcinoma	Sarcomatoid differentiation
Renal leiomyoma	Very rare Desmin +ve HMB-45 -ve
Perirenal fat entrapment	Renal junctional parenchymal defect
Adrenal myelolipoma	Fat in renal parenchyma

References

↑ ^1.0 ^1.1 Patil, PA.; McKenney, JK.; Trpkov, K.; Hes, O.; Montironi, R.; Scarpelli, M.; Nesi, G.; Aron, M.; Sangoi, AR. (2014). "Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm". Am J Surg Pathol. doi:10.1097/PAS.0000000000000354. PMID 25517956. Unknown parameter |month= ignored (help)
↑ Renal angiomyolipoma differential diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma
↑ N. Azumi, J. Curtis, R. L. Kempson & M. R. Hendrickson (1987). "Atypical and malignant neoplasms showing lipomatous differentiation. A study of 111 cases". The American journal of surgical pathology. 11 (3): 161–183. PMID 3826477. Unknown parameter |month= ignored (help)
↑ Emily Z. Keung, Jason L. Hornick, Monica M. Bertagnolli, Elizabeth H. Baldini & Chandrajit P. Raut (2014). "Predictors of outcomes in patients with primary retroperitoneal dedifferentiated liposarcoma undergoing surgery". Journal of the American College of Surgeons. 218 (2): 206–217. doi:10.1016/j.jamcollsurg.2013.10.009. PMID 24315890. Unknown parameter |month= ignored (help)
↑ Khin Thway, Robin L. Jones, Jonathan Noujaim, Shane Zaidi, Aisha B. Miah & Cyril Fisher (2016). "Dedifferentiated Liposarcoma: Updates on Morphology, Genetics, and Therapeutic Strategies". Advances in anatomic pathology. 23 (1): 30–40. doi:10.1097/PAP.0000000000000101. PMID 26645460. Unknown parameter |month= ignored (help)
↑ Cohen AJ, Li FP, Berg S, Marchetto DJ, Tsai S, Jacobs SC; et al. (1979). "Hereditary renal-cell carcinoma associated with a chromosomal translocation". N Engl J Med. 301 (11): 592–5. doi:10.1056/NEJM197909133011107. PMID 470981.
↑ Kate Lynn J. Bill, Lucia Casadei, Bethany C. Prudner, Hans Iwenofu, Anne M. Strohecker & Raphael E. Pollock (2016). "Liposarcoma: molecular targets and therapeutic implications". Cellular and molecular life sciences : CMLS. 73 (19): 3711–3718. doi:10.1007/s00018-016-2266-2. PMID 27173057. Unknown parameter |month= ignored (help)
↑ Cohen HT, McGovern FJ (2005). "Renal-cell carcinoma". N Engl J Med. 353 (23): 2477–90. doi:10.1056/NEJMra043172. PMID 16339096.

Template:WikiDoc Sources

[pmid25517956-1] 1.0 ^1.1 Patil, PA.; McKenney, JK.; Trpkov, K.; Hes, O.; Montironi, R.; Scarpelli, M.; Nesi, G.; Aron, M.; Sangoi, AR. (2014). "Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm". Am J Surg Pathol. doi:10.1097/PAS.0000000000000354. PMID 25517956. Unknown parameter |month= ignored (help)

[aaa-2] Renal angiomyolipoma differential diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma

[3] N. Azumi, J. Curtis, R. L. Kempson & M. R. Hendrickson (1987). "Atypical and malignant neoplasms showing lipomatous differentiation. A study of 111 cases". The American journal of surgical pathology. 11 (3): 161–183. PMID 3826477. Unknown parameter |month= ignored (help)

[4] Emily Z. Keung, Jason L. Hornick, Monica M. Bertagnolli, Elizabeth H. Baldini & Chandrajit P. Raut (2014). "Predictors of outcomes in patients with primary retroperitoneal dedifferentiated liposarcoma undergoing surgery". Journal of the American College of Surgeons. 218 (2): 206–217. doi:10.1016/j.jamcollsurg.2013.10.009. PMID 24315890. Unknown parameter |month= ignored (help)

[5] Khin Thway, Robin L. Jones, Jonathan Noujaim, Shane Zaidi, Aisha B. Miah & Cyril Fisher (2016). "Dedifferentiated Liposarcoma: Updates on Morphology, Genetics, and Therapeutic Strategies". Advances in anatomic pathology. 23 (1): 30–40. doi:10.1097/PAP.0000000000000101. PMID 26645460. Unknown parameter |month= ignored (help)

[pmid470981-6] Cohen AJ, Li FP, Berg S, Marchetto DJ, Tsai S, Jacobs SC; et al. (1979). "Hereditary renal-cell carcinoma associated with a chromosomal translocation". N Engl J Med. 301 (11): 592–5. doi:10.1056/NEJM197909133011107. PMID 470981.

[7] Kate Lynn J. Bill, Lucia Casadei, Bethany C. Prudner, Hans Iwenofu, Anne M. Strohecker & Raphael E. Pollock (2016). "Liposarcoma: molecular targets and therapeutic implications". Cellular and molecular life sciences : CMLS. 73 (19): 3711–3718. doi:10.1007/s00018-016-2266-2. PMID 27173057. Unknown parameter |month= ignored (help)

[pmid16339096-8] Cohen HT, McGovern FJ (2005). "Renal-cell carcinoma". N Engl J Med. 353 (23): 2477–90. doi:10.1056/NEJMra043172. PMID 16339096.

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@@ Line 1: / Line 1: @@
 __NOTOC__
-{{Angiomyolipoma}}
+[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Angiomyolipoma]]
-{{CMG}} {{AE}}{{Faizan}}
+{{CMG}} {{AE}}{{Faizan}},{{Rekha}}
 ==Overview==
-[[Angiomyolipoma]] must be differentiated from [[retroperitoneal liposarcoma]], [[adrenal myelolipoma]], and [[renal cell carcinoma]].
+[[Angiomyolipoma]] must be differentiated from [[retroperitoneal liposarcoma]], [[adrenal myelolipoma]], and [[renal cell carcinoma]].<ref name="pmid25517956">{{Cite journal  | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume =  | issue =  | pages =  | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref><ref name="aaa"> Renal angiomyolipoma differential diagnosis. Dr Matt A. Morgan and Dr Behrang Amini et al. Radiopaedia 2015. http://radiopaedia.org/articles/renal-angiomyolipoma</ref>
-==Differential Diagnosis==
+==Differentiating Angiomyolipoma from other Diseases==
-Angiomyolipoma must be differentiated from the following:<ref name=pmid25517956>{{Cite journal  | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume =  | issue =  | pages =  | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref>
+[[Angiomyolipoma]] must be differentiated from the following:<ref name="pmid25517956">{{Cite journal  | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume =  | issue =  | pages =  | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref><ref>{{Cite journal
-{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
+ | author = [[N. Azumi]], [[J. Curtis]], [[R. L. Kempson]] & [[M. R. Hendrickson]]
+ | title = Atypical and malignant neoplasms showing lipomatous differentiation. A study of 111 cases
+ | journal = [[The American journal of surgical pathology]]
+ | volume = 11
+ | issue = 3
+ | pages = 161–183
+ | year = 1987
+ | month = March
+ | pmid = 3826477
+}}</ref><ref>{{Cite journal
+ | author = [[Emily Z. Keung]], [[Jason L. Hornick]], [[Monica M. Bertagnolli]], [[Elizabeth H. Baldini]] & [[Chandrajit P. Raut]]
+ | title = Predictors of outcomes in patients with primary retroperitoneal dedifferentiated liposarcoma undergoing surgery
+ | journal = [[Journal of the American College of Surgeons]]
+ | volume = 218
+ | issue = 2
+ | pages = 206–217
+ | year = 2014
+ | month = February
+ | doi = 10.1016/j.jamcollsurg.2013.10.009
+ | pmid = 24315890
+}}</ref><ref>{{Cite journal
+ | author = [[Khin Thway]], [[Robin L. Jones]], [[Jonathan Noujaim]], [[Shane Zaidi]], [[Aisha B. Miah]] & [[Cyril Fisher]]
+ | title = Dedifferentiated Liposarcoma: Updates on Morphology, Genetics, and Therapeutic Strategies
+ | journal = [[Advances in anatomic pathology]]
+ | volume = 23
+ | issue = 1
+ | pages = 30–40
+ | year = 2016
+ | month = January
+ | doi = 10.1097/PAP.0000000000000101
+ | pmid = 26645460
+}}</ref><ref name="pmid470981">{{cite journal| author=Cohen AJ, Li FP, Berg S, Marchetto DJ, Tsai S, Jacobs SC et al.| title=Hereditary renal-cell carcinoma associated with a chromosomal translocation. | journal=N Engl J Med | year= 1979 | volume= 301 | issue= 11 | pages= 592-5 | pmid=470981 | doi=10.1056/NEJM197909133011107 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=470981  }}</ref>
+{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px" align=center
 |valign=top|
 |+
@@ Line 17: / Line 49: @@
 :[[Retroperitoneal liposarcoma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Presence of a large vessel extending into the renal cortex suggestive of AML; liposarcoma is hypovascular
+*Presence of a large vessel extending into the renal cortex suggestive of [[angiomyolipoma]]; [[liposarcoma]] is hypovascular<ref>{{Cite journal
-*Renal parenchymal defect at the site of tumour contact favours exophytic angiomyolipoma- claw sign
+ | author = [[Kate Lynn J. Bill]], [[Lucia Casadei]], [[Bethany C. Prudner]], [[Hans Iwenofu]], [[Anne M. Strohecker]] & [[Raphael E. Pollock]]
-*[[Calcification]]s suggest liposarcoma
+ | title = Liposarcoma: molecular targets and therapeutic implications
+ | journal = [[Cellular and molecular life sciences : CMLS]]
+ | volume = 73
+ | issue = 19
+ | pages = 3711–3718
+ | year = 2016
+ | month = October
+ | doi = 10.1007/s00018-016-2266-2
+ | pmid = 27173057
+}}</ref>
+*Renal [[Parenchyma|parenchymal]] defect at the site of [[tumor]] contact favors exophytic [[angiomyolipoma]]- claw sign
+*[[Calcification]]s suggest [[liposarcoma]]
+[[file:Retroperitoneal-liposarcoma-3.jpg | 200px]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:[[Renal cell carcinoma]] ([[RCC]])
+:[[Renal cell carcinoma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*May contain fat: lipid necrosis or osseous metaplasia
+*May contain fat<ref name="pmid16339096">{{cite journal| author=Cohen HT, McGovern FJ| title=Renal-cell carcinoma. | journal=N Engl J Med | year= 2005 | volume= 353 | issue= 23 | pages= 2477-90 | pmid=16339096 | doi=10.1056/NEJMra043172 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16339096  }}</ref>
+*Lipid [[necrosis]]
+*Osseous [[metaplasia]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
@@ Line 51: / Line 98: @@
 | style="padding: 5px 5px; background: #F5F5F5;" |
 *Very rare
-*Desmin +ve
+*[[Desmin]] +ve
-*HMB-45 -ve
+*[[HMB-45]] -ve
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
@@ Line 58: / Line 105: @@
 | style="padding: 5px 5px; background: #F5F5F5;" |
 *Renal junctional parenchymal defect
+|-
+| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
+:Adrenal myelolipoma
+| style="padding: 5px 5px; background: #F5F5F5;" |
+*Fat in renal parenchyma
+[[file:Adrenal-myelolipoma.jpg | 200px]]
 |-
 |}
@@ Line 67: / Line 120: @@
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Vascular medicine]]

Angiomyolipoma differential diagnosis: Difference between revisions

Latest revision as of 13:17, 6 November 2019

Overview

Differentiating Angiomyolipoma from other Diseases

References

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