Zollinger-Ellison syndrome ultrasound: Difference between revisions
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==Overview== | ==Overview== | ||
Abdominal [[ultrasound]] may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by [[gastrinoma]].<ref name="HarveyPasieka2012">{{cite journal|last1=Harvey|first1=Adrian|last2=Pasieka|first2=Janice L.|last3=Al-Bisher|first3=Hassan|last4=Dixon|first4=Elijah|title=Primary Hepatic Gastrinoma Causing Zollinger-Ellison Syndrome: A Rare and Challenging Diagnosis|journal=Cancers|volume=4|issue=4|year=2012|pages=130–140|issn=2072-6694|doi=10.3390/cancers4010130}}</ref> | Abdominal [[ultrasound]] may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by [[gastrinoma]].<ref name="HarveyPasieka2012">{{cite journal|last1=Harvey|first1=Adrian|last2=Pasieka|first2=Janice L.|last3=Al-Bisher|first3=Hassan|last4=Dixon|first4=Elijah|title=Primary Hepatic Gastrinoma Causing Zollinger-Ellison Syndrome: A Rare and Challenging Diagnosis|journal=Cancers|volume=4|issue=4|year=2012|pages=130–140|issn=2072-6694|doi=10.3390/cancers4010130}}</ref>. [[Ultrasonography]] can detect [[gastrinoma]]<nowiki/>s in 30%. [[Endoscopic]] ultrasonography (EUS) is a highly [[Sensitivity (tests)|sensitive]] and [[specificity|specific]] procedure for the localization of [[pancreatic]] endocrine tumors and [[duodenal]] as well as [[pancreatic]] gastrinomas. | ||
==Abdominal Ultrasound== | ==Abdominal Ultrasound== | ||
*I<nowiki/>n 30% of cases [[Ultrasonography]] can detect [[gastrinoma]]<nowiki/>s and the detection rates are better for lesions greater than 3 cm in diameter and are poor for lesions smaller than 1 cm. <ref name="pmid1994415">{{cite journal| author=London JF, Shawker TH, Doppman JL, Frucht HH, Vinayek R, Stark HA et al.| title=Zollinger-Ellison syndrome: prospective assessment of abdominal US in the localization of gastrinomas. | journal=Radiology | year= 1991 | volume= 178 | issue= 3 | pages= 763-7 | pmid=1994415 | doi=10.1148/radiology.178.3.1994415 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1994415 }} </ref> | |||
*[[Endoscopic]] ultrasonography (EUS) is a highly [[Sensitivity (tests)|sensitive]] and [[specificity|specific]] procedure for the localization of [[pancreatic]] [[neuroendocrine tumors]] and should be considered for the preoperative localization of such tumors once the clinical and laboratory diagnosis has been established. <ref name="pmid1317506">{{cite journal| author=Rösch T, Lightdale CJ, Botet JF, Boyce GA, Sivak MV, Yasuda K et al.| title=Localization of pancreatic endocrine tumors by endoscopic ultrasonography. | journal=N Engl J Med | year= 1992 | volume= 326 | issue= 26 | pages= 1721-6 | pmid=1317506 | doi=10.1056/NEJM199206253262601 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1317506 }} </ref> | |||
*[[Endoscopy]] or EUS should also be performed when a [[gastrinoma]] is suspected in order to identify duodenal as well as [[pancreatic]] [[gastrinomas]], especially when multiple lesions are suspected as in [[MEN 1]]. <ref name="pmid11762360">{{cite journal| author=Tomassetti P, Migliori M, Lalli S, Campana D, Tomassetti V, Corinaldesi R| title=Epidemiology, clinical features and diagnosis of gastroenteropancreatic endocrine tumours. | journal=Ann Oncol | year= 2001 | volume= 12 Suppl 2 | issue= | pages= S95-9 | pmid=11762360 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11762360 }} </ref> <ref name="pmid9113315">{{cite journal| author=Jensen RT| title=Gastrointestinal endocrine tumours. Gastrinoma. | journal=Baillieres Clin Gastroenterol | year= 1996 | volume= 10 | issue= 4 | pages= 603-43 | pmid=9113315 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9113315 }} </ref> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Latest revision as of 16:47, 11 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Abdominal ultrasound may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by gastrinoma.[1]. Ultrasonography can detect gastrinomas in 30%. Endoscopic ultrasonography (EUS) is a highly sensitive and specific procedure for the localization of pancreatic endocrine tumors and duodenal as well as pancreatic gastrinomas.
Abdominal Ultrasound
- In 30% of cases Ultrasonography can detect gastrinomas and the detection rates are better for lesions greater than 3 cm in diameter and are poor for lesions smaller than 1 cm. [2]
- Endoscopic ultrasonography (EUS) is a highly sensitive and specific procedure for the localization of pancreatic neuroendocrine tumors and should be considered for the preoperative localization of such tumors once the clinical and laboratory diagnosis has been established. [3]
- Endoscopy or EUS should also be performed when a gastrinoma is suspected in order to identify duodenal as well as pancreatic gastrinomas, especially when multiple lesions are suspected as in MEN 1. [4] [5]
References
- ↑ Harvey, Adrian; Pasieka, Janice L.; Al-Bisher, Hassan; Dixon, Elijah (2012). "Primary Hepatic Gastrinoma Causing Zollinger-Ellison Syndrome: A Rare and Challenging Diagnosis". Cancers. 4 (4): 130–140. doi:10.3390/cancers4010130. ISSN 2072-6694.
- ↑ London JF, Shawker TH, Doppman JL, Frucht HH, Vinayek R, Stark HA; et al. (1991). "Zollinger-Ellison syndrome: prospective assessment of abdominal US in the localization of gastrinomas". Radiology. 178 (3): 763–7. doi:10.1148/radiology.178.3.1994415. PMID 1994415.
- ↑ Rösch T, Lightdale CJ, Botet JF, Boyce GA, Sivak MV, Yasuda K; et al. (1992). "Localization of pancreatic endocrine tumors by endoscopic ultrasonography". N Engl J Med. 326 (26): 1721–6. doi:10.1056/NEJM199206253262601. PMID 1317506.
- ↑ Tomassetti P, Migliori M, Lalli S, Campana D, Tomassetti V, Corinaldesi R (2001). "Epidemiology, clinical features and diagnosis of gastroenteropancreatic endocrine tumours". Ann Oncol. 12 Suppl 2: S95–9. PMID 11762360.
- ↑ Jensen RT (1996). "Gastrointestinal endocrine tumours. Gastrinoma". Baillieres Clin Gastroenterol. 10 (4): 603–43. PMID 9113315.