Brain abscess natural history, complications and prognosis: Difference between revisions
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{{CMG}} | {{CMG}}; {{AE}} {{FH}} | ||
{{Brain abscess}} | {{Brain abscess}} | ||
==Overview== | ==Overview== | ||
If left untreated, a brain abscess can be fatal. Common complications include [[abscess]] rupture, [[hydrocephalus]], and [[brain herniation]]. With treatment, the mortality rate decreases to about 10% of the population. | |||
==Natural History== | |||
If left untreated, a brain abscess is almost always fatal. If there is an abscess rupture into the ventricular system, [[ventriculitis]] can result.<ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref> Early detection and treatment is preferential. After surgery, some patients can experience long-term neurological problems.<ref>Nath A. Brain abscess and parameningeal infections. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 438.</ref> | |||
==Complications== | ==Complications== | ||
Common complications | Common complications include:<ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref> | ||
* [[ | * [[Abscess]] rupture | ||
* [[Hydrocephalus]] | |||
* [[Brain herniation]] | * [[Brain herniation]] | ||
==Prognosis== | ==Prognosis== | ||
While the mortality rate was 40% in 1960, it has dropped down to 15% within the past decade alone. 70% of patients with brain abscesses have a good outcome, rarely with minimal neurological [[sequelae]]. <ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref> | With treatment, the mortality rate is about 10% to 30%. While the mortality rate was 40% in 1960, it has dropped down to 15% within the past decade alone. About 70% of patients with brain abscesses have a good outcome, rarely with minimal neurological [[sequelae]].<ref name="pmid25075836">{{cite journal| author=Brouwer MC, Tunkel AR, McKhann GM, van de Beek D| title=Brain abscess. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 5 | pages= 447-56 | pmid=25075836 | doi=10.1056/NEJMra1301635 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25075836 }} </ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Neurology]] | [[Category:Neurology]] | ||
[[Category:Neurosurgery]] | [[Category:Neurosurgery]] | ||
[[Category: | [[Category:Emergency medicine]] | ||
Latest revision as of 20:40, 29 July 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farwa Haideri [2]
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Overview
If left untreated, a brain abscess can be fatal. Common complications include abscess rupture, hydrocephalus, and brain herniation. With treatment, the mortality rate decreases to about 10% of the population.
Natural History
If left untreated, a brain abscess is almost always fatal. If there is an abscess rupture into the ventricular system, ventriculitis can result.[1] Early detection and treatment is preferential. After surgery, some patients can experience long-term neurological problems.[2]
Complications
Common complications include:[1]
- Abscess rupture
- Hydrocephalus
- Brain herniation
Prognosis
With treatment, the mortality rate is about 10% to 30%. While the mortality rate was 40% in 1960, it has dropped down to 15% within the past decade alone. About 70% of patients with brain abscesses have a good outcome, rarely with minimal neurological sequelae.[1]
References
- ↑ 1.0 1.1 1.2 Brouwer MC, Tunkel AR, McKhann GM, van de Beek D (2014). "Brain abscess". N Engl J Med. 371 (5): 447–56. doi:10.1056/NEJMra1301635. PMID 25075836.
- ↑ Nath A. Brain abscess and parameningeal infections. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 438.