Anaplastic large cell lymphoma laboratory findings: Difference between revisions
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{{Anaplastic large cell lymphoma}} | {{Anaplastic large cell lymphoma}} | ||
{{CMG}}; {{AE}} {{AS}}, {{kakbar}}; {{GRR}} {{Nat}} | |||
==Overview== | |||
===Laboratory | Laboratory tests for anaplastic large cell lymphoma include [[complete blood count]] (CBC), blood chemistry studies, [[flow cytometry]], [[FISH]], [[immunohistochemistry]], and [[immunophenotyping]]. | ||
*[[Anemia]] | ==Laboratory Tests== | ||
*[[Thrombocytopenia]] | Laboratory tests for anaplastic large cell lymphoma include:<ref name="ALK+/ALK-">{{cite web|url=http://www.bloodjournal.org/content/111/12/5496?sso-checked=true|title=ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project}}</ref><ref name = hindawi> Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma. Hindawi Publishing Corporation. http://www.hindawi.com/journals/ah/2012/529572/#B1 Accessed on October 13, 2015</ref> | ||
*Increased [[LDH]] | * [[Complete blood count]] (CBC) | ||
:* [[Anemia]] | |||
:* [[Thrombocytopenia]] | |||
* Blood chemistry studies | |||
:* Increased [[LDH]] | |||
* [[Flow cytometry]] | |||
* Fluorescence in situ hybridization ([[FISH]]) | |||
:* Negative for the Epstein-Barr virus ([[EBV]]) | |||
* [[Immunohistochemistry]] | |||
:* Negative for human herpes virus-8 (HHV8) | |||
* Immunophenotyping | |||
:* Strongly immunoreactive for [[CD30]], Anaplastic lymphoma kinase (ALK), EMA, and [[vimentin]] | |||
:* Negative for AE1/AE3, CK20, CK7, CK5/6, P63, [[SMA]], [[HMB-45]], pan-Melan, S-100, Myo D1, [[synaptophysin]], [[CD56]], [[desmin]], [[CD15]], [[CD20]], Pax-5, and [[CD3]] | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Pathology]] | [[Category:Pathology]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Hematology]] | |||
[[Category:Immunology]] | |||
Latest revision as of 12:44, 11 April 2019
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Anaplastic large cell lymphoma Microchapters |
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Differentiating Anaplastic large cell lymphoma from other Diseases |
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Diagnosis |
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Anaplastic large cell lymphoma laboratory findings On the Web |
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Anaplastic large cell lymphoma laboratory findings in the news |
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Directions to Hospitals Treating Anaplastic large cell lymphoma |
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Risk calculators and risk factors for Anaplastic large cell lymphoma laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2], Kamal Akbar, M.D.[3]; Grammar Reviewer: Natalie Harpenau, B.S.[4]
Overview
Laboratory tests for anaplastic large cell lymphoma include complete blood count (CBC), blood chemistry studies, flow cytometry, FISH, immunohistochemistry, and immunophenotyping.
Laboratory Tests
Laboratory tests for anaplastic large cell lymphoma include:[1][2]
- Complete blood count (CBC)
- Blood chemistry studies
- Increased LDH
- Flow cytometry
- Fluorescence in situ hybridization (FISH)
- Negative for the Epstein-Barr virus (EBV)
- Negative for human herpes virus-8 (HHV8)
- Immunophenotyping
References
- ↑ "ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project".
- ↑ Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma. Hindawi Publishing Corporation. http://www.hindawi.com/journals/ah/2012/529572/#B1 Accessed on October 13, 2015