Chronic lymphocytic leukemia other diagnostic studies: Difference between revisions
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{{Chronic lymphocytic leukemia}} | {{Chronic lymphocytic leukemia}} | ||
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==Overview== | ==Overview== | ||
[[Bone marrow biopsy]] and [[cytogenetic tests]] may be helpful in the diagnosis of chronic lymphocytic leukemia. [[Karyotyping]] and [[fluorescent in situ hybridization]] detect any [[chromosomal]] [[mutations]] involved in the development of chronic lymphocytic leukemia. | |||
==Bone Marrow Biopsy== | |||
* [[Bone marrow biopsy]] and [[ | * [[Bone marrow biopsy]] and [[cytogenetic tests]] may be helpful in the diagnosis of chronic lymphocytic leukemia. Histopathological findings on biopsy can be found [[Chronic lymphocytic leukemia pathophysiology|'''here''']].<ref name="pmid25908509">{{cite journal| author=Hallek M| title=Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment. | journal=Am J Hematol | year= 2015 | volume= 90 | issue= 5 | pages= 446-60 | pmid=25908509 | doi=10.1002/ajh.23979 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25908509 }} </ref> | ||
[[ | ==Cytogenetic Tests== | ||
* '''[[Karyotyping]]''' | |||
:* Detects any [[chromosomal]] [[mutations]] among chronic lymphocytic leukemia patients. Common genetic mutations involved in the development of chronic lymphocytic leukemia can be found [[Chronic lymphocytic leukemia pathophysiology|'''here''']].<ref name="pmid25908509">{{cite journal| author=Hallek M| title=Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment. | journal=Am J Hematol | year= 2015 | volume= 90 | issue= 5 | pages= 446-60 | pmid=25908509 | doi=10.1002/ajh.23979 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25908509 }} </ref> | |||
* '''[[Fluorescent in situ hybridization]]''' | |||
:* Detects any [[chromosomal]] [[mutations]] occurring among chronic lymphocytic leukemia patients. Common genetic mutations involved in the development of chronic lymphocytic leukemia can be found [[Chronic lymphocytic leukemia pathophysiology|'''here''']]. | |||
'''[[Fluorescent in situ hybridization]]''' | |||
:* Detects any [[chromosomal]] [[mutations]] occurring | |||
==References== | ==References== | ||
{{reflist| | {{reflist|1}} | ||
{{Hematology}} | {{Hematology}} | ||
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Latest revision as of 01:26, 7 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Bone marrow biopsy and cytogenetic tests may be helpful in the diagnosis of chronic lymphocytic leukemia. Karyotyping and fluorescent in situ hybridization detect any chromosomal mutations involved in the development of chronic lymphocytic leukemia.
Bone Marrow Biopsy
- Bone marrow biopsy and cytogenetic tests may be helpful in the diagnosis of chronic lymphocytic leukemia. Histopathological findings on biopsy can be found here.[1]
Cytogenetic Tests
- Detects any chromosomal mutations among chronic lymphocytic leukemia patients. Common genetic mutations involved in the development of chronic lymphocytic leukemia can be found here.[1]
- Detects any chromosomal mutations occurring among chronic lymphocytic leukemia patients. Common genetic mutations involved in the development of chronic lymphocytic leukemia can be found here.
References
- ↑ 1.0 1.1 Hallek M (2015). "Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment". Am J Hematol. 90 (5): 446–60. doi:10.1002/ajh.23979. PMID 25908509.