Anaplastic large cell lymphoma physical examination: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Anaplastic large cell lymphoma}} | {{Anaplastic large cell lymphoma}} | ||
{{CMG}}; {{AE}} {{AS}} | {{CMG}}; {{AE}} {{AS}}, {{kakbar}}; {{GRR}} {{Nat}} | ||
==Overview== | ==Overview== | ||
Common physical examination findings of | Common physical examination findings of anaplastic large cell lymphoma include [[fever]], [[rash]], [[ulcer]], [[splenomegaly]], [[hepatomegaly]], chest tenderness, abdomen tenderness, bone tenderness, [[Lymphadenopathy|peripheral lymphadenopathy]], and [[Lymphadenopathy|central lymphadenopathy]]. | ||
===Temperature=== | ===Temperature=== | ||
* [[Fever]] is often present | * [[Fever]] is often present<ref name="pmid28652989">{{cite journal| author=de Campos FPF, Zerbini MCN, Felipe-Silva A, Simões AB, Lovisolo SM, da Fonseca LG et al.| title=Unusual clinical presentation of anaplastic large cell lymphoma. | journal=Autops Case Rep | year= 2014 | volume= 4 | issue= 1 | pages= 21-27 | pmid=28652989 | doi=10.4322/acr.2014.004 | pmc=5470561 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28652989 }} </ref><ref name="Al-AhmadMaertens2017">{{cite journal|last1=Al-Ahmad|first1=Selma|last2=Maertens|first2=Vincent|last3=Libeer|first3=Christophe|last4=Schelfhout|first4=Vera|last5=Vanhoenacker|first5=Filip|last6=Boeckx|first6=Nancy|last7=Vandevenne|first7=Marleen|title=The masquerading presentation of a systemic anaplastic large cell lymphoma, ALK positive: a case report and review of the literature|journal=Acta Clinica Belgica|volume=72|issue=6|year=2017|pages=454–460|issn=1784-3286|doi=10.1080/17843286.2017.1312057}}</ref> | ||
===Skin=== | ===Skin=== | ||
* [[Rash]] | * [[Rash]] <ref name="pmid27504444">{{cite journal| author=Tagami T, Alhalabi O, Ward N, Huang J| title=Paraneoplastic Dermatosis in a Patient with Anaplastic Large-Cell Lymphoma: Case Report and Literature Review. | journal=Dermatopathology (Basel) | year= 2016 | volume= 3 | issue= 2 | pages= 39-43 | pmid=27504444 | doi=10.1159/000445766 | pmc=4965535 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27504444 }} </ref> | ||
* [[Ulcer]] | * [[Ulcer]] | ||
===Neck=== | ===Neck=== | ||
* [[Lymphadenopathy|Cervical lymphadenopathy]] | * [[Lymphadenopathy|Cervical lymphadenopathy]]<ref name="pmid26770602">{{cite journal| author=Yang W, Zuo Y, Yang Y, Tao J, Hong J, Wu Z et al.| title=Pediatric anaplastic large cell lymphoma misdiagnosed as multiple organ abscesses: a case report and literature review. | journal=Int J Clin Exp Med | year= 2015 | volume= 8 | issue= 10 | pages= 19509-16 | pmid=26770602 | doi= | pmc=4694502 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26770602 }} </ref> | ||
===Thorax=== | ===Thorax=== | ||
* Thoracic masses suggestive of [[Lymphadenopathy|central lymphadenopathy]] | * Thoracic masses suggestive of [[Lymphadenopathy|central lymphadenopathy]]<ref name="pmid26770602">{{cite journal| author=Yang W, Zuo Y, Yang Y, Tao J, Hong J, Wu Z et al.| title=Pediatric anaplastic large cell lymphoma misdiagnosed as multiple organ abscesses: a case report and literature review. | journal=Int J Clin Exp Med | year= 2015 | volume= 8 | issue= 10 | pages= 19509-16 | pmid=26770602 | doi= | pmc=4694502 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26770602 }} </ref> | ||
* Chest tenderness | * Chest tenderness<ref name="pmid16361823">{{cite journal| author=Song HH, Baik GH, Kwon JH, Lee KS, Choi YH, Choi KC et al.| title=A case of primary gastric CD30-positive anaplastic large-cell lymphoma. | journal=J Korean Med Sci | year= 2005 | volume= 20 | issue= 6 | pages= 1062-5 | pmid=16361823 | doi=10.3346/jkms.2005.20.6.1062 | pmc=2779310 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16361823 }} </ref> | ||
===Abdomen=== | ===Abdomen=== | ||
* [[Abdominal mass]]es suggestive of [[Lymphadenopathy|central lymphadenopathy]] | * [[Abdominal mass]]es suggestive of [[Lymphadenopathy|central lymphadenopathy]] | ||
* [[Splenomegaly]] | * [[Splenomegaly]]<ref name="pmid28652989">{{cite journal| author=de Campos FPF, Zerbini MCN, Felipe-Silva A, Simões AB, Lovisolo SM, da Fonseca LG et al.| title=Unusual clinical presentation of anaplastic large cell lymphoma. | journal=Autops Case Rep | year= 2014 | volume= 4 | issue= 1 | pages= 21-27 | pmid=28652989 | doi=10.4322/acr.2014.004 | pmc=5470561 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28652989 }} </ref> | ||
* [[Hepatomegaly]] | * [[Hepatomegaly]] <ref name="pmid23451333">{{cite journal| author=Jiménez Fuertes M, Costa Navarro D, Montalvá Orón EM, López-Andújar R, de Juan Burgueño M, Mir Pallardó J| title=Primary hepatic anaplastic large cell ki-1 lymphoma and celiac disease: a casual association? | journal=J Gastrointest Oncol | year= 2013 | volume= 4 | issue= 1 | pages= 109-13 | pmid=23451333 | doi=10.3978/j.issn.2078-6891.2012.059 | pmc=3562637 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23451333 }} </ref> | ||
* Abdomen tenderness | * Abdomen tenderness <ref name="pmid16361823">{{cite journal| author=Song HH, Baik GH, Kwon JH, Lee KS, Choi YH, Choi KC et al.| title=A case of primary gastric CD30-positive anaplastic large-cell lymphoma. | journal=J Korean Med Sci | year= 2005 | volume= 20 | issue= 6 | pages= 1062-5 | pmid=16361823 | doi=10.3346/jkms.2005.20.6.1062 | pmc=2779310 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16361823 }} </ref> | ||
===Extremities=== | ===Extremities=== | ||
* [[Lymphadenopathy|Peripheral lymphadenopathy]] | * [[Lymphadenopathy|Peripheral lymphadenopathy]] | ||
* Bone tenderness | * Bone tenderness<ref name="pmid27729639">{{cite journal| author=Kim KH, Jung YH, Han CW, Woo IS, Son JH| title=A case of Primary Bone Anaplastic Large Cell Lymphoma. | journal=Am J Case Rep | year= 2016 | volume= 17 | issue= | pages= 734-738 | pmid=27729639 | doi= | pmc=5063430 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27729639 }} </ref> | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Hematology]] | |||
[[Category:Immunology]] | |||
Latest revision as of 12:44, 11 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2], Kamal Akbar, M.D.[3]; Grammar Reviewer: Natalie Harpenau, B.S.[4]
Overview
Common physical examination findings of anaplastic large cell lymphoma include fever, rash, ulcer, splenomegaly, hepatomegaly, chest tenderness, abdomen tenderness, bone tenderness, peripheral lymphadenopathy, and central lymphadenopathy.
Temperature
Skin
Neck
Thorax
- Thoracic masses suggestive of central lymphadenopathy[4]
- Chest tenderness[5]
Abdomen
- Abdominal masses suggestive of central lymphadenopathy
- Splenomegaly[1]
- Hepatomegaly [6]
- Abdomen tenderness [5]
Extremities
- Peripheral lymphadenopathy
- Bone tenderness[7]
References
- ↑ 1.0 1.1 de Campos FPF, Zerbini MCN, Felipe-Silva A, Simões AB, Lovisolo SM, da Fonseca LG; et al. (2014). "Unusual clinical presentation of anaplastic large cell lymphoma". Autops Case Rep. 4 (1): 21–27. doi:10.4322/acr.2014.004. PMC 5470561. PMID 28652989.
- ↑ Al-Ahmad, Selma; Maertens, Vincent; Libeer, Christophe; Schelfhout, Vera; Vanhoenacker, Filip; Boeckx, Nancy; Vandevenne, Marleen (2017). "The masquerading presentation of a systemic anaplastic large cell lymphoma, ALK positive: a case report and review of the literature". Acta Clinica Belgica. 72 (6): 454–460. doi:10.1080/17843286.2017.1312057. ISSN 1784-3286.
- ↑ Tagami T, Alhalabi O, Ward N, Huang J (2016). "Paraneoplastic Dermatosis in a Patient with Anaplastic Large-Cell Lymphoma: Case Report and Literature Review". Dermatopathology (Basel). 3 (2): 39–43. doi:10.1159/000445766. PMC 4965535. PMID 27504444.
- ↑ 4.0 4.1 Yang W, Zuo Y, Yang Y, Tao J, Hong J, Wu Z; et al. (2015). "Pediatric anaplastic large cell lymphoma misdiagnosed as multiple organ abscesses: a case report and literature review". Int J Clin Exp Med. 8 (10): 19509–16. PMC 4694502. PMID 26770602.
- ↑ 5.0 5.1 Song HH, Baik GH, Kwon JH, Lee KS, Choi YH, Choi KC; et al. (2005). "A case of primary gastric CD30-positive anaplastic large-cell lymphoma". J Korean Med Sci. 20 (6): 1062–5. doi:10.3346/jkms.2005.20.6.1062. PMC 2779310. PMID 16361823.
- ↑ Jiménez Fuertes M, Costa Navarro D, Montalvá Orón EM, López-Andújar R, de Juan Burgueño M, Mir Pallardó J (2013). "Primary hepatic anaplastic large cell ki-1 lymphoma and celiac disease: a casual association?". J Gastrointest Oncol. 4 (1): 109–13. doi:10.3978/j.issn.2078-6891.2012.059. PMC 3562637. PMID 23451333.
- ↑ Kim KH, Jung YH, Han CW, Woo IS, Son JH (2016). "A case of Primary Bone Anaplastic Large Cell Lymphoma". Am J Case Rep. 17: 734–738. PMC 5063430. PMID 27729639.