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{{Essential thrombocytosis}}
{{Essential thrombocytosis}}
{{CMG}}
{{CMG}}{{AE}} {{STM}}


==Overview==
==Overview==
Essential or primary thrombocytosis as the name suggests does not have an underlying cause. But, rarely a familial form of the disease is inherited in an autosomal dominant fashion.
There is no classification system established for essential thrombocytosis. However, a familial form of essential thrombocytosis has been previously reported.<ref name="TrifaCucuianu2014">{{cite journal|last1=Trifa|first1=Adrian P.|last2=Cucuianu|first2=Andrei|last3=Popp|first3=Radu A.|title=Familial Essential Thrombocythemia Associated withMPLW515L Mutation in Father andJAK2V617F Mutation in Daughter|journal=Case Reports in Hematology|volume=2014|year=2014|pages=1–3|issn=2090-6560|doi=10.1155/2014/841787}}</ref>
 
==Classification==
*There is no classification system established for essential thrombocytosis. However, essential thrombocytosis may be broadly classified into two types:<ref name="TrifaCucuianu2014">{{cite journal|last1=Trifa|first1=Adrian P.|last2=Cucuianu|first2=Andrei|last3=Popp|first3=Radu A.|title=Familial Essential Thrombocythemia Associated withMPLW515L Mutation in Father andJAK2V617F Mutation in Daughter|journal=Case Reports in Hematology|volume=2014|year=2014|pages=1–3|issn=2090-6560|doi=10.1155/2014/841787}}</ref> 
**[[Sporadic]]
***The majority of cases remain sporadic.
**[[Genetic]]
***Inheritance is in an autosomal dominant fashion with incomplete penetrance.  


==References==
==References==

Latest revision as of 14:42, 6 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

There is no classification system established for essential thrombocytosis. However, a familial form of essential thrombocytosis has been previously reported.[1]

Classification

  • There is no classification system established for essential thrombocytosis. However, essential thrombocytosis may be broadly classified into two types:[1]
    • Sporadic
      • The majority of cases remain sporadic.
    • Genetic
      • Inheritance is in an autosomal dominant fashion with incomplete penetrance.

References

  1. 1.0 1.1 Trifa, Adrian P.; Cucuianu, Andrei; Popp, Radu A. (2014). "Familial Essential Thrombocythemia Associated withMPLW515L Mutation in Father andJAK2V617F Mutation in Daughter". Case Reports in Hematology. 2014: 1–3. doi:10.1155/2014/841787. ISSN 2090-6560.


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