Sandbox:DDx HEENT: Difference between revisions

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* 30-50 yo Caucasian women
* Anemia and lymphopenia
* Ionizing radiation exposure
* Eosinophilia and neutrophiliae
* Positive family history
* Positive warm-agglutinin  antibodies
* Asymptomatic painless neck nodule
* Elevated LDH and creatinine concentration
 
 
* Elevated thyroglobulin level
* HBME-1 stain +ve and ATP5E stain +ve
 
 
* Orphan Annie eye and Psammoma bodies
* Unencapsulated multifocal tumor lesions
* Positive lymphatic spread
 
 
* Solitary mass with irregular borders and increased vascularity on U/S
* Located at the subcapsular region
* Small punctate regions of echogenicity due to calcification
* Lymph node metastases present
 
* RAS oncogene activation
* PAX8-PPAR gamma 1 genes rearrangement

Latest revision as of 20:51, 4 November 2015

  • Anemia and lymphopenia
  • Eosinophilia and neutrophiliae
  • Positive warm-agglutinin antibodies
  • Elevated LDH and creatinine concentration