Sandbox:DDx HEENT: Difference between revisions

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40-60 yo women
* Anemia and lymphopenia
 
* Eosinophilia and neutrophiliae
 
* Positive warm-agglutinin  antibodies
* Painless thyroid nodule
* Elevated LDH and creatinine concentration
* May have bone pain or respiratory symptoms
 
 
* Elevated thyroglobulin level
* HBME-1 stain +ve and ATP5E stain +ve
 
 
* Orphan Annie eye and Psammoma bodies
* Unencapsulated multifocal tumor lesions
* Positive lymphatic spread
 
 
* Solitary mass with irregular borders and increased vascularity on U/S
* Lytic bone lesions or multiple lung masses due to hematogenous spread
* Rare lymph node metastases
 
* RAS oncogene activation
* PAX8-PPAR gamma 1 genes rearrangement

Latest revision as of 20:51, 4 November 2015

  • Anemia and lymphopenia
  • Eosinophilia and neutrophiliae
  • Positive warm-agglutinin antibodies
  • Elevated LDH and creatinine concentration
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