Sandbox:DDx HEENT: Difference between revisions

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* 65 yo women
* Anemia and lymphopenia
* Rapidly enlarging neck mass
* Eosinophilia and neutrophiliae
* Neck pain, dyspnea, dysphagia, and hoarseness
* Positive warm-agglutinin  antibodies
* Constitutional symptoms
* Elevated LDH and creatinine concentration
 
* Tender hard nodular goiter
* Extensive lymphadenopathy
 
* Painless thyroid nodule
* Neck lymphadenopathy
 
* Elevated calcitonin
* Elevated chromogranin
* Elevated CEA
 
* Multiple hypoechoegenic lesions on U/s
* Lymph node calcifications
* Liver metastasis
* Nested cellular pattern separated by delicate vascular septa
* Polygonal cells, round nuclie with coarse chromatin, granular cytoplasm, surrounded by amyloid deposits
* Vascular stroma with hemorrhage, edema, and coarse calcification
* C-cell hyperplasia may be present
 
 
* RET proto-oncogene

Latest revision as of 20:51, 4 November 2015

  • Anemia and lymphopenia
  • Eosinophilia and neutrophiliae
  • Positive warm-agglutinin antibodies
  • Elevated LDH and creatinine concentration
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