Sandbox: DDx Kidney mass: Difference between revisions

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* 50-70 yo males
* Asymptomatic
* Incidental finding


* Palpable flank mass
* Fever, chills, night sweats, and abdominal pain
* Hematuria, pallor, and weight loss




* Papillary foamy macrophages
* Costovertebral tenderness
* Intracellular hemosiderin
* Size 7 cm




* Heterogeneous, multifocal, well-circumscribed, mass on CT
* Elevated WBC count
* Less intense contrast enhancement
* Elevated ESR and CRP
* Calcification


* Well defined hypoechoic area within the corticomedullary parenchyma on U/S
* Well defined mass of low attenuation with a thick, irregular wall or pseudocapsule on CT


* Papillary fibrovascular cores
* Not applicable
* Cuboidal cells with a finely granular cytoplasm
 
* Longitudinal nuclear groove
Angiosarcoma
* Hyaline globules present
* Distinct fibrous capsule


* Trisomy 7
* Trisomy 17




==Nonmalignant causes==
==Nonmalignant causes==
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying

Latest revision as of 20:52, 9 November 2015

  • Fever, chills, night sweats, and abdominal pain
  • Hematuria, pallor, and weight loss


  • Costovertebral tenderness


  • Elevated WBC count
  • Elevated ESR and CRP
  • Well defined hypoechoic area within the corticomedullary parenchyma on U/S
  • Well defined mass of low attenuation with a thick, irregular wall or pseudocapsule on CT
  • Not applicable

Angiosarcoma


Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying