Intracerebral metastases other diagnostic studies: Difference between revisions
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{{Intracerebral metastases}} | {{Intracerebral metastases}} | ||
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==Overview== | |||
[[Brain biopsy]] is done to confirm the diagnosis of intracerebral metastases, if the type of primary tumor is unknown or the etiology of the brain abnormality is unknown.<ref name="Khuntia2015">{{cite journal|last1=Khuntia|first1=Deepak|title=Contemporary Review of the Management of Brain Metastasis with Radiation|journal=Advances in Neuroscience|volume=2015|year=2015|pages=1–13|issn=2356-6787|doi=10.1155/2015/372856}}</ref> Histopathological findings on biopsy of intracerebral metastases can be found [[Intracerebral metastases pathophysiology|'''here''']].<ref name=microscopicpathologyofintracerebralmetastasis1>Microscopic features of brain metastasis. Libre pathology 2015. http://librepathology.org/wiki/index.php/Brain_metastasis. Accessed on November 10, 2015</ref><ref name=micro2>Microscopic appearance of brain metastases. Dr Bruno Di Muzio and Dr Trent Orton et al. Radiopaedia 2015. http://radiopaedia.org/articles/brain-metastases. Accessed on November 10, 2015</ref> | |||
==Other Diagnostic Studies== | |||
*[[Brain biopsy]] is done to confirm the diagnosis of intracerebral metastases, if the type of primary tumor is unknown or the etiology of the brain abnormality is unknown.<ref name="Khuntia2015">{{cite journal|last1=Khuntia|first1=Deepak|title=Contemporary Review of the Management of Brain Metastasis with Radiation|journal=Advances in Neuroscience|volume=2015|year=2015|pages=1–13|issn=2356-6787|doi=10.1155/2015/372856}}</ref> | |||
*Histopathological findings on biopsy of intracerebral metastases can be found [[Intracerebral metastases pathophysiology|'''here''']].<ref name=microscopicpathologyofintracerebralmetastasis1>Microscopic features of brain metastasis. Libre pathology 2015. http://librepathology.org/wiki/index.php/Brain_metastasis. Accessed on November 10, 2015</ref><ref name=micro2>Microscopic appearance of brain metastases. Dr Bruno Di Muzio and Dr Trent Orton et al. Radiopaedia 2015. http://radiopaedia.org/articles/brain-metastases. Accessed on November 10, 2015</ref> | |||
*Biopsy may be of two types: [[craniotomy|open]] and [[stereotactic]]. | |||
*Indications for [[craniotomy|open biopsy]] and [[stereotactic|stereotactic biopsy]] are described below:<ref name="pmid15509821">{{cite journal| author=Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN| title=Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion. | journal=N Engl J Med | year= 2004 | volume= 351 | issue= 18 | pages= 1875-82 | pmid=15509821 | doi=10.1056/NEJMcpc049025 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15509821 }} </ref> | |||
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! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Type of biopsy}} | |||
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Indications}} | |||
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[[craniotomy|Open biopsy]] | |||
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*Surgically resectable masses | |||
*Lesions in accessible and relatively “silent” areas of the brain or in areas of the brain with a mild postoperative neurological deficit | |||
*Appearance consistent with [[tumor]] on the [[MRI]] | |||
*Large [[tumors]] exerting mass effect | |||
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[[Stereotactic|Stereotactic biopsy]] | |||
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*Deep-seated [[tumor]] that is not amenable to resection | |||
*Lesions in which the radiological and clinical findings are ambiguous | |||
*Diffuse or multiple lesions | |||
*Appearance that suggests a [[lymphoma]], which would not require resection | |||
*Change in the appearance of a previously diagnosed or treated [[tumor]] | |||
*Assessment of tumor after treatment (to distinguish between [[radiation|radiation necrosis]] and tumor recurrence) | |||
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==References== | ==References== | ||
Latest revision as of 20:24, 23 November 2015
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Intracerebral metastases Microchapters |
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Differentiating Intracerebral Metastases from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Brain biopsy is done to confirm the diagnosis of intracerebral metastases, if the type of primary tumor is unknown or the etiology of the brain abnormality is unknown.[1] Histopathological findings on biopsy of intracerebral metastases can be found here.[2][3]
Other Diagnostic Studies
- Brain biopsy is done to confirm the diagnosis of intracerebral metastases, if the type of primary tumor is unknown or the etiology of the brain abnormality is unknown.[1]
- Histopathological findings on biopsy of intracerebral metastases can be found here.[2][3]
- Biopsy may be of two types: open and stereotactic.
- Indications for open biopsy and stereotactic biopsy are described below:[4]
| Type of biopsy | Indications |
|---|---|
|
References
- ↑ 1.0 1.1 Khuntia, Deepak (2015). "Contemporary Review of the Management of Brain Metastasis with Radiation". Advances in Neuroscience. 2015: 1–13. doi:10.1155/2015/372856. ISSN 2356-6787.
- ↑ 2.0 2.1 Microscopic features of brain metastasis. Libre pathology 2015. http://librepathology.org/wiki/index.php/Brain_metastasis. Accessed on November 10, 2015
- ↑ 3.0 3.1 Microscopic appearance of brain metastases. Dr Bruno Di Muzio and Dr Trent Orton et al. Radiopaedia 2015. http://radiopaedia.org/articles/brain-metastases. Accessed on November 10, 2015
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.