Sandbox: DDx Kidney mass: Difference between revisions

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60-70 male patients
von Hippel-Lindau syndrome


* Fever, chills, night sweats, and abdominal pain
* Hematuria, pallor, and weight loss


Polygonal cells, clear cytoplasm, and a central nucleus
 
Delicate branching vasculature
* Costovertebral tenderness
"Chicken wire-like" vasculature
 
Hyaline bodies common
 
* Elevated WBC count
* Elevated ESR and CRP
 
* Well defined hypoechoic area within the corticomedullary parenchyma on U/S
* Well defined mass of low attenuation with a thick, irregular wall or pseudocapsule on CT
 
* Not applicable
 
Angiosarcoma




Chromosome 3 mutation
VHL gene mutation
Gain of chromosome 5


==Nonmalignant causes==
==Nonmalignant causes==
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying

Latest revision as of 20:52, 9 November 2015

  • Fever, chills, night sweats, and abdominal pain
  • Hematuria, pallor, and weight loss


  • Costovertebral tenderness


  • Elevated WBC count
  • Elevated ESR and CRP
  • Well defined hypoechoic area within the corticomedullary parenchyma on U/S
  • Well defined mass of low attenuation with a thick, irregular wall or pseudocapsule on CT
  • Not applicable

Angiosarcoma


Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying