Essential thrombocytosis epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
The incidence of essential thrombocytosis is approximately 0.6-2.5 cases per 100,000 individuals worldwide annually.<ref name="pmid19636672">{{cite journal| author=Fabris F, Randi ML| title=Essential thrombocythemia: past and present. | journal=Intern Emerg Med | year= 2009 | volume= 4 | issue= 5 | pages= 381-8 | pmid=19636672 | doi=10.1007/s11739-009-0284-x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19636672 }} </ref> The prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.<ref name=fm>Essential Thrombocythemia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed on October 29, 2015</ref> The incidence of essential thrombocytosis increases with age; the median age at diagnosis is 65-70 years. Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.<ref>Essential Thrombocythemia (ET). MPN Research foundation. http://www.mpnresearchfoundation.org/Essential-Thrombocythemia Accessed on November 15, 2015.</ref> Females are more commonly affected with essential thrombocytosis than males.<ref>Essential Thrombocythemia (ET). MPN Research foundation. http://www.mpnresearchfoundation.org/Essential-Thrombocythemia Accessed on November 15, 2015.</ref> The female to male ratio is approximately 2 to 1.<ref name="pmid19636672">{{cite journal| author=Fabris F, Randi ML| title=Essential thrombocythemia: past and present. | journal=Intern Emerg Med | year= 2009 | volume= 4 | issue= 5 | pages= 381-8 | pmid=19636672 | doi=10.1007/s11739-009-0284-x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19636672 }} </ref> | The incidence of essential thrombocytosis is approximately 0.6-2.5 cases per 100,000 individuals worldwide annually.<ref name="pmid19636672">{{cite journal| author=Fabris F, Randi ML| title=Essential thrombocythemia: past and present. | journal=Intern Emerg Med | year= 2009 | volume= 4 | issue= 5 | pages= 381-8 | pmid=19636672 | doi=10.1007/s11739-009-0284-x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19636672 }} </ref> The prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.<ref name=fm>Essential Thrombocythemia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed on October 29, 2015</ref> The incidence of essential thrombocytosis increases with age; the median age at diagnosis is 65-70 years. Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.<ref name=gb>Essential Thrombocythemia (ET). MPN Research foundation. http://www.mpnresearchfoundation.org/Essential-Thrombocythemia Accessed on November 15, 2015.</ref> Females are more commonly affected with essential thrombocytosis than males.<ref name=gb>Essential Thrombocythemia (ET). MPN Research foundation. http://www.mpnresearchfoundation.org/Essential-Thrombocythemia Accessed on November 15, 2015.</ref> The female to male ratio is approximately 2 to 1.<ref name="pmid19636672">{{cite journal| author=Fabris F, Randi ML| title=Essential thrombocythemia: past and present. | journal=Intern Emerg Med | year= 2009 | volume= 4 | issue= 5 | pages= 381-8 | pmid=19636672 | doi=10.1007/s11739-009-0284-x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19636672 }} </ref> | ||
==Epidemiology== | ==Epidemiology== | ||
===Incidence=== | ===Incidence=== | ||
*The annual incidence of essential thrombocytosis | *The annual incidence of essential thrombocytosis is estimated to be 0.6-2.5 cases per 100,000 individuals worldwide.<ref name="pmid19636672">{{cite journal| author=Fabris F, Randi ML| title=Essential thrombocythemia: past and present. | journal=Intern Emerg Med | year= 2009 | volume= 4 | issue= 5 | pages= 381-8 | pmid=19636672 | doi=10.1007/s11739-009-0284-x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19636672 }} </ref> | ||
*In reality, the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care. | *In reality, the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care. | ||
===Prevalence=== | ===Prevalence=== | ||
*Worldwide, the prevalence of essential thrombocytosis is | *Worldwide, the prevalence of essential thrombocytosis is approximately 30 for every 100,000 individuals worldwide.<ref name=fm>Essential Thrombocythemia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed on October 29, 2015</ref>. | ||
===Age=== | ===Age=== | ||
*Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.<ref>Essential Thrombocythemia (ET). MPN Research foundation. http://www.mpnresearchfoundation.org/Essential-Thrombocythemia Accessed on November 15, 2015.</ref> | *Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.<ref name=gb>Essential Thrombocythemia (ET). MPN Research foundation. http://www.mpnresearchfoundation.org/Essential-Thrombocythemia Accessed on November 15, 2015.</ref> | ||
*The median age at onset is 65-70 years. | *The median age at onset is 65-70 years. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
The incidence of essential thrombocytosis is approximately 0.6-2.5 cases per 100,000 individuals worldwide annually.[1] The prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.[2] The incidence of essential thrombocytosis increases with age; the median age at diagnosis is 65-70 years. Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.[3] Females are more commonly affected with essential thrombocytosis than males.[3] The female to male ratio is approximately 2 to 1.[1]
Epidemiology
Incidence
- The annual incidence of essential thrombocytosis is estimated to be 0.6-2.5 cases per 100,000 individuals worldwide.[1]
- In reality, the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care.
Prevalence
- Worldwide, the prevalence of essential thrombocytosis is approximately 30 for every 100,000 individuals worldwide.[2].
Age
- Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.[3]
- The median age at onset is 65-70 years.
Gender
- Women in their third decade of life are more commonly affected with essential thrombocytosis than men at same age. The female to male ratio is approximately 2:1.[4]
- Patients who present in the 6th decade of life usually have same incidence in both men and women.
References
- ↑ 1.0 1.1 1.2 Fabris F, Randi ML (2009). "Essential thrombocythemia: past and present". Intern Emerg Med. 4 (5): 381–8. doi:10.1007/s11739-009-0284-x. PMID 19636672.
- ↑ 2.0 2.1 Essential Thrombocythemia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed on October 29, 2015
- ↑ 3.0 3.1 3.2 Essential Thrombocythemia (ET). MPN Research foundation. http://www.mpnresearchfoundation.org/Essential-Thrombocythemia Accessed on November 15, 2015.
- ↑ Brière JB (2007). "Essential thrombocythemia". Orphanet J Rare Dis. 2: 3. doi:10.1186/1750-1172-2-3. PMC 1781427. PMID 17210076.