Sandbox: Bone DDx: Difference between revisions

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* 10-20 yo patients
* 55-60 yo males
* Gradual onset of bone pain
* Back pain
* Pathological fracture
* Palpable vertebral mass


* Limb swelling, tenderness, and warmth
* Palpable lump
* Restricted range of motion


* Bony trabeculae or osteoid tissue
* Discrete, solitary mass male 55 years
* Osteoclast giant cells
* Pain at the site of the skeletal lesion
* Benign spindle cells
* Bone destruction
* Blood-filled spaces of variable sizes


* Sharply defined, expansile osteolytic lesion on CT
* Well-defined, “punched-out” lytic lesions
* Thin sclerotic margins
* Marked erosion, expansion, and destruction of bone cortex
* Air-fluid levels
* Thick ridging around the periphery
* Doughnut sign on bone scan
* “Soap bubble” appearance

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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