Medullary thyroid cancer epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
The incidence of medullary thyroid cancer is approximately 1000 per 100,000 individuals in United States per year. The incidence of medullary thyroid cancer increases with age; the median age at diagnosis peaks in the third to fourth decade.
The [[incidence]] of medullary thyroid cancer is approximately 14.3 per 100,000 individuals worldwide. The [[incidence]] of medullary thyroid cancer increases with age; Sporadic form of medullary thyroid cancer commonly presents in the fifth and sixth decade of life. The [[familial]] form tends to appear earlier in life.  
==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
===Incidence===
* The incidence of medullary thyroid cancer is approximately 1000 per 100,000 individuals in United States per year.
* The overall [[incidence]] of [[thyroid cancer]] is approximately 14.3 per 100,000 individuals worldwide.<ref name="DaviesWelch2006">{{cite journal|last1=Davies|first1=Louise|last2=Welch|first2=H. Gilbert|title=Increasing Incidence of Thyroid Cancer in the United States, 1973-2002|journal=JAMA|volume=295|issue=18|year=2006|pages=2164|issn=0098-7484|doi=10.1001/jama.295.18.2164}}</ref><ref name="DaviesWelch2014">{{cite journal|last1=Davies|first1=Louise|last2=Welch|first2=H. Gilbert|title=Current Thyroid Cancer Trends in the United States|journal=JAMA Otolaryngology–Head & Neck Surgery|volume=140|issue=4|year=2014|pages=317|issn=2168-6181|doi=10.1001/jamaoto.2014.1}}</ref>
===Age===
===Age===
* In nonfamilial cases it typically peaks in the third to fourth decade.<ref name=Radiopaedia2015>{{cite web | title = Medullary thyroid cancer [Dr Matt A. Morgan and Dr Yuranga Weerakkody].Radiopedia 2015| url = http://radiopaedia.org/articles/medullary-thyroid-cancer Accessed on November, 11 2015 }}</ref>
* The [[incidence]] of medullary thyroid cancer increases with [[age]].<ref name="Aschebrook-KilfoyWard2011">{{cite journal|last1=Aschebrook-Kilfoy|first1=Briseis|last2=Ward|first2=Mary H.|last3=Sabra|first3=Mona M.|last4=Devesa|first4=Susan S.|title=Thyroid Cancer Incidence Patterns in the United States by Histologic Type, 1992–2006|journal=Thyroid|volume=21|issue=2|year=2011|pages=125–134|issn=1050-7256|doi=10.1089/thy.2010.0021}}</ref>
* Sporadic form of medullary thyroid cancer commonly presents in the fifth and sixth decade of life.<ref name="WellsAsa2015">{{cite journal|last1=Wells|first1=Samuel A.|last2=Asa|first2=Sylvia L.|last3=Dralle|first3=Henning|last4=Elisei|first4=Rossella|last5=Evans|first5=Douglas B.|last6=Gagel|first6=Robert F.|last7=Lee|first7=Nancy|last8=Machens|first8=Andreas|last9=Moley|first9=Jeffrey F.|last10=Pacini|first10=Furio|last11=Raue|first11=Friedhelm|last12=Frank-Raue|first12=Karin|last13=Robinson|first13=Bruce|last14=Rosenthal|first14=M. Sara|last15=Santoro|first15=Massimo|last16=Schlumberger|first16=Martin|last17=Shah|first17=Manisha|last18=Waguespack|first18=Steven G.|title=Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma|journal=Thyroid|volume=25|issue=6|year=2015|pages=567–610|issn=1050-7256|doi=10.1089/thy.2014.0335}}</ref>
* The [[familial]] form tends to appear earlier in life.
===Gender===
===Gender===
* Medullary thyroid cancer affects men and women equally.
* Medullary thyroid cancer affects women more frequently than men. However, this [[gender]] disparity tends to decrease by advancing the age of individuals.<ref name="Aschebrook-KilfoyWard2011">{{cite journal|last1=Aschebrook-Kilfoy|first1=Briseis|last2=Ward|first2=Mary H.|last3=Sabra|first3=Mona M.|last4=Devesa|first4=Susan S.|title=Thyroid Cancer Incidence Patterns in the United States by Histologic Type, 1992–2006|journal=Thyroid|volume=21|issue=2|year=2011|pages=125–134|issn=1050-7256|doi=10.1089/thy.2010.0021}}</ref>
 
===Race===
* Medullaty thyroid cancer is more common among white and hispanic ethnicities than Asian/Pacific Islanders and blacks.<ref name="Aschebrook-KilfoyWard2011">{{cite journal|last1=Aschebrook-Kilfoy|first1=Briseis|last2=Ward|first2=Mary H.|last3=Sabra|first3=Mona M.|last4=Devesa|first4=Susan S.|title=Thyroid Cancer Incidence Patterns in the United States by Histologic Type, 1992–2006|journal=Thyroid|volume=21|issue=2|year=2011|pages=125–134|issn=1050-7256|doi=10.1089/thy.2010.0021}}</ref><ref name="LairmoreDiesen2015">{{cite journal|last1=Lairmore|first1=Terry C.|last2=Diesen|first2=Diana|last3=Goldfarb|first3=Melanie|last4=Milas|first4=Mira|last5=Ying|first5=Anita K.|last6=Sharma|first6=Jyotirmay|last7=McIver|first7=Bryan|last8=Wong|first8=Richard J.|last9=Randolph|first9=Greg|title=AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: TIMING OF MULTIPLE ENDOCRINE NEOPLASIA THYROIDECTOMY AND EXTENT OF CENTRAL NECK LYMPHADENECTOMY|journal=Endocrine Practice|volume=21|issue=7|year=2015|pages=839–847|issn=1530-891X|doi=10.4158/EP14463.DSCR}}</ref>
===Case fatality/Mortality rate===
* The overall [[mortality rate]] of thyroid cancer is 0.5 per 100,000 worldwide.<ref name="DaviesWelch2014">{{cite journal|last1=Davies|first1=Louise|last2=Welch|first2=H. Gilbert|title=Current Thyroid Cancer Trends in the United States|journal=JAMA Otolaryngology–Head & Neck Surgery|volume=140|issue=4|year=2014|pages=317|issn=2168-6181|doi=10.1001/jamaoto.2014.1}}</ref>
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Latest revision as of 15:14, 29 August 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

The incidence of medullary thyroid cancer is approximately 14.3 per 100,000 individuals worldwide. The incidence of medullary thyroid cancer increases with age; Sporadic form of medullary thyroid cancer commonly presents in the fifth and sixth decade of life. The familial form tends to appear earlier in life.

Epidemiology and Demographics

Incidence

Age

  • The incidence of medullary thyroid cancer increases with age.[3]
  • Sporadic form of medullary thyroid cancer commonly presents in the fifth and sixth decade of life.[4]
  • The familial form tends to appear earlier in life.

Gender

  • Medullary thyroid cancer affects women more frequently than men. However, this gender disparity tends to decrease by advancing the age of individuals.[3]

Race

  • Medullaty thyroid cancer is more common among white and hispanic ethnicities than Asian/Pacific Islanders and blacks.[3][5]

Case fatality/Mortality rate

References

  1. ↑ Davies, Louise; Welch, H. Gilbert (2006). "Increasing Incidence of Thyroid Cancer in the United States, 1973-2002". JAMA. 295 (18): 2164. doi:10.1001/jama.295.18.2164. ISSN 0098-7484.
  2. ↑ 2.0 2.1 Davies, Louise; Welch, H. Gilbert (2014). "Current Thyroid Cancer Trends in the United States". JAMA Otolaryngology–Head & Neck Surgery. 140 (4): 317. doi:10.1001/jamaoto.2014.1. ISSN 2168-6181.
  3. ↑ 3.0 3.1 3.2 Aschebrook-Kilfoy, Briseis; Ward, Mary H.; Sabra, Mona M.; Devesa, Susan S. (2011). "Thyroid Cancer Incidence Patterns in the United States by Histologic Type, 1992–2006". Thyroid. 21 (2): 125–134. doi:10.1089/thy.2010.0021. ISSN 1050-7256.
  4. ↑ Wells, Samuel A.; Asa, Sylvia L.; Dralle, Henning; Elisei, Rossella; Evans, Douglas B.; Gagel, Robert F.; Lee, Nancy; Machens, Andreas; Moley, Jeffrey F.; Pacini, Furio; Raue, Friedhelm; Frank-Raue, Karin; Robinson, Bruce; Rosenthal, M. Sara; Santoro, Massimo; Schlumberger, Martin; Shah, Manisha; Waguespack, Steven G. (2015). "Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma". Thyroid. 25 (6): 567–610. doi:10.1089/thy.2014.0335. ISSN 1050-7256.
  5. ↑ Lairmore, Terry C.; Diesen, Diana; Goldfarb, Melanie; Milas, Mira; Ying, Anita K.; Sharma, Jyotirmay; McIver, Bryan; Wong, Richard J.; Randolph, Greg (2015). "AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: TIMING OF MULTIPLE ENDOCRINE NEOPLASIA THYROIDECTOMY AND EXTENT OF CENTRAL NECK LYMPHADENECTOMY". Endocrine Practice. 21 (7): 839–847. doi:10.4158/EP14463.DSCR. ISSN 1530-891X.


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