Linitis plastica laboratory tests: Difference between revisions
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{{Linitis plastica}} | {{Linitis plastica}} | ||
{{CMG}}{{AE}} {{ | {{CMG}}; {{AE}}{{HM}} | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of linitis plastica may include abnormal complete blood picture, electrolyte abnormalities, occult | There are no diagnostic laboratory findings for linitis plastica. Laboratory findings consistent with the diagnosis of linitis plastica may include abnormal complete blood picture, [[electrolyte]] abnormalities, and [[occult blood]]. Linitis plastica often metastasizes to the liver in the advanced stages, this is associated with an elevated alkaline phosphatase. | ||
==Laboratory findings== | ==Laboratory Findings== | ||
Laboratory testing may be similar to that of any other type of gastric cancer and may include the following: | *There are no diagnostic laboratory findings associated with linitis plastica.<ref name="pmid8239772">{{cite journal |vauthors=Wanebo HJ, Kennedy BJ, Chmiel J, Steele G, Winchester D, Osteen R |title=Cancer of the stomach. A patient care study by the American College of Surgeons |journal=Ann. Surg. |volume=218 |issue=5 |pages=583–92 |year=1993 |pmid=8239772 |pmc=1243028 |doi= |url=}}</ref><ref name="pmid7776992">{{cite journal |vauthors=Fuchs CS, Mayer RJ |title=Gastric carcinoma |journal=N. Engl. J. Med. |volume=333 |issue=1 |pages=32–41 |year=1995 |pmid=7776992 |doi=10.1056/NEJM199507063330107 |url=}}</ref><ref name="pmid8640661">{{cite journal |vauthors=Horie Y, Miura K, Matsui K, Yukimasa A, Ohi S, Hamamoto T, Kawasaki H |title=Marked elevation of plasma carcinoembryonic antigen and stomach carcinoma |journal=Cancer |volume=77 |issue=10 |pages=1991–7 |year=1996 |pmid=8640661 |doi=10.1002/(SICI)1097-0142(19960515)77:10<1991::AID-CNCR5>3.0.CO;2-K |url=}}</ref> | ||
*Complete blood count (CBC) | *Laboratory testing may be similar to that of any other type of gastric cancer and may include the following: | ||
**To look for anemia | **[[Complete blood count]] ([[CBC]]) | ||
*Complete metabolic panel (CMP) | ***To look for [[anemia]] | ||
**To look for any electrolyte abnormalities | **Complete metabolic panel (CMP) | ||
*Stool testing for occult blood | ***To look for any electrolyte abnormalities | ||
*Serum chemistry tests | **Stool testing for [[occult blood]] | ||
**Increase in | **Serum chemistry tests | ||
*Tumor | ***Increase in [[alanine aminotransferase]] (ALT), [[lactate dehydrogenase]] (LDH), alkaline phosphatase and [[aspartate transaminase]] (AST) levels may be noticed | ||
**[[Tumor marker]] testing may be positive for [[CA-125]], [[CEA]], CA 19-9. CA72-4, AFP and beta [[hCG]] | |||
==References== | ==References== | ||
Latest revision as of 19:59, 16 January 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
There are no diagnostic laboratory findings for linitis plastica. Laboratory findings consistent with the diagnosis of linitis plastica may include abnormal complete blood picture, electrolyte abnormalities, and occult blood. Linitis plastica often metastasizes to the liver in the advanced stages, this is associated with an elevated alkaline phosphatase.
Laboratory Findings
- There are no diagnostic laboratory findings associated with linitis plastica.[1][2][3]
- Laboratory testing may be similar to that of any other type of gastric cancer and may include the following:
- Complete blood count (CBC)
- To look for anemia
- Complete metabolic panel (CMP)
- To look for any electrolyte abnormalities
- Stool testing for occult blood
- Serum chemistry tests
- Increase in alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alkaline phosphatase and aspartate transaminase (AST) levels may be noticed
- Tumor marker testing may be positive for CA-125, CEA, CA 19-9. CA72-4, AFP and beta hCG
- Complete blood count (CBC)
References
- ↑ Wanebo HJ, Kennedy BJ, Chmiel J, Steele G, Winchester D, Osteen R (1993). "Cancer of the stomach. A patient care study by the American College of Surgeons". Ann. Surg. 218 (5): 583–92. PMC 1243028. PMID 8239772.
- ↑ Fuchs CS, Mayer RJ (1995). "Gastric carcinoma". N. Engl. J. Med. 333 (1): 32–41. doi:10.1056/NEJM199507063330107. PMID 7776992.
- ↑ Horie Y, Miura K, Matsui K, Yukimasa A, Ohi S, Hamamoto T, Kawasaki H (1996). "Marked elevation of plasma carcinoembryonic antigen and stomach carcinoma". Cancer. 77 (10): 1991–7. doi:10.1002/(SICI)1097-0142(19960515)77:10<1991::AID-CNCR5>3.0.CO;2-K. PMID 8640661.