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<SMALL>Data from the Center of Disease Control and Prevention, as of May 2015</SMALL>
<SMALL>Data from the Center of Disease Control and Prevention, as of May 2015</SMALL>
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[[Image:Lassa fever history.jpg|600 px|<sup>A physician examining a patient with Lassa fever patient in West Africa in 1977.<br>Image retrieved from the Centers for Disease Control and Prevention (CDC) - Lassa Fever History</sup><ref name="CDC PHIL Lassa History">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention- Lassa fever history | url = http://phil.cdc.gov/phil/details.asp}}</ref>]]
[[Image:Lassa fever history.jpg|600 px]]<br>
<sup>A physician examining a patient with Lassa fever patient in West Africa in 1977. Image retrieved from the Centers for Disease Control and Prevention (CDC) - Lassa Fever History</sup><ref name="CDC PHIL Lassa History">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention- Lassa fever history | url = http://phil.cdc.gov/phil/details.asp}}</ref>


==References==
==References==
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[[Category:Tropical disease]]
[[Category:Tropical disease]]
[[Category:Biological weapons]]
[[Category:Biological weapons]]
[[Category:Infectious disease]]

Latest revision as of 18:08, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

The first case of documented Lassa fever was reported in 1969 following the death of 2 nurses in Lassa, Nigeria.

Historical Perspective

  • In 1955-1956, epidemics with clinical and epidemiological resemblance to Lassa fever were reported in Eastern Province and Sierra Leone.
  • The first case of documented Lassa fever was reported in 1969 following the death of 2 nurses in Lassa, Nigeria.[1] Prior to that, similar cases in West Africa were reported and thought to be caused by Lassa fever given the clinical and epidemiological resemblance of the presentation to Lassa fever.
  • Administration of ribavirin for the treatment of Lassa fever was first introduced by Joe McCormick in 1979.
  • Lassa fever is uncommon outside West Africa. Only 6 patients with Lassa fever have historically been hospitalized in USA (all 6 patients had recently traveled to West Africa). The most recent case of Lassa fever in USA was reported in May 2015.
Year of import Clinical features From To
1969 Fever, malaise, headache, nausea, sore throat, epigastric/right upper quadrant tenderness, pleural effusion, facial/cervical edema, dysphagia, elevated transaminases, cough, dyspnea, pulmonary infiltrates, epiglottal edema, lethargy, nystagmus, lightheadedness, dizziness without vertigo, ataxia, alopecia Nigeria New York
1975 Abdominal pain, diarrhea, fever, headache, myalgia, arthralgia, conjunctival injection, lymphadenopathy, weight loss, pleuritic chest pain, pleural effusion, unilateral deafness Sierra Leone Washington, DC
1976 Abdominal cramps, nausea, vomiting, diarrhea, fatigue, headache, retroorbital pain, neck/back pain, paresthesias, right ear pain, fever, vertigo, syncope, dysmorphopsias, alopecia, weight loss, ecchymoses, insomnia, depression, hypotension, left-sided facial weakness, right-sided Babinski reflex, Weber test lateralized to the left Sierra Leone Washington, DC
1989 Shaking chills, fever, sore throat, myalgia, headache, dysphagia, bloody diarrhea, elevated transaminases, hypotension, adult respiratory distress syndrome, death Nigeria Chicago, IL
2004 Chills, fever, sore throat, diarrhea, back pain, adult respiratory distress syndrome, death Sierra Leone and Liberia Trenton, New Jersy
2015 Fever, sore throat, tiredness, death Liberia New Jersy

Data from the Center of Disease Control and Prevention, as of May 2015

A physician examining a patient with Lassa fever patient in West Africa in 1977. Image retrieved from the Centers for Disease Control and Prevention (CDC) - Lassa Fever History[2]

References

  1. Monath TP (1975). "Lassa fever: review of epidemiology and epizootiology". Bull World Health Organ. 52 (4–6): 577–92. PMC 2366662. PMID 782738.
  2. "Public Health Image Library (PHIL), Centers for Disease Control and Prevention- Lassa fever history".