Adult T-cell leukemia physical examination: Difference between revisions

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{{Adult T-cell leukemia}}
{{Adult T-cell leukemia}}
{{CMG}} {{AE}} {{HL}}  
{{CMG}}; {{AE}} {{HL}}; {{GRR}} {{Nat}}
==Overview==
==Overview==
Patients with adult T-cell leukemia usually appear lethargic and fatigued. Physical examination of patients with adult T-cell leukemia is usually remarkable for [[maculopapular]] [[rash]], skin [[ulceration]], and [[splenomegaly]].
==Physical Examination==
==Physical Examination==
The following physical findings may be observed in patients suffering from adult T-cell leukemia:<ref name="pmid18042693">{{cite journal| author=Matutes E| title=Adult T-cell leukaemia/lymphoma. | journal=J Clin Pathol | year= 2007 | volume= 60 | issue= 12 | pages= 1373-7 | pmid=18042693 | doi=10.1136/jcp.2007.052456 | pmc=PMC2095573 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18042693  }} </ref><ref name="pmid19030219">{{cite journal |vauthors=Hokama A, Tomoyose T, Yamamoto Y, Watanabe T, Hirata T, Kinjo F, Kato S, Ohshima K, Uezato H, Takasu N, Fujita J |title=Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis |journal=World J. Gastroenterol. |volume=14 |issue=42 |pages=6584–8 |date=November 2008 |pmid=19030219 |pmc=2773353 |doi= |url=}}</ref><ref name="TaniguchiTakenaka1988">{{cite journal|last1=Taniguchi|first1=Atsuo|last2=Takenaka|first2=Yoshitaka|last3=Noda|first3=Yumiko|last4=Ueno|first4=Yukio|last5=Shichikawa|first5=Kanji|last6=Sato|first6=Kazuto|last7=Miyasaka|first7=Nobuyuki|last8=Nishioka|first8=Kusuki|title=Adult t cell leukemia presenting with prolifeerative synovitis|journal=Arthritis & Rheumatism|volume=31|issue=8|year=1988|pages=1076–1077|issn=00043591|doi=10.1002/art.1780310824}}</ref><ref name="HermineBouscary1995">{{cite journal|last1=Hermine|first1=Olivier|last2=Bouscary|first2=Didier|last3=Gessain|first3=Antoine|last4=Turlure|first4=Pascal|last5=Leblond|first5=Veronique|last6=Franck|first6=Nathalie|last7=Buzyn-Veil|first7=Agnes|last8=Rio|first8=Bernard|last9=Macintyre|first9=Elisabeth|last10=Dreyfus|first10=Francois|last11=Bazarbachi|first11=Ali|title=Treatment of Adult T-Cell Leukemia-Lymphoma with Zidovudine and Interferon Alfa|journal=New England Journal of Medicine|volume=332|issue=26|year=1995|pages=1749–1751|issn=0028-4793|doi=10.1056/NEJM199506293322604}}</ref>
===General Appearance===
===General Appearance===
* Adult T-cell leukemia patients often appear lethargic and fatigued
* Adult T-cell leukemia patients often appear [[lethargic]] and [[fatigue|fatigued]].
===Vital Signs===
===Vital Signs===
* Low grade [[fever]]
* Low grade [[fever]]
===Skin===
===Skin===
* [[Maculopapular]] [[rash]]
* [[Maculopapular]] [[rash]]
* Skin [[ulceration]]
* [[Skin]] [[ulceration]]
* Leukemia cutis - leukemic infiltration of skin
* Leukemia cutis (infiltration of skin by leukemic cells)
 
===HEENT===
===HEENT===
* HEENT examination of patients with adult T-cell leukemia is usually normal.
=== Neck ===
* [[Lymphadenopathy]]
* [[Lymphadenopathy]]
===Abdomen===
===Lungs===
* Pulmonary examination of patients with adult T-cell leukemia is usually normal.
 
=== Heart ===
* [[Tachycardia]]
* Abnormal [[heart rhythm]] may be present
 
=== Abdomen ===
* [[Splenomegaly]]
* [[Splenomegaly]]
* [[Hepatomegaly]]  
* [[Hepatomegaly]]  
===Cardiac Exam===
===Back===
* Tachycardia 
* Back examination of patients with adult T-cell leukemia is usually normal.
* Abnormal heart rhythm may be present
 
===Skeletal===
=== Genitourinary ===
* Muscle wasting
* Genitourinary examination of patients with adult T-cell leukemia is usually normal.
 
=== Neuromuscular ===
* [[Muscle]] wasting
 
=== Extremities ===
* [[Muscle]] wasting
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WS}}


[[Category:Disease]]
[[Category:Medicine]]
[[Category:Pathology]]
[[Category:Hematology]]
[[Category:Hematology]]
[[Category:Immunology]]
[[Category:Infectious disease]]
[[Category:Oncology]]
[[Category:Up-To-Date]]

Latest revision as of 20:19, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]; Grammar Reviewer: Natalie Harpenau, B.S.[3]

Overview

Patients with adult T-cell leukemia usually appear lethargic and fatigued. Physical examination of patients with adult T-cell leukemia is usually remarkable for maculopapular rash, skin ulceration, and splenomegaly.

Physical Examination

The following physical findings may be observed in patients suffering from adult T-cell leukemia:[1][2][3][4]

General Appearance

Vital Signs

Skin

HEENT

  • HEENT examination of patients with adult T-cell leukemia is usually normal.

Neck

Lungs

  • Pulmonary examination of patients with adult T-cell leukemia is usually normal.

Heart

Abdomen

Back

  • Back examination of patients with adult T-cell leukemia is usually normal.

Genitourinary

  • Genitourinary examination of patients with adult T-cell leukemia is usually normal.

Neuromuscular

Extremities

References

  1. ↑ Matutes E (2007). "Adult T-cell leukaemia/lymphoma". J Clin Pathol. 60 (12): 1373–7. doi:10.1136/jcp.2007.052456. PMC 2095573. PMID 18042693.
  2. ↑ Hokama A, Tomoyose T, Yamamoto Y, Watanabe T, Hirata T, Kinjo F, Kato S, Ohshima K, Uezato H, Takasu N, Fujita J (November 2008). "Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis". World J. Gastroenterol. 14 (42): 6584–8. PMC 2773353. PMID 19030219.
  3. ↑ Taniguchi, Atsuo; Takenaka, Yoshitaka; Noda, Yumiko; Ueno, Yukio; Shichikawa, Kanji; Sato, Kazuto; Miyasaka, Nobuyuki; Nishioka, Kusuki (1988). "Adult t cell leukemia presenting with prolifeerative synovitis". Arthritis & Rheumatism. 31 (8): 1076–1077. doi:10.1002/art.1780310824. ISSN 0004-3591.
  4. ↑ Hermine, Olivier; Bouscary, Didier; Gessain, Antoine; Turlure, Pascal; Leblond, Veronique; Franck, Nathalie; Buzyn-Veil, Agnes; Rio, Bernard; Macintyre, Elisabeth; Dreyfus, Francois; Bazarbachi, Ali (1995). "Treatment of Adult T-Cell Leukemia-Lymphoma with Zidovudine and Interferon Alfa". New England Journal of Medicine. 332 (26): 1749–1751. doi:10.1056/NEJM199506293322604. ISSN 0028-4793.
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