Osteochondroma classification: Difference between revisions
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==Overview== | ==Overview== | ||
Osteochondromas may be classified into 2 subtypes: solitary osteochondromas (non-hereditary) and multiple osteochondromas (hereditary).<ref name="pmid18853760">{{cite journal |vauthors=Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M |title=Osteochondromas: review of the clinical, radiological and pathological features |journal=In Vivo (Athens, Greece) |volume=22 |issue=5 |pages=633–46 |year=2008 |pmid=18853760 |doi= |url=http://iv.iiarjournals.org/cgi/pmidlookup?view=long&pmid=18853760}}</ref> | |||
==Classification== | |||
== | The table below differentiates between the 2 subtypes of osteochondromas:<ref name="pmid18853760">{{cite journal |vauthors=Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M |title=Osteochondromas: review of the clinical, radiological and pathological features |journal=In Vivo (Athens, Greece) |volume=22 |issue=5 |pages=633–46 |year=2008 |pmid=18853760 |doi= |url=http://iv.iiarjournals.org/cgi/pmidlookup?view=long&pmid=18853760}}</ref><ref name="pmid25728463">{{cite journal |vauthors=Kushner BH, Roberts SS, Friedman DN, Kuk D, Ostrovnaya I, Modak S, Kramer K, Basu EM, Cheung NK |title=Osteochondroma in long-term survivors of high-risk neuroblastoma |journal=Cancer |volume=121 |issue=12 |pages=2090–6 |date=June 2015 |pmid=25728463 |pmc=4970322 |doi=10.1002/cncr.29316 |url=}}</ref><ref name="pmid17211603">{{cite journal |vauthors=Marcovici PA, Berdon WE, Liebling MS |title=Osteochondromas and growth retardation secondary to externally or internally administered radiation in childhood |journal=Pediatr Radiol |volume=37 |issue=3 |pages=301–4 |date=March 2007 |pmid=17211603 |doi=10.1007/s00247-006-0382-0 |url=}}</ref><ref name="pmid19747635">{{cite journal |vauthors=Faraci M, Bagnasco F, Corti P, Messina C, Fagioli F, Podda M, Prete A, Caselli D, Lanino E, Dini G, Rondelli R, Haupt R |title=Osteochondroma after hematopoietic stem cell transplantation in childhood. An Italian study on behalf of the AIEOP-HSCT group |journal=Biol. Blood Marrow Transplant. |volume=15 |issue=10 |pages=1271–6 |date=October 2009 |pmid=19747635 |doi=10.1016/j.bbmt.2009.06.003 |url=}}</ref><ref name="pmid18328980">{{cite journal |vauthors=Pannier S, Legeai-Mallet L |title=Hereditary multiple exostoses and enchondromatosis |journal=Best Pract Res Clin Rheumatol |volume=22 |issue=1 |pages=45–54 |date=March 2008 |pmid=18328980 |doi=10.1016/j.berh.2007.12.004 |url=}}</ref><ref name="pmid18271966">{{cite journal |vauthors=Bovée JV |title=Multiple osteochondromas |journal=Orphanet J Rare Dis |volume=3 |issue= |pages=3 |date=February 2008 |pmid=18271966 |pmc=2276198 |doi=10.1186/1750-1172-3-3 |url=}}</ref><ref name="pmid8027127">{{cite journal |vauthors=Schmale GA, Conrad EU, Raskind WH |title=The natural history of hereditary multiple exostoses |journal=J Bone Joint Surg Am |volume=76 |issue=7 |pages=986–92 |date=July 1994 |pmid=8027127 |doi=10.2106/00004623-199407000-00005 |url=}}</ref><ref name="pmid7702095">{{cite journal |vauthors=Wicklund CL, Pauli RM, Johnston D, Hecht JT |title=Natural history study of hereditary multiple exostoses |journal=Am. J. Med. Genet. |volume=55 |issue=1 |pages=43–6 |date=January 1995 |pmid=7702095 |doi=10.1002/ajmg.1320550113 |url=}}</ref> | ||
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!style="background: #4479BA; width: 50px;" |{{fontcolor|#FFF|Type of Osteochondroma}} | |||
!style="background: #4479BA; width: 150px;" |{{fontcolor|#FFF|Features}} | |||
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|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;"| Solitary osteochondroma | |||
|style="padding: 5px 5px; background: #F5F5F5;"| | |||
*Non-hereditary | |||
*85% of osteochondromas | |||
*No genetic mutations | |||
*Located in long bones | |||
*Onset is in early adolescence | |||
|- | |||
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;"| Multiple osteochondromas | |||
|style="padding: 5px 5px; background: #F5F5F5;"| | |||
*Hereditary | |||
*Approximately 20% of osteochondromas | |||
*Related genetic mutations EXT-1 and EXT-2 | |||
*Early onset of disease (newborn or children) | |||
|} | |||
==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Orthopedics]] | |||
Latest revision as of 01:56, 14 October 2019
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Osteochondroma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Osteochondroma classification On the Web |
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American Roentgen Ray Society Images of Osteochondroma classification |
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Risk calculators and risk factors for Osteochondroma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Osteochondromas may be classified into 2 subtypes: solitary osteochondromas (non-hereditary) and multiple osteochondromas (hereditary).[1]
Classification
The table below differentiates between the 2 subtypes of osteochondromas:[1][2][3][4][5][6][7][8]
| Type of Osteochondroma | Features |
|---|---|
| Solitary osteochondroma |
|
| Multiple osteochondromas |
|
References
- ↑ 1.0 1.1 Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M (2008). "Osteochondromas: review of the clinical, radiological and pathological features". In Vivo (Athens, Greece). 22 (5): 633–46. PMID 18853760.
- ↑ Kushner BH, Roberts SS, Friedman DN, Kuk D, Ostrovnaya I, Modak S, Kramer K, Basu EM, Cheung NK (June 2015). "Osteochondroma in long-term survivors of high-risk neuroblastoma". Cancer. 121 (12): 2090–6. doi:10.1002/cncr.29316. PMC 4970322. PMID 25728463.
- ↑ Marcovici PA, Berdon WE, Liebling MS (March 2007). "Osteochondromas and growth retardation secondary to externally or internally administered radiation in childhood". Pediatr Radiol. 37 (3): 301–4. doi:10.1007/s00247-006-0382-0. PMID 17211603.
- ↑ Faraci M, Bagnasco F, Corti P, Messina C, Fagioli F, Podda M, Prete A, Caselli D, Lanino E, Dini G, Rondelli R, Haupt R (October 2009). "Osteochondroma after hematopoietic stem cell transplantation in childhood. An Italian study on behalf of the AIEOP-HSCT group". Biol. Blood Marrow Transplant. 15 (10): 1271–6. doi:10.1016/j.bbmt.2009.06.003. PMID 19747635.
- ↑ Pannier S, Legeai-Mallet L (March 2008). "Hereditary multiple exostoses and enchondromatosis". Best Pract Res Clin Rheumatol. 22 (1): 45–54. doi:10.1016/j.berh.2007.12.004. PMID 18328980.
- ↑ Bovée JV (February 2008). "Multiple osteochondromas". Orphanet J Rare Dis. 3: 3. doi:10.1186/1750-1172-3-3. PMC 2276198. PMID 18271966.
- ↑ Schmale GA, Conrad EU, Raskind WH (July 1994). "The natural history of hereditary multiple exostoses". J Bone Joint Surg Am. 76 (7): 986–92. doi:10.2106/00004623-199407000-00005. PMID 8027127.
- ↑ Wicklund CL, Pauli RM, Johnston D, Hecht JT (January 1995). "Natural history study of hereditary multiple exostoses". Am. J. Med. Genet. 55 (1): 43–6. doi:10.1002/ajmg.1320550113. PMID 7702095.