Glomus tumor history and symptoms: Difference between revisions

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==Overview==
==Overview==
A detailed history from the patient may be helpful. A positive history of [[trauma]] may be present.<ref name="pmid20322052">{{cite journal| author=Blanchard AJ| title=The Pathology of Glomus Tumours. | journal=Can Med Assoc J | year= 1941 | volume= 44 | issue= 4 | pages= 357-60 | pmid=20322052 | doi= | pmc=PMC1827043 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20322052  }} </ref> A positive family history may be present in patients with multiple glomus tumors ([[autosomal dominant]]).Symptoms of glomus tumor include [[hypersensitivity]] to cold and paroxysmal pain at a well defined site.<ref name="pmid20038364">{{cite journal| author=Samaniego E, Crespo A, Sanz A| title=[Key diagnostic features and treatment of subungual glomus tumor]. | journal=Actas Dermosifiliogr | year= 2009 | volume= 100 | issue= 10 | pages= 875-82 | pmid=20038364 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20038364  }} </ref>
A detailed history from the patient may be helpful. A positive history of [[trauma]] may be present. A positive family history may be present in patients with multiple glomus tumors ([[autosomal dominant]]).Symptoms of glomus tumor include [[hypersensitivity]] to cold and paroxysmal pain at a well defined site.  


==History==
==History==
*A detailed history from the patient may be helpful. A positive history of trauma may be present.<ref name="pmid20322052">{{cite journal| author=Blanchard AJ| title=The Pathology of Glomus Tumours. | journal=Can Med Assoc J | year= 1941 | volume= 44 | issue= 4 | pages= 357-60 | pmid=20322052 | doi= | pmc=PMC1827043 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20322052  }} </ref>
*A detailed history from the patient may be helpful. A positive history of trauma may be present.<ref name="pmid20322052">{{cite journal| author=Blanchard AJ| title=The Pathology of Glomus Tumours. | journal=Can Med Assoc J | year= 1941 | volume= 44 | issue= 4 | pages= 357-60 | pmid=20322052 | doi= | pmc=PMC1827043 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20322052  }} </ref>
*A positive family history may be present in patients with multiple glomus tumors ([[autosomal dominant]]).
**There is a delay in diagnosis of the lesions (sometimes up to 15 years) that was apparent both in several cases described in the literature.<ref name="pmid15215032">{{cite journal| author=Pater TJ, Marks RM| title=Glomus tumor of the hallux: case presentation and review of the literature. | journal=Foot Ankle Int | year= 2004 | volume= 25 | issue= 6 | pages= 434-7 | pmid=15215032 | doi=10.1177/107110070402500614 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15215032  }}</ref><ref name="pmid12755514">{{cite journal| author=Tomak Y, Akcay I, Dabak N, Eroglu L| title=Subungual glomus tumours of the hand: diagnosis and treatment of 14 cases. | journal=Scand J Plast Reconstr Surg Hand Surg | year= 2003 | volume= 37 | issue= 2 | pages= 121-4 | pmid=12755514 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12755514  }} </ref>
*A positive family history may be present in patients with multiple glomus tumors ([[autosomal dominant]]).<ref name="pmid20322052">{{cite journal| author=Blanchard AJ| title=The Pathology of Glomus Tumours. | journal=Can Med Assoc J | year= 1941 | volume= 44 | issue= 4 | pages= 357-60 | pmid=20322052 | doi= | pmc=PMC1827043 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20322052  }} </ref>


==Symptoms==
==Symptoms==
*Symptoms of solitary glomus tumour include:<ref name=pl>Glomangioma. Radiopedia. http://radiopaedia.org/articles/glomangioma Accessed on January 12, 2016.</ref><ref name=kp>Glomus tumor. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1735996/ Accessed on January 12, 2016.</ref>  
*Symptoms of solitary glomus tumor include:<ref name="pmid15689436">{{cite journal| author=Brouillard P, Ghassibé M, Penington A, Boon LM, Dompmartin A, Temple IK et al.| title=Four common glomulin mutations cause two thirds of glomuvenous malformations ("familial glomangiomas"): evidence for a founder effect. | journal=J Med Genet | year= 2005 | volume= 42 | issue= 2 | pages= e13 | pmid=15689436 | doi=10.1136/jmg.2004.024174 | pmc=1735996 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15689436  }}</ref><ref name="pmid20038364">{{cite journal| author=Samaniego E, Crespo A, Sanz A| title=[Key diagnostic features and treatment of subungual glomus tumor]. | journal=Actas Dermosifiliogr | year= 2009 | volume= 100 | issue= 10 | pages= 875-82 | pmid=20038364 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20038364  }}</ref>  
**Pain
**Pain
***Paroxysmal
***Paroxysmal
***Reproduced when the lesion is placed in cold water
***Cold sensitivity
****Reproduced when the lesion is placed in cold water
***May worsen at night
***May worsen at night
***Extreme point tenderness in the region of the tumor
***Disappears when a [[tourniquet]] is applied
***Disappears when a [[tourniquet]] is applied
***Subungual glomus tumors are particularly painful
**Multiple glomus tumors are usually painless.
**Multiple glomus tumors are usually painless.


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Latest revision as of 01:34, 9 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

A detailed history from the patient may be helpful. A positive history of trauma may be present. A positive family history may be present in patients with multiple glomus tumors (autosomal dominant).Symptoms of glomus tumor include hypersensitivity to cold and paroxysmal pain at a well defined site.

History

  • A detailed history from the patient may be helpful. A positive history of trauma may be present.[1]
    • There is a delay in diagnosis of the lesions (sometimes up to 15 years) that was apparent both in several cases described in the literature.[2][3]
  • A positive family history may be present in patients with multiple glomus tumors (autosomal dominant).[1]

Symptoms

  • Symptoms of solitary glomus tumor include:[4][5]
    • Pain
      • Paroxysmal
      • Cold sensitivity
        • Reproduced when the lesion is placed in cold water
      • May worsen at night
      • Extreme point tenderness in the region of the tumor
      • Disappears when a tourniquet is applied
      • Subungual glomus tumors are particularly painful
    • Multiple glomus tumors are usually painless.

References

  1. 1.0 1.1 Blanchard AJ (1941). "The Pathology of Glomus Tumours". Can Med Assoc J. 44 (4): 357–60. PMC 1827043. PMID 20322052.
  2. Pater TJ, Marks RM (2004). "Glomus tumor of the hallux: case presentation and review of the literature". Foot Ankle Int. 25 (6): 434–7. doi:10.1177/107110070402500614. PMID 15215032.
  3. Tomak Y, Akcay I, Dabak N, Eroglu L (2003). "Subungual glomus tumours of the hand: diagnosis and treatment of 14 cases". Scand J Plast Reconstr Surg Hand Surg. 37 (2): 121–4. PMID 12755514.
  4. Brouillard P, Ghassibé M, Penington A, Boon LM, Dompmartin A, Temple IK; et al. (2005). "Four common glomulin mutations cause two thirds of glomuvenous malformations ("familial glomangiomas"): evidence for a founder effect". J Med Genet. 42 (2): e13. doi:10.1136/jmg.2004.024174. PMC 1735996. PMID 15689436.
  5. Samaniego E, Crespo A, Sanz A (2009). "[Key diagnostic features and treatment of subungual glomus tumor]". Actas Dermosifiliogr. 100 (10): 875–82. PMID 20038364.


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