Mesothelioma epidemiology and demographics: Difference between revisions

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{{Mesothelioma}}
{{Mesothelioma}}
{{CMG}}{{AE}}{{PSD}}, {{SR}}
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==Overview==
==Overview==
Mesothelioma is a rare disease which accounts for 5-28% of all malignancies that involve the pleura. The [[incidence]] of mesothelioma is estimated to be 3,000 cases annually. The [[incidence]] of [[pleural]] mesothelioma is approximately 1 per 100,000 individuals in the United States. Males are more commonly affected with mesothelioma than females. The male to female ratio is approximately 3 to 1. The [[incidence]] of mesothelioma increases with age; the median age at diagnosis for [[pleural]] mesothelioma and [[peritoneal]] mesothelioma are 74 years and 68 years, respectively. There is no racial predilection to mesothelioma.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Prevalence===
===Prevalence===
Mesothelioma is a rare disease which accounts for 5-28% of all malignancies that involve the pleura.<ref name=epidemiologymesothelioma1>Epidemiology of mesothelioma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/mesothelioma. Accessed on February 8, 2016</ref>
*Mesothelioma is a rare disease which accounts for 5-28% of all malignancies that involve the pleura.<ref name="epidemiologymesothelioma1">Epidemiology of mesothelioma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/mesothelioma. Accessed on February 8, 2016</ref>


===Incidence===
===Incidence===
*The incidence of mesothelioma is estimated to be 3,000 cases annually.<ref name="A.X.2012">Philip A. Rascoe, Xiaobo X. Cao and W. Roy Smythe (2012). Molecular Pathogenesis of Malignant Pleural Mesothelioma, Mesotheliomas - Synonyms and Definition, Epidemiology, Etiology, Pathogenesis, Cyto-Histopathological Features, Clinic, Diagnosis, Treatment, Prognosis, Dr Alexander Zubritsky (Ed.), ISBN: 978-953-307-845-8, InTech, Available from: http://www.intechopen.com/books/mesotheliomas-synonyms-and-definition-epidemiology-etiology-pathogenesis-cyto-histopathological-features-clinic-diagnosis-treatment-prognosis/molecular-pathogenesis-of-malignant-pleural-mesothelioma</ref>
*The [[incidence]] of mesothelioma is estimated to be 3,000 cases annually.<ref name="A.X.2012">Philip A. Rascoe, Xiaobo X. Cao and W. Roy Smythe (2012). Molecular Pathogenesis of Malignant Pleural Mesothelioma, Mesotheliomas - Synonyms and Definition, Epidemiology, Etiology, Pathogenesis, Cyto-Histopathological Features, Clinic, Diagnosis, Treatment, Prognosis, Dr Alexander Zubritsky (Ed.), ISBN: 978-953-307-845-8, InTech, Available from: http://www.intechopen.com/books/mesotheliomas-synonyms-and-definition-epidemiology-etiology-pathogenesis-cyto-histopathological-features-clinic-diagnosis-treatment-prognosis/molecular-pathogenesis-of-malignant-pleural-mesothelioma</ref>
*The incidence of mesothelioma has decreased over several decades in the United States coincident with diminishing occupational [[asbestos]] exposure and has remained stable since 2003.<ref name="ThomasChen2015">{{cite journal|last1=Thomas|first1=Anish|last2=Chen|first2=Yuanbin|last3=Yu|first3=Tinghui|last4=Gill|first4=Ammara|last5=Prasad|first5=Vinay|title=Distinctive clinical characteristics of malignant mesothelioma in young patients|journal=Oncotarget|volume=6|issue=18|year=2015|pages=16766–16773|issn=1949-2553|doi=10.18632/oncotarget.4414}}</ref>
*The [[incidence]] of pleural mesothelioma is approximately 1 per 100,000 individuals in the United States.<ref name="Saint-PierrePease2015">{{cite journal|last1=Saint-Pierre|first1=Mathieu D.|last2=Pease|first2=Christopher|last3=Mithoowani|first3=Hamid|last4=Zhang|first4=Tinghua|last5=Nicholas|first5=Garth A.|last6=Laurie|first6=Scott A.|last7=Wheatley-Price|first7=Paul|title=Malignant Pleural Mesothelioma Outcomes in the Era of Combined Platinum and Folate Antimetabolite Chemotherapy|journal=Lung Cancer International|volume=2015|year=2015|pages=1–7|issn=2090-3197|doi=10.1155/2015/590148}}</ref>
*The [[incidence]] of pleural mesothelioma is approximately 1.2 per 100,000 individuals in Canada.<ref name="Saint-PierrePease2015">{{cite journal|last1=Saint-Pierre|first1=Mathieu D.|last2=Pease|first2=Christopher|last3=Mithoowani|first3=Hamid|last4=Zhang|first4=Tinghua|last5=Nicholas|first5=Garth A.|last6=Laurie|first6=Scott A.|last7=Wheatley-Price|first7=Paul|title=Malignant Pleural Mesothelioma Outcomes in the Era of Combined Platinum and Folate Antimetabolite Chemotherapy|journal=Lung Cancer International|volume=2015|year=2015|pages=1–7|issn=2090-3197|doi=10.1155/2015/590148}}</ref>
*The [[incidence]] of mesothelioma has decreased over several decades in the United States coincident with diminishing occupational [[asbestos]] exposure and has remained stable since 2003.<ref name="ThomasChen2015">{{cite journal|last1=Thomas|first1=Anish|last2=Chen|first2=Yuanbin|last3=Yu|first3=Tinghui|last4=Gill|first4=Ammara|last5=Prasad|first5=Vinay|title=Distinctive clinical characteristics of malignant mesothelioma in young patients|journal=Oncotarget|volume=6|issue=18|year=2015|pages=16766–16773|issn=1949-2553|doi=10.18632/oncotarget.4414}}</ref>


===Age===
===Age===
The incidence of mesothelioma increases with age; the median age at diagnosis for pleural mesothelioma and peritoneal mesothelioma are 78 years and 68 years, respectively.<ref name="ThomasChen2015">{{cite journal|last1=Thomas|first1=Anish|last2=Chen|first2=Yuanbin|last3=Yu|first3=Tinghui|last4=Gill|first4=Ammara|last5=Prasad|first5=Vinay|title=Distinctive clinical characteristics of malignant mesothelioma in young patients|journal=Oncotarget|volume=6|issue=18|year=2015|pages=16766–16773|issn=1949-2553|doi=10.18632/oncotarget.4414}}</ref>
*Males are more commonly affected with mesothelioma than females. The male to female ratio is approximately 3 to 1.<ref name="epidemiologymesothelioma1">Mesothelioma. CGMH.ORG 2016. https://www1.cgmh.org.tw/intr/intr5/c6700/OBGYN/f/web/Mesothelioma/index.htm. Accessed on February 15, 2016</ref>
*The [[incidence]] of mesothelioma increases with age; the median age at diagnosis for [[pleural]] mesothelioma and peritoneal mesothelioma are 74 years and 68 years, respectively.<ref name="ThomasChen2015">{{cite journal|last1=Thomas|first1=Anish|last2=Chen|first2=Yuanbin|last3=Yu|first3=Tinghui|last4=Gill|first4=Ammara|last5=Prasad|first5=Vinay|title=Distinctive clinical characteristics of malignant mesothelioma in young patients|journal=Oncotarget|volume=6|issue=18|year=2015|pages=16766–16773|issn=1949-2553|doi=10.18632/oncotarget.4414}}</ref>
 
===Race===
*There is no racial predilection to mesothelioma.<ref name="epidemiologymesothelioma1">Mesothelioma. CGMH.ORG 2016. https://www1.cgmh.org.tw/intr/intr5/c6700/OBGYN/f/web/Mesothelioma/index.htm. Accessed on February 15, 2016</ref>


==References==
==References==
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[[Category:Mature chapter]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
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Latest revision as of 16:09, 25 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fatima Shaukat, MD [2]Parminder Dhingra, M.D. [3], Sujit Routray, M.D. [4]

Overview

Mesothelioma is a rare disease which accounts for 5-28% of all malignancies that involve the pleura. The incidence of mesothelioma is estimated to be 3,000 cases annually. The incidence of pleural mesothelioma is approximately 1 per 100,000 individuals in the United States. Males are more commonly affected with mesothelioma than females. The male to female ratio is approximately 3 to 1. The incidence of mesothelioma increases with age; the median age at diagnosis for pleural mesothelioma and peritoneal mesothelioma are 74 years and 68 years, respectively. There is no racial predilection to mesothelioma.

Epidemiology and Demographics

Prevalence

  • Mesothelioma is a rare disease which accounts for 5-28% of all malignancies that involve the pleura.[1]

Incidence

  • The incidence of mesothelioma is estimated to be 3,000 cases annually.[2]
  • The incidence of pleural mesothelioma is approximately 1 per 100,000 individuals in the United States.[3]
  • The incidence of pleural mesothelioma is approximately 1.2 per 100,000 individuals in Canada.[3]
  • The incidence of mesothelioma has decreased over several decades in the United States coincident with diminishing occupational asbestos exposure and has remained stable since 2003.[4]

Age

  • Males are more commonly affected with mesothelioma than females. The male to female ratio is approximately 3 to 1.[1]
  • The incidence of mesothelioma increases with age; the median age at diagnosis for pleural mesothelioma and peritoneal mesothelioma are 74 years and 68 years, respectively.[4]

Race

  • There is no racial predilection to mesothelioma.[1]

References

  1. 1.0 1.1 1.2 Epidemiology of mesothelioma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/mesothelioma. Accessed on February 8, 2016
  2. Philip A. Rascoe, Xiaobo X. Cao and W. Roy Smythe (2012). Molecular Pathogenesis of Malignant Pleural Mesothelioma, Mesotheliomas - Synonyms and Definition, Epidemiology, Etiology, Pathogenesis, Cyto-Histopathological Features, Clinic, Diagnosis, Treatment, Prognosis, Dr Alexander Zubritsky (Ed.), ISBN: 978-953-307-845-8, InTech, Available from: http://www.intechopen.com/books/mesotheliomas-synonyms-and-definition-epidemiology-etiology-pathogenesis-cyto-histopathological-features-clinic-diagnosis-treatment-prognosis/molecular-pathogenesis-of-malignant-pleural-mesothelioma
  3. 3.0 3.1 Saint-Pierre, Mathieu D.; Pease, Christopher; Mithoowani, Hamid; Zhang, Tinghua; Nicholas, Garth A.; Laurie, Scott A.; Wheatley-Price, Paul (2015). "Malignant Pleural Mesothelioma Outcomes in the Era of Combined Platinum and Folate Antimetabolite Chemotherapy". Lung Cancer International. 2015: 1–7. doi:10.1155/2015/590148. ISSN 2090-3197.
  4. 4.0 4.1 Thomas, Anish; Chen, Yuanbin; Yu, Tinghui; Gill, Ammara; Prasad, Vinay (2015). "Distinctive clinical characteristics of malignant mesothelioma in young patients". Oncotarget. 6 (18): 16766–16773. doi:10.18632/oncotarget.4414. ISSN 1949-2553.


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