Primary central nervous system lymphoma classification: Difference between revisions
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==Overview== | ==Overview== | ||
Primary | Primary CNS lymphomas are extranodal, malignant non-Hodgkin lymphomas of the diffuse large B-cell type that are confined to the brain, eyes, leptomeninges, or spinal cord, in the absence of systemic lymphoma. Primary CNS lymphomas are estimated to account for up to 1% of all lymphomas, 4–6% of all extranodal lymphomas, and about 3% of all CNS tumours. After a continuous rise in the incidence of primary CNS lymphoma during the 1980s and 1990s, epidemiological data in high-income countries show a decrease in incidence, particularly among young patients with AIDS. | ||
==Classification== | ==Classification== | ||
Primary central nervous system lymphoma may be classified according to the site of involvement of the central nervous system into 3 groups:<ref name=classifdicationprimarycnslymphoma1>CNS lymphoma. Dr Henry Knipe and Dr Yuranga Weerakkody et al. Radiopaedia 2016. http://radiopaedia.org/articles/cns-lymphoma-1. Accessed on February 17, 2016</ref> | Primary central nervous system lymphoma may be classified according to the site of involvement of the central nervous system into 3 groups:<ref name=classifdicationprimarycnslymphoma1>CNS lymphoma. Dr Henry Knipe and Dr Yuranga Weerakkody et al. Radiopaedia 2016. http://radiopaedia.org/articles/cns-lymphoma-1. Accessed on February 17, 2016</ref> | ||
*Parenchymal | *'''Parenchymal''' | ||
:*Non-Hodgkin B cell type / diffuse large B-cell non-Hodgkin's lymphoma ('''most common''') | :*Non-Hodgkin B cell type / diffuse large B-cell non-Hodgkin's lymphoma ('''most common''') | ||
:*Non-Hodgkin T cell type | :*Non-Hodgkin T cell type | ||
:*Primary CNS involvement with Hodgkin disease | :*Primary CNS involvement with Hodgkin disease | ||
*Intravascular lymphoma | *'''Intravascular lymphoma''' | ||
*Primary leptomeningeal lymphoma | *'''Primary leptomeningeal lymphoma''' | ||
:*Primary dural lymphoma | :*Primary dural lymphoma | ||
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Latest revision as of 03:45, 8 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Primary CNS lymphomas are extranodal, malignant non-Hodgkin lymphomas of the diffuse large B-cell type that are confined to the brain, eyes, leptomeninges, or spinal cord, in the absence of systemic lymphoma. Primary CNS lymphomas are estimated to account for up to 1% of all lymphomas, 4–6% of all extranodal lymphomas, and about 3% of all CNS tumours. After a continuous rise in the incidence of primary CNS lymphoma during the 1980s and 1990s, epidemiological data in high-income countries show a decrease in incidence, particularly among young patients with AIDS.
Classification
Primary central nervous system lymphoma may be classified according to the site of involvement of the central nervous system into 3 groups:[1]
- Parenchymal
- Non-Hodgkin B cell type / diffuse large B-cell non-Hodgkin's lymphoma (most common)
- Non-Hodgkin T cell type
- Primary CNS involvement with Hodgkin disease
- Intravascular lymphoma
- Primary leptomeningeal lymphoma
- Primary dural lymphoma
References
- ↑ CNS lymphoma. Dr Henry Knipe and Dr Yuranga Weerakkody et al. Radiopaedia 2016. http://radiopaedia.org/articles/cns-lymphoma-1. Accessed on February 17, 2016