Mast cell tumor classification: Difference between revisions
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{{CMG}};{{AE}} {{PSK}} | {{CMG}};{{AE}} {{PSK}} | ||
==Overview== | ==Overview== | ||
Based on the affected organ(s), mast cell tumor may be classified into either cutaneous mastocytosis or systemic mastocytosis. Mast cell tumor may be classified into seven subtypes based on [[WHO]] classification system. | Based on the affected organ(s), mast cell tumor may be classified into either cutaneous mastocytosis or systemic mastocytosis. Mast cell tumor may be classified into seven subtypes based on [[WHO]] classification system.<ref name="pmid17488167">{{cite journal| author=Patnaik MM, Rindos M, Kouides PA, Tefferi A, Pardanani A| title=Systemic mastocytosis: a concise clinical and laboratory review. | journal=Arch Pathol Lab Med | year= 2007 | volume= 131 | issue= 5 | pages= 784-91 | pmid=17488167 | doi=10.1043/1543-2165(2007)131[784:SMACCA]2.0.CO;2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17488167 }} </ref> | ||
==Classification== | ==Classification== | ||
'''Based on the affected organ(s), mast cell tumor may be classified into two subtypes''': | '''Based on the affected organ(s), mast cell tumor may be classified into two subtypes''': | ||
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:*Limited to the skin where mast cells infiltrate the skin | :*Limited to the skin where mast cells infiltrate the skin | ||
*Systemic mastocytosis | *Systemic mastocytosis | ||
:*Systemic mastocytosis is caused by mast cells accumulating in the tissues and can affect organs such as the [[liver]], [[spleen]], [[bone marrow]], and small intestine | :*Systemic mastocytosis is caused by mast cells accumulating in the tissues and can affect organs such as the [[liver]], [[spleen]], [[bone marrow]], and small intestine | ||
*Localized mastocytosis | |||
'''Mast cell tumor may be classified according to WHO classification into seven subtypes''':<ref name="pmid17488167">{{cite journal| author=Patnaik MM, Rindos M, Kouides PA, Tefferi A, Pardanani A| title=Systemic mastocytosis: a concise clinical and laboratory review. | journal=Arch Pathol Lab Med | year= 2007 | volume= 131 | issue= 5 | pages= 784-91 | pmid=17488167 | doi=10.1043/1543-2165(2007)131[784:SMACCA]2.0.CO;2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17488167 }} </ref> | '''Mast cell tumor may be classified according to WHO classification into seven subtypes''':<ref name="pmid17488167">{{cite journal| author=Patnaik MM, Rindos M, Kouides PA, Tefferi A, Pardanani A| title=Systemic mastocytosis: a concise clinical and laboratory review. | journal=Arch Pathol Lab Med | year= 2007 | volume= 131 | issue= 5 | pages= 784-91 | pmid=17488167 | doi=10.1043/1543-2165(2007)131[784:SMACCA]2.0.CO;2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17488167 }} </ref> | ||
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[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Pathology]] | [[Category:Pathology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Hematology]] | |||
[[Category:Immunology]] | |||
Latest revision as of 16:37, 9 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Based on the affected organ(s), mast cell tumor may be classified into either cutaneous mastocytosis or systemic mastocytosis. Mast cell tumor may be classified into seven subtypes based on WHO classification system.[1]
Classification
Based on the affected organ(s), mast cell tumor may be classified into two subtypes:
- Cutaneous mastocytosis
- Limited to the skin where mast cells infiltrate the skin
- Systemic mastocytosis
- Systemic mastocytosis is caused by mast cells accumulating in the tissues and can affect organs such as the liver, spleen, bone marrow, and small intestine
- Localized mastocytosis
Mast cell tumor may be classified according to WHO classification into seven subtypes:[1]
- Cutaneous mastocytosis
- Urticaria pigmentosa
- Maculopapular cutaneous mastocytosis
- Diffuse cutaneous mastocytosis
- Mastocytoma of skin
- Indolent systemic mastocytosis
- Smoldering systemic mastocytosis
- Isolated bone marrow mastocytosis
- Systemic mastocytosis with an associated (clonal) hematologic non–mast cell lineage disease
- Aggressive systemic mastocytosis
- Lymphadenopathic systemic mastocytosis with eosinophilia
- Mast cell leukemia
- Typical mast cell leukemia
- Aleukemic mast cell leukemia
- Mast cell sarcoma
- Extracutaneous mastocytoma
References
- ↑ 1.0 1.1 Patnaik MM, Rindos M, Kouides PA, Tefferi A, Pardanani A (2007). "Systemic mastocytosis: a concise clinical and laboratory review". Arch Pathol Lab Med. 131 (5): 784–91. doi:10.1043/1543-2165(2007)131[784:SMACCA]2.0.CO;2. PMID 17488167.