Pulmonary nodule imaging: Difference between revisions

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==Overview==
==Overview==
Conventional radiography is the initial method of choice for the evaluation of solitary pulmonary nodule. The evaluation and risk assessment of solitary pulmonary nodule will depend on several characteristics, such as: size, growth, shape, margin, air bronchogram sign, and attenuation. Further evaluation of solitary pulmonary lung nodule, should include enhanced CT scan or MRI imaging. Other imaging studies include [[PET]] scanning, which may be useful as a staging modality, detection of occult disease, and malignancy assessment.
Conventional radiography is the initial method of choice for the evaluation of pulmonary nodule. The evaluation and risk assessment of pulmonary nodule will depend on several characteristics, such as: size, growth, shape, margin, location, and attenuation. Further evaluation of solitary pulmonary lung nodule, should include enhanced CT scan or MRI imaging. Other imaging studies include [[PET]] scanning, which may be useful as a staging modality, detection of occult disease, and malignancy assessment.<ref name="pmid19835344">{{cite journal |vauthors=Albert RH, Russell JJ |title=Evaluation of the solitary pulmonary nodule |journal=Am Fam Physician |volume=80 |issue=8 |pages=827–31 |year=2009 |pmid=19835344 |doi= |url=}}</ref>


==Imaging==
==Imaging==


===Plain Radiograph===
The table below summarizes the radiological features suggestive of benign or malignant pulmonary nodules.<ref name="pmid19835344">{{cite journal |vauthors=Albert RH, Russell JJ |title=Evaluation of the solitary pulmonary nodule |journal=Am Fam Physician |volume=80 |issue=8 |pages=827–31 |year=2009 |pmid=19835344 |doi= |url=}}</ref>


*Conventional radiography is the initial method of choice for the evaluation of pulmonary nodule
{|style="border: 5px; font-size: 90%; margin: 5px; width: 1000px" align=center
*Conventional chest radiograph may also be helpful in the diagnosis of pulmonary nodule
!style="padding: 5px 5px; background: #4479BA; font-weight: bold; text-align:center;" colspan="3"|{{fontcolor|#FFF|''' Radiologic Features Suggestive of Benign or Malignant Pulmonary Nodules''' <br><SMALL> Adapted from American Academy of Family Physicians <ref name="CDC"> Solitary Pulmonary Nodule: Morphological Evaluation. http://pubs.rsna.org/doi/pdf/10.1148/radiographics.20.1.g00ja0343 Accessed on March 15, 2016 </ref></SMALL>}}
 
|valign=top|
===CT===
|+
 
|-
'''Calcification'''
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|'''Radiologic feature'''}} 
 
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|'''Benign'''}}
*Calcification patterns are commonly seen in granulomatous disease and hamartomas
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|'''Malignant'''}}
*Characteristic calcification patterns of pulmonary nodule, include:
|-
:*Diffuse
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;"| Size
:*Central
|style="padding: 5px 5px; background: #F5F5F5;"|< 5 mm
:*Laminated
|style="padding: 5px 5px; background: #F5F5F5;"|> 10 mm
:*Popcorn
|-
 
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;"| Border
'''Size'''
|style="padding: 5px 5px; background: #F5F5F5;"| Smooth
 
|style="padding: 5px 5px; background: #F5F5F5;"| Irregular or spiculated
*Different size ranges of pulmonary nodule, include:
|-
* Nodules less than 4mm
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;"| Density
* Nodules between 4mm and 7mm
|style="padding: 5px 5px; background: #F5F5F5;"| Dense, solid
* Nodules between 8mm and 20mm
|style="padding: 5px 5px; background: #F5F5F5;"| Nonsolid, “ground glass”
* Nodules more than 20mm
|-
 
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;"| Calcification
'''Growth'''
|style="padding: 5px 5px; background: #F5F5F5;"| Typically a benign feature, especially in “concentric,” “central,” “popcorn-like,” or “homogeneous” patterns
 
|style="padding: 5px 5px; background: #F5F5F5;"| Typically noncalcified, or “eccentric” calcification
'''Shape'''
|-
*Polygonal
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;"| Doubling time
*Circular
|style="padding: 5px 5px; background: #F5F5F5;"| Less than one month; more than one year
:*Spherical
|style="padding: 5px 5px; background: #F5F5F5;"| One month to one year
 
|}
'''Margins'''
*Lobulated or scalloped margins
:*Intermediate malignancy probability
*Smooth margins
*:Associated with nodule benignancy 
 
'''Attenuation'''
*Solid pulmonary nodules
:*Malignancy rate of only 7%
*Calcified pulmonary nodules
*Partly solid pulmonary nodules
:*Malignancy rate of 63%
*Ground glass pulmonary nodules
:*Malignancy rate of 18%
 
 
'''Contrast enhancement'''
 
* Contrast enhancement of pulmonary nodules may be useful to determine benign or malignant features
* Benign pulmonary nodules usually have a contrast enhancement less than 15 HU
 
 
On CT, radiological signs of pulmonary nodule, include:
*Corona radiata sign
:*Highly associated with malignancy
*Air bronchogram sign
:*Non-specific sign
 
===MRI===
 
 
==Gallery==
 
===Plain Radiograph===
 
<gallery widths="200px">
</gallery>
 
===CT===
<gallery widths="200px">
</gallery>
 
===MRI===
<gallery widths="200px">
</gallery>


==References==
==References==

Latest revision as of 21:35, 23 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Conventional radiography is the initial method of choice for the evaluation of pulmonary nodule. The evaluation and risk assessment of pulmonary nodule will depend on several characteristics, such as: size, growth, shape, margin, location, and attenuation. Further evaluation of solitary pulmonary lung nodule, should include enhanced CT scan or MRI imaging. Other imaging studies include PET scanning, which may be useful as a staging modality, detection of occult disease, and malignancy assessment.[1]

Imaging

The table below summarizes the radiological features suggestive of benign or malignant pulmonary nodules.[1]

Radiologic Features Suggestive of Benign or Malignant Pulmonary Nodules
Adapted from American Academy of Family Physicians [2]
Radiologic feature Benign Malignant
Size < 5 mm > 10 mm
Border Smooth Irregular or spiculated
Density Dense, solid Nonsolid, “ground glass”
Calcification Typically a benign feature, especially in “concentric,” “central,” “popcorn-like,” or “homogeneous” patterns Typically noncalcified, or “eccentric” calcification
Doubling time Less than one month; more than one year One month to one year

References

  1. 1.0 1.1 Albert RH, Russell JJ (2009). "Evaluation of the solitary pulmonary nodule". Am Fam Physician. 80 (8): 827–31. PMID 19835344.
  2. Solitary Pulmonary Nodule: Morphological Evaluation. http://pubs.rsna.org/doi/pdf/10.1148/radiographics.20.1.g00ja0343 Accessed on March 15, 2016


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