Osteomyelitis history and symptoms: Difference between revisions

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{{Osteomyelitis}}
{{Osteomyelitis}}
{{CMG}} {{AE}} {{NRM}}
{{CMG}} {{AE}} {{NRM}},{{MehdiP}}


==Overview==
==Overview==
The patient's history is important in establishing a diagnosis of osteomyelitis. Common history findings include [[intravenous drug use]], [[bacteremia]], recent open [[fracture]] or [[surgery]], and [[diabetes]]. Common symptoms include [[chills]], [[fever]], [[malaise]], local pain and warmth, [[edema]], and [[erythema]]. Fever is typically absent in diabetic patients with osteomyelitis secondary to vascular insufficiency and in patients with infected [[prosthesis]]. The presence of a '''draining sinus tract''' is pathognomonic of chronic osteomyelitis.


==History and Symptoms==
==History and Symptoms==
===Patient History===
===Patient History===
====Hematogenous Osteomyelitis====
A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient based on specific types of osteomyelitis include:
*Intravenous drug use
*Hematogenous Osteomyelitis:
*Urinary catheter use
:*[[Intravenous drug use]]<ref name="LewWaldvogel1997">{{cite journal|last1=Lew|first1=Daniel P.|last2=Waldvogel|first2=Francis A.|title=Osteomyelitis|journal=New England Journal of Medicine|volume=336|issue=14|year=1997|pages=999–1007|issn=0028-4793|doi=10.1056/NEJM199704033361406}}</ref>
*[[Bacteremia]]
:*[[Urinary catheter]] use
:*[[Bacteremia]]


====Contiguous-focus Osteomyelitis====
*Contiguous-focus Osteomyelitis:
*Recent open fracture
:*Recent open [[fracture]]
*Recent orthopedic surgery
:*Recent [[surgery]], especially [[orthopedic surgery]]
*Prosthesis
:*[[Prosthesis]]


====Osteomyelitis Secondary to Vascular Insufficiency====
*Osteomyelitis secondary to vascular insufficiency:
*[[Diabetes]]
:*[[Diabetes]]<ref name="CaputoCavanagh1994">{{cite journal|last1=Caputo|first1=Gregory M.|last2=Cavanagh|first2=Peter R.|last3=Ulbrecht|first3=Jan S.|last4=Gibbons|first4=Gary W.|last5=Karchmer|first5=Adolf W.|title=Assessment and Management of Foot Disease in Patients with Diabetes|journal=New England Journal of Medicine|volume=331|issue=13|year=1994|pages=854–860|issn=0028-4793|doi=10.1056/NEJM199409293311307}}</ref>
:*Diabetic patients with soft-tissue inflammation or skin ulcers in the feet
:*Diabetic patients with soft-tissue inflammation or skin [[ulcers]] in the feet


===Common symptoms===
===Common symptoms===
*Chills
*Systemic:<ref name="LewWaldvogel2004">{{cite journal|last1=Lew|first1=Daniel P|last2=Waldvogel|first2=Francis A|title=Osteomyelitis|journal=The Lancet|volume=364|issue=9431|year=2004|pages=369–379|issn=01406736|doi=10.1016/S0140-6736(04)16727-5}}</ref><ref name="pmid11880745">{{cite journal |vauthors=Vazquez M |title=Osteomyelitis in children |journal=Curr. Opin. Pediatr. |volume=14 |issue=1 |pages=112–5 |year=2002 |pmid=11880745 |doi= |url=}}</ref>
*[[Fever]]
:*[[Chills]]
*[[Malaise]]
:*[[Headache]]
*Local pain
:*[[Fatigue]]
*[[Edema]]
:*[[Anorexia]]
*[[Erythema]]
:*[[Fever]]
*Warmth
:*[[Malaise]]
*Local:
:*Pain
:*[[Edema]]
:*[[Erythema]]
:*Warmth


 
===Special Considerations===
* Hematogenous long-bone osteomyelitis
*Diabetic patients with osteomyelitis secondary to [[vascular insufficiency]] typically do not have fever or inflammation.<ref name="pmid1908030">{{cite journal |vauthors=Newman LG, Waller J, Palestro CJ, Schwartz M, Klein MJ, Hermann G, Harrington E, Harrington M, Roman SH, Stagnaro-Green A |title=Unsuspected osteomyelitis in diabetic foot ulcers. Diagnosis and monitoring by leukocyte scanning with indium in 111 oxyquinoline |journal=JAMA |volume=266 |issue=9 |pages=1246–51 |year=1991 |pmid=1908030 |doi= |url=}}</ref>
:* Abrupt onset of high [[fever]] (fever is present in only 50% of neonates with osteomyelitis)
*Diabetic patients with advanced [[neuropathy]] may not feel pain.
:* [[Fatigue]]
*Fever is typically absent in patients with infected prosthesis.
:* [[Irritability]]
*Patients with vertebral osteomyelitis may have generalized neck and back pain.
:* [[Malaise]]
*The presence of a '''draining sinus tract''' is '''pathognomonic''' of chronic osteomyelitis.
:* Restriction of movement (pseudoparalysis of limb in neonates)
:* Local [[edema]], [[erythema]], and tenderness
* Hematogenous vertebral osteomyelitis
:* Insidious onset
:* History of an acute bacteremic episode
:* May be associated with contiguous vascular insufficiency
:* Local [[edema]], [[erythema]], and tenderness
:* Failure of a young child to sit up normally
* Chronic osteomyelitis
:* Non-healing ulcer
:* Sinus tract drainage
:* Chronic [[fatigue]]
:* [[Malaise]]


==References==
==References==
{{Reflist|2}}


{{Reflist|2}}
[[Category:Needs overview]]
[[Category:Orthopedics]]
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[[Category:Bacterial diseases]]
[[Category:Emergency mdicine]]
[[Category:Skeletal disorders]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Disease]]
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Latest revision as of 23:28, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nate Michalak, B.A.,Seyedmahdi Pahlavani, M.D. [2]

Overview

The patient's history is important in establishing a diagnosis of osteomyelitis. Common history findings include intravenous drug use, bacteremia, recent open fracture or surgery, and diabetes. Common symptoms include chills, fever, malaise, local pain and warmth, edema, and erythema. Fever is typically absent in diabetic patients with osteomyelitis secondary to vascular insufficiency and in patients with infected prosthesis. The presence of a draining sinus tract is pathognomonic of chronic osteomyelitis.

History and Symptoms

Patient History

A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient based on specific types of osteomyelitis include:

  • Hematogenous Osteomyelitis:
  • Contiguous-focus Osteomyelitis:
  • Osteomyelitis secondary to vascular insufficiency:
  • Diabetes[2]
  • Diabetic patients with soft-tissue inflammation or skin ulcers in the feet

Common symptoms

  • Local:

Special Considerations

  • Diabetic patients with osteomyelitis secondary to vascular insufficiency typically do not have fever or inflammation.[5]
  • Diabetic patients with advanced neuropathy may not feel pain.
  • Fever is typically absent in patients with infected prosthesis.
  • Patients with vertebral osteomyelitis may have generalized neck and back pain.
  • The presence of a draining sinus tract is pathognomonic of chronic osteomyelitis.

References

  1. Lew, Daniel P.; Waldvogel, Francis A. (1997). "Osteomyelitis". New England Journal of Medicine. 336 (14): 999–1007. doi:10.1056/NEJM199704033361406. ISSN 0028-4793.
  2. Caputo, Gregory M.; Cavanagh, Peter R.; Ulbrecht, Jan S.; Gibbons, Gary W.; Karchmer, Adolf W. (1994). "Assessment and Management of Foot Disease in Patients with Diabetes". New England Journal of Medicine. 331 (13): 854–860. doi:10.1056/NEJM199409293311307. ISSN 0028-4793.
  3. Lew, Daniel P; Waldvogel, Francis A (2004). "Osteomyelitis". The Lancet. 364 (9431): 369–379. doi:10.1016/S0140-6736(04)16727-5. ISSN 0140-6736.
  4. Vazquez M (2002). "Osteomyelitis in children". Curr. Opin. Pediatr. 14 (1): 112–5. PMID 11880745.
  5. Newman LG, Waller J, Palestro CJ, Schwartz M, Klein MJ, Hermann G, Harrington E, Harrington M, Roman SH, Stagnaro-Green A (1991). "Unsuspected osteomyelitis in diabetic foot ulcers. Diagnosis and monitoring by leukocyte scanning with indium in 111 oxyquinoline". JAMA. 266 (9): 1246–51. PMID 1908030.