Heparin-induced thrombocytopenia CT: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Heparin-induced thrombocytopenia}} | {{Heparin-induced thrombocytopenia}} | ||
{{CMG}}; | {{CMG}}; {{shyam}} | ||
==Overview== | ==Overview== | ||
CT scan may be helpful in the diagnosis of complications of heparin induced [[thrombocytopenia]], such as [[stroke]], [[pulmonary embolism]], [[mesenteric ischemia]] | |||
==CT== | |||
There are no CT scan findings associated with heparin induced [[thrombocytopenia]]. However, a CT scan may be helpful in the diagnosis of complications of heparin induced [[thrombocytopenia]], which include: | |||
*[[Stroke]] | |||
*[[Pulmonary embolism]] | |||
*[[Mesenteric ischemia]] | |||
*Intraabdominal or [[retroperitoneal bleeding]] | |||
*Acute limb [[ischemia]] | |||
==CT== | * '''CT of the head''' in a patient with thrombotic [[stroke]] can show hypodensity suggestive of infarcted brain tissue. Alternatively, intracranial bleeding from thrombocytopenia will present radiographically as a hyperdensity on CT.<ref name="pmid22315270">{{cite journal| author=Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S et al.| title=Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. | journal=Chest | year= 2012 | volume= 141 | issue= 2 Suppl | pages= e495S-e530S | pmid=22315270 | doi=10.1378/chest.11-2303 | pmc=3278058 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22315270 }} </ref> | ||
* '''CT of the chest''' in a patient with [[pulmonary embolism]] from HIT can show Hampton's hump, Westermark's sign, or Fleischner's sign, similar to a chest X-ray.<ref name="pmid22315270">{{cite journal| author=Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S et al.| title=Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. | journal=Chest | year= 2012 | volume= 141 | issue= 2 Suppl | pages= e495S-e530S | pmid=22315270 | doi=10.1378/chest.11-2303 | pmc=3278058 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22315270 }} </ref> | |||
* '''CT of the abdomen or pelvis''' in a patient with [[mesenteric ischemia]] can show evidence of bowel necrosis. A retroperitoneal bleed or intraabdominal bleed from [[thrombocytopenia]] will show hyperdensity in the area of the bleeding. CT of the abdomen and pelvis can also be used to visualize bilateral adrenal hemorrhage, which has been shown to be a unique clinical manifestation of HIT.<ref name="pmid21242799">{{cite journal| author=Rosenberger LH, Smith PW, Sawyer RG, Hanks JB, Adams RB, Hedrick TL| title=Bilateral adrenal hemorrhage: the unrecognized cause of hemodynamic collapse associated with heparin-induced thrombocytopenia. | journal=Crit Care Med | year= 2011 | volume= 39 | issue= 4 | pages= 833-8 | pmid=21242799 | doi=10.1097/CCM.0b013e318206d0eb | pmc=3101312 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21242799 }} </ref> | |||
* '''CT of the extremities''' in a patient with acute limb ischemic can show evidence of an ischemic limb. CT should be done with a runoff study to visualize the passage of dye through the arterial or venous circulation of the extremity. | |||
== | ==Reference== | ||
{{ | {{Reflist|2}} | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
{{WS}} | |||
{{WH}} |
Latest revision as of 16:34, 8 August 2018
Heparin-induced thrombocytopenia |
Differentiating Heparin-induced thrombocytopenia from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Heparin-induced thrombocytopenia CT On the Web |
American Roentgen Ray Society Images of Heparin-induced thrombocytopenia CT |
Directions to Hospitals Treating Heparin-induced thrombocytopenia |
Risk calculators and risk factors for Heparin-induced thrombocytopenia CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Shyam Patel [2]
Overview
CT scan may be helpful in the diagnosis of complications of heparin induced thrombocytopenia, such as stroke, pulmonary embolism, mesenteric ischemia
CT
There are no CT scan findings associated with heparin induced thrombocytopenia. However, a CT scan may be helpful in the diagnosis of complications of heparin induced thrombocytopenia, which include:
- Stroke
- Pulmonary embolism
- Mesenteric ischemia
- Intraabdominal or retroperitoneal bleeding
- Acute limb ischemia
- CT of the head in a patient with thrombotic stroke can show hypodensity suggestive of infarcted brain tissue. Alternatively, intracranial bleeding from thrombocytopenia will present radiographically as a hyperdensity on CT.[1]
- CT of the chest in a patient with pulmonary embolism from HIT can show Hampton's hump, Westermark's sign, or Fleischner's sign, similar to a chest X-ray.[1]
- CT of the abdomen or pelvis in a patient with mesenteric ischemia can show evidence of bowel necrosis. A retroperitoneal bleed or intraabdominal bleed from thrombocytopenia will show hyperdensity in the area of the bleeding. CT of the abdomen and pelvis can also be used to visualize bilateral adrenal hemorrhage, which has been shown to be a unique clinical manifestation of HIT.[2]
- CT of the extremities in a patient with acute limb ischemic can show evidence of an ischemic limb. CT should be done with a runoff study to visualize the passage of dye through the arterial or venous circulation of the extremity.
Reference
- ↑ 1.0 1.1 Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S; et al. (2012). "Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 141 (2 Suppl): e495S–e530S. doi:10.1378/chest.11-2303. PMC 3278058. PMID 22315270.
- ↑ Rosenberger LH, Smith PW, Sawyer RG, Hanks JB, Adams RB, Hedrick TL (2011). "Bilateral adrenal hemorrhage: the unrecognized cause of hemodynamic collapse associated with heparin-induced thrombocytopenia". Crit Care Med. 39 (4): 833–8. doi:10.1097/CCM.0b013e318206d0eb. PMC 3101312. PMID 21242799.