Hemolytic anemia history and symptoms: Difference between revisions

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{{Hemolytic anemia}}
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==Overview==
==Overview==
The symptoms of [[hemolysis]] mostly relate to (1) [[red blood cell]] loss and (2) release of [[hemoglobin]] and its breakdown products into the [[circulation]]. The breakdown products of [[hemoglobin]] will accumulate in the [[blood]] causing [[jaundice]] and be excreted in the [[urine]] causing the urine to become dark brown in color.


==Symptoms==
==Symptoms==
 
Some of the symptoms include<ref name="pmid26696800">{{cite journal| author=Packman CH| title=The Clinical Pictures of Autoimmune Hemolytic Anemia. | journal=Transfus Med Hemother | year= 2015 | volume= 42 | issue= 5 | pages= 317-24 | pmid=26696800 | doi=10.1159/000440656 | pmc=4678314 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26696800  }} </ref>:
The breakdown products of [[hemoglobin]] will accumulate in the blood causing [[jaundice]] and be excreted in the urine causing the urine to become dark brown in color.


*[[Chills]]
*[[Chills]]
*[[Dark urine]]
*[[Dark urine]]
*Enlarged [[spleen]]
*Early [[satiety]] from enlarged [[spleen]]
*[[Fatigue]]
*[[Fatigue]]
*[[Fever]]
*[[Fever]]
*Pale skin color ([[pallor]])
*Pale skin color ([[pallor]])
*Rapid [[heart rate]]
*[[Palpitations]] from elevated [[heart rate]]
*[[Shortness of breath]]
*[[Shortness of breath]]
*Yellow skin color ([[jaundice]])
*Yellow [[skin]] color ([[jaundice]])


==Past Medical History==
==Past Medical History==


Certain aspects of the medical history can suggest a cause for hemolysis (drugs, [[fava bean]] or other sensitivity, [[heart valve prosthesis|prosthetic heart valve]], or another medical illness).
Certain aspects of the medical history can suggest a cause for [[hemolysis]].
*Presence of [[prosthetic heart valve]]
*Presence of other [[comorbidities]] like [[chronic lymphocytic leukemia]]
*Presence of [[autoimmune]] conditions
 
*Use of [[drugs]]
*Consumption of [[Fava bean|fava beans]]


==References==
==References==

Latest revision as of 13:59, 31 October 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Shyam Patel [2]

Overview

The symptoms of hemolysis mostly relate to (1) red blood cell loss and (2) release of hemoglobin and its breakdown products into the circulation. The breakdown products of hemoglobin will accumulate in the blood causing jaundice and be excreted in the urine causing the urine to become dark brown in color.

Symptoms

Some of the symptoms include[1]:

Past Medical History

Certain aspects of the medical history can suggest a cause for hemolysis.

References

  1. Packman CH (2015). "The Clinical Pictures of Autoimmune Hemolytic Anemia". Transfus Med Hemother. 42 (5): 317–24. doi:10.1159/000440656. PMC 4678314. PMID 26696800.

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