Differentiating urticaria from other diseases: Difference between revisions

	Urticaria Microchapters
Home
Patient Information
Overview
Classification
Pathophysiology
Causes
Differentiating Urticaria from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Primary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Differentiating urticaria from other diseases On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Differentiating urticaria from other diseases All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Differentiating urticaria from other diseases
CDC on Differentiating urticaria from other diseases
Differentiating urticaria from other diseases in the news
Blogs on Differentiating urticaria from other diseases
Directions to Hospitals Treating Urticaria
Risk calculators and risk factors for Differentiating urticaria from other diseases

VisualWikitext

Latest revision as of 15:32, 28 January 2021

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2]

Overview

It is critical to differentiate urticaria from other similar disorders to utilize the best approach for the treatment. Hereditary or acquired deficiency of complement factor C1, cutaneous mastocytosis such as urticaria pigmentosa, certain malignancies, connective tissue diseases, angioedema and exercise‐induced anaphylaxis are some of the differential diagnosis of urticaria.

Differentiating Urticaria from other Diseases

Hereditary or acquired deficiency of complement factor C1
Cutaneous mastocytosis/urticaria pigmentosa
Malignancy
Exercise‐induced anaphylaxis^[1]
Connective tissue diseases
Photosensitive diseases
Poison ivy contact dermatitis: The rash that develops from poison ivy, poison oak, and poison sumac contact are commonly mistaken for urticaria. This rash is caused by contact with urushiol and results in a form of contact dermatitis called urushiol-induced contact dermatitis.
Angioedema:
- Although it might be related to urticaria, angioedema occurs due to swelling of the lower layers of dermis.^[2]
- Edema can occur around the mouth, in the throat, in the abdomen, or in other locations. Urticaria and angioedema sometimes occur together in response to an allergen and should be a concern in severe cases because angioedema of the throat can be fatal.
A possible differential diagnosis for diseases that cause urticaria, and rash include:
Table below differentiates some of the aforementioned conditions:


Disease name	Age of onset	Signs/Symptoms	Diagnostic feature(s)	Other features
Cold Contact Urticaria^[3]^[4]	Early adulthood	Urticarial skin eruption after exposure to cold Urticaria and/or angioedema affects areas only in contact with cold Systemic symptoms may be present in case of extensive skin involvement (such as anaphylaxis)	Ice cube test is positive	The wheal appears within 5 minutes of cold contact
Familial Cold Autoinflammatory Syndrome^[5]	Infancy, but may be delayed until adulthood	Non-pruritic urticarial rash Fever Headache Fatigue Conjunctivitis	Ice cube test is negative	Cold-induced rash Skin biopsy shows increased neutrophils at the eccrine coils
Schnitzler syndrome^[6]	Middle age	Chronic urticarial rash Fever Arthralgia Bone pain	Monoclonal gammopathy	Rash is the presenting sign Neutrophillic infiltrate in dermis Dermographism
Deficiency in Interleukin-1 Receptor Antagonist^[7]	Infancy	Pustular rash Bone pain Swollen joints Aphthous ulcers	Occurs due to mutation in IL1RN gene Pustular rash similar to pustular psoriasis	Epidermal neutrophilic pustules at hair follicles Pathergy Hyperkeratosis and acanthosis High neutrophil infiltrate of the dermis
Systemic-Onset Juvenile Idiopathic Arthritis^[8]	2-16 years of age	High fever Arthralgia Generalized lymphadenopathy Splenomegaly	Evanescent rash Bright salmon-pink Morbilliform, macular rash Rash presents with onset of fever	May cause amyloidosis
Adult-Onset Still’s Disease^[9]	16-35 years May affect all ages	High spiking fever Joint pain Skin rash Lymphadenopathy Splenomegaly	Evanescent salmon-colored bumpy rash Pruritic rash on the proximal limbs and trunk	More commonly seen among women May cause destructive arthritis

References

↑ Zuberbier T (2003). "Urticaria". Allergy. 58 (12): 1224–34. doi:10.1046/j.1398-9995.2003.00327.x. PMID 14616095.
↑ "Hives (Urticaria and Angioedema)". 2006-03-01. Retrieved 2007-08-24.
↑ Siebenhaar, F.; Weller, K.; Mlynek, A.; Magerl, M.; Altrichter, S.; Vieira dos Santos, R.; Maurer, M.; Zuberbier, T. (2007). "Acquired cold urticaria: clinical picture and update on diagnosis and treatment". Clinical and Experimental Dermatology. 32 (3): 241–245. doi:10.1111/j.1365-2230.2007.02376.x. ISSN 0307-6938.
↑ Krause, Karoline; Zuberbier, Torsten; Maurer, Marcus (2010). "Modern Approaches to the Diagnosis and Treatment of Cold Contact Urticaria". Current Allergy and Asthma Reports. 10 (4): 243–249. doi:10.1007/s11882-010-0121-3. ISSN 1529-7322.
↑ Kastner, D. L. (2005). "Hereditary Periodic Fever Syndromes". Hematology. 2005 (1): 74–81. doi:10.1182/asheducation-2005.1.74. ISSN 1520-4391.
↑ de Koning, Heleen D.; Bodar, Evelien J.; van der Meer, Jos W.M.; Simon, Anna (2007). "Schnitzler Syndrome: Beyond the Case Reports: Review and Follow-Up of 94 Patients with an Emphasis on Prognosis and Treatment". Seminars in Arthritis and Rheumatism. 37 (3): 137–148. doi:10.1016/j.semarthrit.2007.04.001. ISSN 0049-0172.
↑ Aksentijevich, Ivona; Masters, Seth L.; Ferguson, Polly J.; Dancey, Paul; Frenkel, Joost; van Royen-Kerkhoff, Annet; Laxer, Ron; Tedgård, Ulf; Cowen, Edward W.; Pham, Tuyet-Hang; Booty, Matthew; Estes, Jacob D.; Sandler, Netanya G.; Plass, Nicole; Stone, Deborah L.; Turner, Maria L.; Hill, Suvimol; Butman, John A.; Schneider, Rayfel; Babyn, Paul; El-Shanti, Hatem I.; Pope, Elena; Barron, Karyl; Bing, Xinyu; Laurence, Arian; Lee, Chyi-Chia R.; Chapelle, Dawn; Clarke, Gillian I.; Ohson, Kamal; Nicholson, Marc; Gadina, Massimo; Yang, Barbara; Korman, Benjamin D.; Gregersen, Peter K.; van Hagen, P. Martin; Hak, A. Elisabeth; Huizing, Marjan; Rahman, Proton; Douek, Daniel C.; Remmers, Elaine F.; Kastner, Daniel L.; Goldbach-Mansky, Raphaela (2009). "An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist". New England Journal of Medicine. 360 (23): 2426–2437. doi:10.1056/NEJMoa0807865. ISSN 0028-4793.
↑ Gurion, R.; Lehman, T. J. A.; Moorthy, L. N. (2012). "Systemic Arthritis in Children: A Review of Clinical Presentation and Treatment". International Journal of Inflammation. 2012: 1–16. doi:10.1155/2012/271569. ISSN 2090-8040.
↑ Efthimiou, P (2006). "Diagnosis and management of adult onset Still's disease". Annals of the Rheumatic Diseases. 65 (5): 564–572. doi:10.1136/ard.2005.042143. ISSN 0003-4967.

Template:WH Template:WS

[pmid14616095-1] Zuberbier T (2003). "Urticaria". Allergy. 58 (12): 1224–34. doi:10.1046/j.1398-9995.2003.00327.x. PMID 14616095.

[2] "Hives (Urticaria and Angioedema)". 2006-03-01. Retrieved 2007-08-24.

[SiebenhaarWeller2007-3] Siebenhaar, F.; Weller, K.; Mlynek, A.; Magerl, M.; Altrichter, S.; Vieira dos Santos, R.; Maurer, M.; Zuberbier, T. (2007). "Acquired cold urticaria: clinical picture and update on diagnosis and treatment". Clinical and Experimental Dermatology. 32 (3): 241–245. doi:10.1111/j.1365-2230.2007.02376.x. ISSN 0307-6938.

[KrauseZuberbier2010-4] Krause, Karoline; Zuberbier, Torsten; Maurer, Marcus (2010). "Modern Approaches to the Diagnosis and Treatment of Cold Contact Urticaria". Current Allergy and Asthma Reports. 10 (4): 243–249. doi:10.1007/s11882-010-0121-3. ISSN 1529-7322.

[Kastner2005-5] Kastner, D. L. (2005). "Hereditary Periodic Fever Syndromes". Hematology. 2005 (1): 74–81. doi:10.1182/asheducation-2005.1.74. ISSN 1520-4391.

[de_KoningBodar2007-6] Koning, Heleen D.; Bodar, Evelien J.; van der Meer, Jos W.M.; Simon, Anna (2007). "Schnitzler Syndrome: Beyond the Case Reports: Review and Follow-Up of 94 Patients with an Emphasis on Prognosis and Treatment". Seminars in Arthritis and Rheumatism. 37 (3): 137–148. doi:10.1016/j.semarthrit.2007.04.001. ISSN 0049-0172.

[AksentijevichMasters2009-7] Aksentijevich, Ivona; Masters, Seth L.; Ferguson, Polly J.; Dancey, Paul; Frenkel, Joost; van Royen-Kerkhoff, Annet; Laxer, Ron; Tedgård, Ulf; Cowen, Edward W.; Pham, Tuyet-Hang; Booty, Matthew; Estes, Jacob D.; Sandler, Netanya G.; Plass, Nicole; Stone, Deborah L.; Turner, Maria L.; Hill, Suvimol; Butman, John A.; Schneider, Rayfel; Babyn, Paul; El-Shanti, Hatem I.; Pope, Elena; Barron, Karyl; Bing, Xinyu; Laurence, Arian; Lee, Chyi-Chia R.; Chapelle, Dawn; Clarke, Gillian I.; Ohson, Kamal; Nicholson, Marc; Gadina, Massimo; Yang, Barbara; Korman, Benjamin D.; Gregersen, Peter K.; van Hagen, P. Martin; Hak, A. Elisabeth; Huizing, Marjan; Rahman, Proton; Douek, Daniel C.; Remmers, Elaine F.; Kastner, Daniel L.; Goldbach-Mansky, Raphaela (2009). "An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist". New England Journal of Medicine. 360 (23): 2426–2437. doi:10.1056/NEJMoa0807865. ISSN 0028-4793.

[GurionLehman2012-8] Gurion, R.; Lehman, T. J. A.; Moorthy, L. N. (2012). "Systemic Arthritis in Children: A Review of Clinical Presentation and Treatment". International Journal of Inflammation. 2012: 1–16. doi:10.1155/2012/271569. ISSN 2090-8040.

[Efthimiou2006-9] Efthimiou, P (2006). "Diagnosis and management of adult onset Still's disease". Annals of the Rheumatic Diseases. 65 (5): 564–572. doi:10.1136/ard.2005.042143. ISSN 0003-4967.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Urticaria}}
-{{CMG}}
+{{CMG}}; {{AE}} {{Anahita}}
+==Overview==
+It is critical to differentiate [[urticaria]] from other similar disorders to utilize the best approach for the [[treatment]]. [[Complement deficiency|Hereditary or acquired deficiency of complement factor C1]], cutaneous [[mastocytosis]] such as [[urticaria pigmentosa]], certain [[malignancies]], [[connective tissue diseases]], [[angioedema]] and [[Anaphylaxis causes|exercise‐induced anaphylaxis]] are some of the differential [[diagnosis]] of [[urticaria]].
 ==Differentiating Urticaria from other Diseases==
-* Hereditary or acquired deficiency of compliment factor C1
-* Cutaneous [[mastocytosis]]/urticaria pigmentosa
+*[[Complement deficiency|Hereditary or acquired deficiency of complement factor C1]]
-* [[Malignancy]]
+*[[mast cell tumor|Cutaneous mastocytosis]]/[[urticaria pigmentosa]]
-* Poison ivy contact dermatitis: The rash that develops from poison ivy, poison oak, and poison sumac contact is commonly mistaken for urticaria.  This rash is caused by contact with [[urushiol]] and results in a form of [[contact dermatitis]] called [[Urushiol-induced contact dermatitis]]. Urushiol is spread by contact, but can be washed off with a strong grease/oil dissolving detergent and cool water.
+*[[Malignancy]]
-* [[Angioedema]]: It is related to urticaria.  In angioedema, the swelling occurs in a lower layer of the dermis than it does in urticaria.<ref>{{cite web | url = http://www.webmd.com/allergies/guide/hives-urticaria-angioedema | title = Hives (Urticaria and Angioedema) | date = 2006-03-01 | accessdate = 2007-08-24}}</ref>  This swelling can occur around the mouth, in the throat, in the abdomen, or in other locations.  Urticaria and angioedema sometimes occur together in response to an [[allergen]] and is a concern in severe cases because angioedema of the throat can be fatal.
+*[[Anaphylaxis causes|Exercise‐induced anaphylaxis]]<ref name="pmid14616095">{{cite journal| author=Zuberbier T| title=Urticaria. | journal=Allergy | year= 2003 | volume= 58 | issue= 12 | pages= 1224-34 | pmid=14616095 | doi=10.1046/j.1398-9995.2003.00327.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14616095  }} </ref>
+*[[Connective tissue diseases]]
+*[[Photosensitivity|Photosensitive diseases]]
+*[[Urushiol-induced contact dermatitis|Poison ivy contact dermatitis]]: The [[rash]] that develops from [[Urushiol-induced contact dermatitis|poison ivy, poison oak, and poison sumac contact]] are commonly mistaken for [[urticaria]]. This [[rash]] is caused by contact with [[urushiol]] and results in a form of [[contact dermatitis]] called [[urushiol-induced contact dermatitis]].
+*[[Angioedema]]:
+**Although it might be related to [[urticaria]], [[angioedema]] occurs due to swelling of the lower layers of [[dermis]].<ref>{{cite web | url = http://www.webmd.com/allergies/guide/hives-urticaria-angioedema | title = Hives (Urticaria and Angioedema) | date = 2006-03-01 | accessdate = 2007-08-24}}</ref>
+**[[Edema]] can occur around the [[mouth]], in the [[throat]], in the [[abdomen]], or in other locations. [[Urticaria]] and [[angioedema]] sometimes occur together in response to an [[allergen]] and should be a concern in severe cases because [[angioedema]] of the [[throat]] can be [[fatal]].
+*A possible [[differential diagnosis]] for diseases that cause [[urticaria]], and [[rash]] include:
+**[[Schnitzler syndrome]]
+**[[Deficiency]] in [[Interleukin 1 receptor antagonist|interleukin-1 receptor antagonist]]
+**[[Juvenile idiopathic arthritis]]
+**[[Adult-onset Still's disease]]
+**[[virus|Viral]] [[rashes]]
+*Table below differentiates some of the aforementioned [[conditions]]:
+{| border="3"
+|+
+! style="background: #4479BA; width: 150px;" |{{fontcolor|#FFF| Disease name}}
+! style="background: #4479BA; width: 150px;" |{{fontcolor|#FFF| Age of onset}}
+! style="background: #4479BA; width: 150px;" |{{fontcolor|#FFF| Signs/Symptoms}}
+! style="background: #4479BA; width: 150px;" |{{fontcolor|#FFF|Diagnostic feature(s)}}
+! style="background: #4479BA; width: 150px;" |{{fontcolor|#FFF| Other features}}
+|-
+! style="padding: 5px 5px; background: #DCDCDC; " align="left" |[[urticaria|Cold Contact Urticaria]]<ref name="SiebenhaarWeller2007">{{cite journal|last1=Siebenhaar|first1=F.|last2=Weller|first2=K.|last3=Mlynek|first3=A.|last4=Magerl|first4=M.|last5=Altrichter|first5=S.|last6=Vieira dos Santos|first6=R.|last7=Maurer|first7=M.|last8=Zuberbier|first8=T.|title=Acquired cold urticaria: clinical picture and update on diagnosis and treatment|journal=Clinical and Experimental Dermatology|volume=32|issue=3|year=2007|pages=241–245|issn=0307-6938|doi=10.1111/j.1365-2230.2007.02376.x}}</ref><ref name="KrauseZuberbier2010">{{cite journal|last1=Krause|first1=Karoline|last2=Zuberbier|first2=Torsten|last3=Maurer|first3=Marcus|title=Modern Approaches to the Diagnosis and Treatment of Cold Contact Urticaria|journal=Current Allergy and Asthma Reports|volume=10|issue=4|year=2010|pages=243–249|issn=1529-7322|doi=10.1007/s11882-010-0121-3}}</ref>
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Early adulthood
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*[[Urticaria|Urticarial]] [[skin]] eruption after exposure to cold
+*[[Urticaria]] and/or [[angioedema]] affects areas only in contact with cold
+*Systemic [[symptoms]] may be present in case of extensive [[skin]] involvement (such as [[anaphylaxis]])
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Ice cube test is positive
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*The [[wheal]] appears within 5 minutes of cold contact
+|-
+! style="padding: 5px 5px; background: #DCDCDC; " align="left" |[[Cryopyrin-associated periodic syndrome|Familial Cold Autoinflammatory Syndrome]]<ref name="Kastner2005">{{cite journal|last1=Kastner|first1=D. L.|title=Hereditary Periodic Fever Syndromes|journal=Hematology|volume=2005|issue=1|year=2005|pages=74–81|issn=1520-4391|doi=10.1182/asheducation-2005.1.74}}</ref>
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*[[Infancy]], but may be delayed until adulthood
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Non-[[itch|pruritic]] [[Urticaria|urticarial rash]]
+*[[Fever]]
+*[[Headache]]
+*[[Fatigue]]
+*[[Conjunctivitis]]
+<br />
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Ice cube test is negative
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Cold-induced [[rash]]
+*[[Skin biopsy]] shows increased [[Neutrophil|neutrophils]] at the eccrine coils
+|-
+! style="padding: 5px 5px; background: #DCDCDC; " align="left" |[[Schnitzler syndrome]]<ref name="de KoningBodar2007">{{cite journal|last1=de Koning|first1=Heleen D.|last2=Bodar|first2=Evelien J.|last3=van der Meer|first3=Jos W.M.|last4=Simon|first4=Anna|title=Schnitzler Syndrome: Beyond the Case Reports: Review and Follow-Up of 94 Patients with an Emphasis on Prognosis and Treatment|journal=Seminars in Arthritis and Rheumatism|volume=37|issue=3|year=2007|pages=137–148|issn=00490172|doi=10.1016/j.semarthrit.2007.04.001}}</ref>
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*[[Middle age]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Chronic [[Urticaria|urticarial]] [[rash]]
+*[[Fever]]
+*[[Arthralgia]]
+*[[Bone pain]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*[[Monoclonal gammopathy]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*[[Rash]] is the presenting [[Medical sign|sign]]
+*[[Neutrophil|Neutrophillic]] infiltrate in [[dermis]]
+*[[Dermographism]]
+|-
+! style="padding: 5px 5px; background: #DCDCDC; " align="left" |Deficiency in [[Interleukin 1 receptor antagonist|Interleukin-1 Receptor Antagonist]]<ref name="AksentijevichMasters2009">{{cite journal|last1=Aksentijevich|first1=Ivona|last2=Masters|first2=Seth L.|last3=Ferguson|first3=Polly J.|last4=Dancey|first4=Paul|last5=Frenkel|first5=Joost|last6=van Royen-Kerkhoff|first6=Annet|last7=Laxer|first7=Ron|last8=Tedgård|first8=Ulf|last9=Cowen|first9=Edward W.|last10=Pham|first10=Tuyet-Hang|last11=Booty|first11=Matthew|last12=Estes|first12=Jacob D.|last13=Sandler|first13=Netanya G.|last14=Plass|first14=Nicole|last15=Stone|first15=Deborah L.|last16=Turner|first16=Maria L.|last17=Hill|first17=Suvimol|last18=Butman|first18=John A.|last19=Schneider|first19=Rayfel|last20=Babyn|first20=Paul|last21=El-Shanti|first21=Hatem I.|last22=Pope|first22=Elena|last23=Barron|first23=Karyl|last24=Bing|first24=Xinyu|last25=Laurence|first25=Arian|last26=Lee|first26=Chyi-Chia R.|last27=Chapelle|first27=Dawn|last28=Clarke|first28=Gillian I.|last29=Ohson|first29=Kamal|last30=Nicholson|first30=Marc|last31=Gadina|first31=Massimo|last32=Yang|first32=Barbara|last33=Korman|first33=Benjamin D.|last34=Gregersen|first34=Peter K.|last35=van Hagen|first35=P. Martin|last36=Hak|first36=A. Elisabeth|last37=Huizing|first37=Marjan|last38=Rahman|first38=Proton|last39=Douek|first39=Daniel C.|last40=Remmers|first40=Elaine F.|last41=Kastner|first41=Daniel L.|last42=Goldbach-Mansky|first42=Raphaela|title=An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist|journal=New England Journal of Medicine|volume=360|issue=23|year=2009|pages=2426–2437|issn=0028-4793|doi=10.1056/NEJMoa0807865}}</ref>
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*[[Infancy]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*[[Pustular rash]]
+*[[Bone pain]]
+*Swollen [[joints]]
+*[[Aphthous ulcers]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Occurs due to [[mutation]] in [[Interleukin 1 receptor antagonist|IL1RN]] [[gene]]
+*[[Pustular rash]] similar to [[pustular psoriasis]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*[[Epidermal]] [[Neutrophil|neutrophilic]] [[pustules]] at [[hair follicles]]
+*[[Pathergy test|Pathergy]]
+*[[Hyperkeratosis]] and  acanthosis
+*High [[neutrophil]] infiltrate of the [[dermis]]
+|-
+! style="padding: 5px 5px; background: #DCDCDC; " align="left" |[[Juvenile idiopathic arthritis|Systemic-Onset Juvenile Idiopathic Arthritis]]<ref name="GurionLehman2012">{{cite journal|last1=Gurion|first1=R.|last2=Lehman|first2=T. J. A.|last3=Moorthy|first3=L. N.|title=Systemic Arthritis in Children: A Review of Clinical Presentation and Treatment|journal=International Journal of Inflammation|volume=2012|year=2012|pages=1–16|issn=2090-8040|doi=10.1155/2012/271569}}</ref>
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*2-16 years of age
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*High [[fever]]
+*[[Arthralgia]]
+*[[Generalized lymphadenopathy]]
+*[[Splenomegaly]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Evanescent [[rash]]
+*Bright salmon-pink
+*Morbilliform, [[macular]] [[rash]]
+*[[Rash]] presents with onset of [[fever]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*May cause [[amyloidosis]]
+|-
+! style="padding: 5px 5px; background: #DCDCDC; " align="left" |[[Adult-Onset Still’s Disease]]<ref name="Efthimiou2006">{{cite journal|last1=Efthimiou|first1=P|title=Diagnosis and management of adult onset Still's disease|journal=Annals of the Rheumatic Diseases|volume=65|issue=5|year=2006|pages=564–572|issn=0003-4967|doi=10.1136/ard.2005.042143}}</ref>
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*16-35 years
+*May affect all ages
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*High spiking [[fever]]
+*[[Joint pain]]
+*[[Skin rash]]
+*[[Lymphadenopathy]]
+*[[Splenomegaly]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*Evanescent salmon-colored bumpy [[rash]]
+*[[Itch|Pruritic]] [[rash]] on the [[proximal]] [[Limb (anatomy)|limbs]] and [[trunk]]
+| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+*More commonly seen among women
+*May cause destructive [[arthritis]]
+|}
 ==References==
 {{Reflist|2}}
+{{WH}}
+{{WS}}
 [[Category:Dermatology]]
 [[Category:Allergology]]
@@ Line 18: / Line 139: @@
 [[Category:Emergency medicine]]
 [[Category:Disease]]
-[[Category:Needs overview]]
-[[Category:Primary care]]
-{{WH}}
-{{WS}}

Differentiating urticaria from other diseases: Difference between revisions

Latest revision as of 15:32, 28 January 2021

Overview

Differentiating Urticaria from other Diseases

References

Navigation menu

Search