Hashimoto's thyroiditis history and symptoms: Difference between revisions

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Latest revision as of 21:58, 29 July 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S [2]

Overview

The hallmark of Hashimoto's thyroiditis is hypothyroidism. A positive history of autoimmune diseases and certain drug use are suggestive of Hashimoto's thyroiditis. The most common symptoms of Hashimoto's thyroiditis include fatigue, constipation, and cold intolerance.

History

Patients with Hashimoto's thyroiditis usually have the history of other autoimmune diseases and family history of autoimmune diseases. Occasionally, there might be a history of certain drug use like interferon-alpha and monoclonal antibodies.

Symptoms

In many cases, Hashimoto's thyroiditis usually results in hypothyroidism, although, in its acute phase, it can cause a transient hyperthyroidism thyrotoxic state known as hashitoxicosis. Hypothyroidism resulting from Hashimoto's thyroiditis can cause these symptoms:^[1]^[2]^[3]

Common Symptoms

Organ-based Symptoms

There are several organs involved in the hypothyroidism associated with Hashimoto's thyroiditis. The manifestation of Hashimoto's thyroiditis is variable as a result of the extensive involvement of multiple organs. The organ-based manifestation are as follows:

Location	Symptoms
General	Fatigue Lethargy Cold intolerance Myxedema Weight gain Weight loss Migraines Puffy face
Localized symptoms	Enlarged neck or presence of goiter Dysphonia (from involvement of the recurrent laryngeal nerve) Dyspnea (from the compression of the trachea) Dysphagia (from impingement upon the esophagus) Small or shrunken thyroid gland (late in the disease)
Gastrointestinal system	Constipation
Skin and appendages	Dry skin Hair loss
Neuro-psychiatric system	Depression Difficulty concentrating or thinking Mania Memory loss Panic attacks
Reproductive system	Infertility Oligomenorrhea Menometrorrhagia
Musculoskeletal	Joint stiffness Muscle cramps

References

↑ Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.
↑ Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.
↑ "Hashimoto's Thyroiditis | American Thyroid Association".

Template:WH Template:WS

[1] Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.

[pmid24434360-2] Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.

[urlHashimoto’s_Thyroiditis_|_American_Thyroid_Association-3] "Hashimoto's Thyroiditis | American Thyroid Association".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Hashimoto's thyroiditis}}
-{{CMG}}
+{{CMG}} {{AE}} {{MMF}}
 ==Overview==
+The hallmark of [[Hashimoto's thyroiditis]] is [[hypothyroidism]]. A positive history of [[autoimmune diseases]] and certain drug use are suggestive of Hashimoto's thyroiditis. The most common symptoms of [[Hashimoto's thyroiditis]] include [[fatigue]], [[constipation]], and cold intolerance.
 ==History==
+Patients with [[Hashimoto's thyroiditis]] usually have the history of other [[autoimmune diseases]] and family history of [[autoimmune diseases]]. Occasionally, there might be a history of certain drug use like [[interferon-alpha]] and [[monoclonal antibodies]].
 ==Symptoms==
-In many cases, Hashimoto's thyroiditis usually results in [[hypothyroidism]], although in its acute phase, it can cause a transient hyperthyroidism [[hyperthyroidism|thyrotoxic]] state known as hashitoxicosis.
+In many cases, Hashimoto's thyroiditis usually results in [[hypothyroidism]], although, in its acute phase, it can cause a transient hyperthyroidism [[hyperthyroidism|thyrotoxic]] state known as hashitoxicosis. Hypothyroidism resulting from [[Hashimoto's thyroiditis]] can cause these symptoms:<ref>Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. ''Goldman: Cecil Medicine''. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.</ref><ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref><ref name="urlHashimoto’s Thyroiditis | American Thyroid Association">{{cite web |url=https://www.thyroid.org/hashimotos-thyroiditis/ |title=Hashimoto’s Thyroiditis &#124; American Thyroid Association |format= |work= |accessdate=}}</ref>
+===Common Symptoms===
-* Adolescent goiter
+*[[Fatigue]]
-* Alternating hypo- and hyperthyroidism
+*[[Weight gain]]
-* Euthyroidism and goiter
+*[[Constipation]]
-* Hypothyroidism
+*[[Cold intolerance]]
-* Painless thyroiditis or silent thyroiditis
+*[[Xeroderma|Dry skin]]
-* Postpartum painless thyrotoxicosis
+*[[Depression]]
-* Primary thyroid failure
+*[[Muscle aches]]
-* Subclinical hypothyroidism and goiter
+*Reduced [[Exercise tolerance test|exercise tolerance]]
+*[[Menorrhagia]] or [[metrorrhagia]]
-(In alphabetical order) <ref>Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. ''Goldman: Cecil Medicine''. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.</ref>
+===Organ-based Symptoms===
+There are several organs involved in the [[hypothyroidism]] associated with [[Hashimoto's thyroiditis]]. The manifestation of Hashimoto's thyroiditis is variable as a result of the extensive involvement of multiple organs. The organ-based manifestation are as follows:
+{| class="wikitable"
+!Location
+!Symptoms
+|-
+!General
+|
+* [[Fatigue]]
+* [[Lethargy]]
 * Cold intolerance
+* [[Myxedema]]
+* [[Weight gain]]
+* [[Weight loss]]
+* [[Migraine]]s
+* Puffy face
+|-
+!Localized symptoms
+|
+*Enlarged neck or presence of [[goiter]]
+*[[Dysphonia]] (from involvement of the [[recurrent laryngeal nerve]])
+*[[Dyspnea]] (from the [[Tracheal compression|compression of the trachea]])
+*[[Dysphagia]] (from [[Impingement Syndrome|impingement]] upon the esophagus)
+* Small or shrunken [[thyroid gland]] (late in the disease)
+|-
+!Gastrointestinal system
+|
 * [[Constipation]]
+|-
+!Skin and appendages
+|
+* [[Dry skin]]
+* [[Hair loss]]
+|-
+!Neuro-psychiatric system
+|
 * [[Depression]]
 * Difficulty concentrating or thinking
-* [[Dry skin]]
-* Enlarged neck or presence of [[goiter]]
-* [[Fatigue]]
-* [[Hair loss]]
-* Heavy and irregular periods
-* [[Hyperthyroidism]] symptoms
-* [[Hypothyroidism]] symptoms
-* [[Infertility]]
-* [[Lethargy]]
 * [[Mania]]
 * [[Memory loss]]
-* [[Migraine]]s
-* [[Myxedema]]
 * [[Panic attack]]s
-* Puffy face
+|-
-* Small or shrunken thyroid gland (late in the disease)
+!Reproductive system
-* [[Weight gain]]
+|
-* [[Weight loss]]
+* [[Infertility]]
+*[[Oligomenorrhea]]
-Other symptoms that can occur with this disease:
+*[[Menometrorrhagia]]
+|-
-* Joint stiffness
+!Musculoskeletal
-* Swelling of the face
+|
+*[[Joint stiffness]]
+*[[Muscle cramps]]
+|}
 ==References==
@@ Line 55: / Line 79: @@
 {{WH}}
 {{WS}}
-[[Category:Needs content]]
+[[Category:Medicine]]
 [[Category:Endocrinology]]
+[[Category:Up-To-Date]]