Cholesterolosis of gallbladder pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
* Gallbladder [[cholecystoses]] are conditions characterized by the accumulation of [[cholesterol]] and other fats in the gallbladder. The two main forms are [[adenomyomatosis]] and [[cholesterolosis]]. | |||
* [[Cholesterolosis]] of gallbladder develops from deposition of [[triglycerides]] and [[cholesterol esters]] within the [[lamina propria]] of gallbladder wall causing [[mucosal]] [[hyperplasia]]. | |||
* Deposition of cholesterol [[esters]] can be diffused or localized. | |||
* Gross appearance of the [[mucosa]] of gallbladder wall due to diffuse cholesterolosis is known as "strawberry gallbladder". | |||
* Cholesterolosis should be differentiated from [[adenomyomatosis]] which involves hyperplasia of both mucosa and [[muscularis propria]].<ref name="pmid16702464">{{cite journal |vauthors=Boscak AR, Al-Hawary M, Ramsburgh SR |title=Best cases from the AFIP: Adenomyomatosis of the gallbladder |journal=Radiographics |volume=26 |issue=3 |pages=941–6 |date=2006 |pmid=16702464 |doi=10.1148/rg.263055180 |url=}}</ref> | |||
==References== | ==References== | ||
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[[Category:Surgery]] | [[Category:Surgery]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Hepatology]] | |||
{{WS}} | {{WS}} | ||
{{WH}} | {{WH}} | ||
Latest revision as of 04:57, 8 November 2020
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Overview
Pathophysiology
- Gallbladder cholecystoses are conditions characterized by the accumulation of cholesterol and other fats in the gallbladder. The two main forms are adenomyomatosis and cholesterolosis.
- Cholesterolosis of gallbladder develops from deposition of triglycerides and cholesterol esters within the lamina propria of gallbladder wall causing mucosal hyperplasia.
- Deposition of cholesterol esters can be diffused or localized.
- Gross appearance of the mucosa of gallbladder wall due to diffuse cholesterolosis is known as "strawberry gallbladder".
- Cholesterolosis should be differentiated from adenomyomatosis which involves hyperplasia of both mucosa and muscularis propria.[1]
References
- ↑ Boscak AR, Al-Hawary M, Ramsburgh SR (2006). "Best cases from the AFIP: Adenomyomatosis of the gallbladder". Radiographics. 26 (3): 941–6. doi:10.1148/rg.263055180. PMID 16702464.