Differentiating Metabolic syndrome from other diseases: Difference between revisions

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__NOTOC__
__NOTOC__
{{Metabolic syndrome}}
[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Metabolic_syndrome]]
{{CMG}}
{{CMG}}; {{AE}} {{MMF}}


==Overview==
==Overview==
Metabolic syndrome syndrome must be differentiated from other diseases that cause [[hypertension]], [[obesity]], and [[hyperandrogenism]], such as [[Cushing's syndrome]] and [[pseudo-Cushing's syndrome]].
==Differentiating Metabolic Syndrome from other Diseases==
The table below summarizes the findings that differentiate pseudo-Cushing's disease from other conditions that may cause [[Hypertension|hypertension]]<nowiki/>, [[hyperandrogenism]], [[obesity]], [[Facial|facial plethora]], skin changes, [[osteoporosis]], [[nephrolithiasis]] and [[neuropsychiatric]] conditions.<ref name="pmid11253984">{{cite journal |vauthors=Boscaro M, Barzon L, Fallo F, Sonino N |title=Cushing's syndrome |journal=Lancet |volume=357 |issue=9258 |pages=783–91 |year=2001 |pmid=11253984 |doi=10.1016/S0140-6736(00)04172-6 |url=}}</ref><ref name="pmid11571938">{{cite journal |vauthors=Findling JW, Raff H |title=Diagnosis and differential diagnosis of Cushing's syndrome |journal=Endocrinol. Metab. Clin. North Am. |volume=30 |issue=3 |pages=729–47 |year=2001 |pmid=11571938 |doi= |url=}}</ref><ref name="pmid9793762">{{cite journal |vauthors=Newell-Price J, Trainer P, Besser M, Grossman A |title=The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states |journal=Endocr. Rev. |volume=19 |issue=5 |pages=647–72 |year=1998 |pmid=9793762 |doi=10.1210/edrv.19.5.0346 |url=}}</ref><ref name="urlHow Is Metabolic Syndrome Diagnosed? - NHLBI, NIH">{{cite web |url=https://www.nhlbi.nih.gov/health/health-topics/topics/ms/diagnosis |title=How Is Metabolic Syndrome Diagnosed? - NHLBI, NIH |format= |work= |accessdate=}}</ref>
<br>
{| align="center"
|-
|
{| align="center" style="border: 0px; font-size: 90%; margin: 3px;"
! style="background:#4479BA; color: #FFFFFF;" | Conditions
! style="background:#4479BA; color: #FFFFFF;" |Causes
! style="background:#4479BA; color: #FFFFFF;" |Associated features
! style="background:#4479BA; color: #FFFFFF;" |Diagnostic approach   
|-
| align="center" style="background:#DCDCDC;" |[[Metabolic syndrome X]]
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
*[[Genetics|Familial/genetic]]
*[[Obesity]]
*[[Insulin]] resistance
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
* [[Obesity]]
*[[Hypertension]]
*[[PCOS]]/[[hyperandrogenism]]
*[[Oligomenorrhea]]/[[hypogonadism]]
*[[Dyslipidemia]]
*[[Diabetes mellitus|Diabetes]]/[[Glucose intolerance]]
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
*Waist circumference
*[[Lipoproteins|Low-density lipoproteins]]
*[[Lipoproteins|High-density lipoproteins]]
*[[Glucose tolerance test]]
*[[Fasting blood sugar]]
*[[HbA1c]]
|-
| align="center" style="background:#DCDCDC;" |[[Cushing's syndrome]]
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
*Iatrogenic
*[[Pituitary adenoma]]
*[[Adrenal tumor]]
*[[Adrenal hyperplasia]]
*Ectopic [[ACTH]] secretion
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
* [[Obesity]]
*[[Hypertension]]
*[[PCOS]]/[[hyperandrogenism]]
*[[Oligomenorrhea]]/[[hypogonadism]]
*[[Osteoporosis]]
*[[Myopathy]]/cutaneous wasting
*Neuropsychiatric problems
*[[Kidney stone|Kidney stones]]
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
*24-hour urine [[cortisol]]
*Midnight salivary [[cortisol]]
*Low dose [[dexamethasone]] challenge test
*[[CRH]] stimulation
*High dose [[dexamethasone]] test
*[[MRI]] brain
*[[CT]]/[[MRI]] [[Adrenal|adrenals]]


==Differentiating Metabolic Syndrome from other Diseases==
|-
| align="center" style="background:#DCDCDC;" |[[Pseudo-Cushing's syndrome]]
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
*[[Obesity]]
*[[Alcoholism]]
*[[Depression]]
*[[HIV]]
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
* [[Obesity]]
*[[Hypertension]]
*[[PCOS]]/[[hyperandrogenism]]
*[[Oligomenorrhea]]/[[hypogonadism]]
| align="left" style="padding: 5px 5px; background: #F5F5F5;" |
*Urinary free [[cortisol]]
*Midnight salivary [[cortisol]]
*Low dose [[dexamethasone]] challenge test
*[[Glucose tolerance test]]
*[[Loperamide]] test
|}


==References==
==References==
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[[Category:Needs content]]
[[Category:Needs overview]]
[[Category:Needs overview]]
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Latest revision as of 22:38, 25 February 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

Metabolic syndrome syndrome must be differentiated from other diseases that cause hypertension, obesity, and hyperandrogenism, such as Cushing's syndrome and pseudo-Cushing's syndrome.

Differentiating Metabolic Syndrome from other Diseases

The table below summarizes the findings that differentiate pseudo-Cushing's disease from other conditions that may cause hypertension, hyperandrogenism, obesity, facial plethora, skin changes, osteoporosis, nephrolithiasis and neuropsychiatric conditions.[1][2][3][4]

Conditions Causes Associated features Diagnostic approach
Metabolic syndrome X
Cushing's syndrome
Pseudo-Cushing's syndrome

References

  1. ↑ Boscaro M, Barzon L, Fallo F, Sonino N (2001). "Cushing's syndrome". Lancet. 357 (9258): 783–91. doi:10.1016/S0140-6736(00)04172-6. PMID 11253984.
  2. ↑ Findling JW, Raff H (2001). "Diagnosis and differential diagnosis of Cushing's syndrome". Endocrinol. Metab. Clin. North Am. 30 (3): 729–47. PMID 11571938.
  3. ↑ Newell-Price J, Trainer P, Besser M, Grossman A (1998). "The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states". Endocr. Rev. 19 (5): 647–72. doi:10.1210/edrv.19.5.0346. PMID 9793762.
  4. ↑ "How Is Metabolic Syndrome Diagnosed? - NHLBI, NIH".

Template:WS Template:WH

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