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==Overview==
==Overview==
If left untreated, patients with lactose intoelrance may progress to develop [[malnutrition]], [[osteomalacia]], and [[osteopenia]]. Common complications of lactose intoelrance include include [[Osteoporosis|osteoprosis]], [[osteopenia]], [[osteomalacia]] (especially in the absence of calcium supplements) and [[malnutrition]]. Prognosis is generally excellent.
==Natural History, Complications, and Prognosis==


==Natural History==
===Natural History===
*The [[Symptom|symptoms]] of lactose intoelrance usually develop after age of 6 and start with:<ref name="pmid25855879">{{cite journal |vauthors=Szilagyi A |title=Adult lactose digestion status and effects on disease |journal=Can J Gastroenterol Hepatol |volume=29 |issue=3 |pages=149–56 |year=2015 |pmid=25855879 |pmc=4399375 |doi= |url=}}</ref><ref name="pmid7776987">{{cite journal |vauthors=Suarez FL, Savaiano DA, Levitt MD |title=A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance |journal=N. Engl. J. Med. |volume=333 |issue=1 |pages=1–4 |year=1995 |pmid=7776987 |doi=10.1056/NEJM199507063330101 |url=}}</ref><ref name="pmid22826639">{{cite journal |vauthors=Mattar R, de Campos Mazo DF, Carrilho FJ |title=Lactose intolerance: diagnosis, genetic, and clinical factors |journal=Clin Exp Gastroenterol |volume=5 |issue= |pages=113–21 |year=2012 |pmid=22826639 |pmc=3401057 |doi=10.2147/CEG.S32368 |url=}}</ref>
**[[Abdominal pain]]
**[[Flatulence]]
**[[Bloating]]
**Watery, frothy and bulky [[diarrhea]]
*If left untreated, patients with lactose intolerance may develop:
**[[Malnutrition]]
**[[Osteomalacia]]
**[[Osteopenia]]


==Complications==
===Complications===
*Common complications of lactose intolerance i(especially in the absence of calcium supplements) include: <ref name="pmid228266392">{{cite journal |vauthors=Mattar R, de Campos Mazo DF, Carrilho FJ |title=Lactose intolerance: diagnosis, genetic, and clinical factors |journal=Clin Exp Gastroenterol |volume=5 |issue= |pages=113–21 |year=2012 |pmid=22826639 |pmc=3401057 |doi=10.2147/CEG.S32368 |url=}}</ref><ref name="pmid264043642">{{cite journal |vauthors=Silanikove N, Leitner G, Merin U |title=The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds |journal=Nutrients |volume=7 |issue=9 |pages=7312–31 |year=2015 |pmid=26404364 |pmc=4586535 |doi=10.3390/nu7095340 |url=}}</ref><ref name="pmid27882862">{{cite journal |vauthors=Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A |title=Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence |journal=Food Nutr Res |volume=60 |issue= |pages=32527 |year=2016 |pmid=27882862 |pmc=5122229 |doi= |url=}}</ref>
**[[Osteopenia]]
**[[Osteoporosis]]
**[[Malnutrition]]
**[[Rickets]]
**[[Osteomalacia]]


==Prognosis==
===Prognosis===
Lactose intolerance is common, it is not a threat to good [[health]].
*Prognosis is generally excellent.


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:Endocrinology]]
[[Category:Medicine]]
[[Category:Needs content]]
[[Category:Up-To-Date]]
[[Category:Needs overview]]

Latest revision as of 22:28, 29 July 2020

Lactose Intolerance Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]

Overview

If left untreated, patients with lactose intoelrance may progress to develop malnutrition, osteomalacia, and osteopenia. Common complications of lactose intoelrance include include osteoprosis, osteopenia, osteomalacia (especially in the absence of calcium supplements) and malnutrition. Prognosis is generally excellent.

Natural History, Complications, and Prognosis

Natural History

Complications

Prognosis

  • Prognosis is generally excellent.

References

  1. Szilagyi A (2015). "Adult lactose digestion status and effects on disease". Can J Gastroenterol Hepatol. 29 (3): 149–56. PMC 4399375. PMID 25855879.
  2. Suarez FL, Savaiano DA, Levitt MD (1995). "A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance". N. Engl. J. Med. 333 (1): 1–4. doi:10.1056/NEJM199507063330101. PMID 7776987.
  3. Mattar R, de Campos Mazo DF, Carrilho FJ (2012). "Lactose intolerance: diagnosis, genetic, and clinical factors". Clin Exp Gastroenterol. 5: 113–21. doi:10.2147/CEG.S32368. PMC 3401057. PMID 22826639.
  4. Mattar R, de Campos Mazo DF, Carrilho FJ (2012). "Lactose intolerance: diagnosis, genetic, and clinical factors". Clin Exp Gastroenterol. 5: 113–21. doi:10.2147/CEG.S32368. PMC 3401057. PMID 22826639.
  5. Silanikove N, Leitner G, Merin U (2015). "The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds". Nutrients. 7 (9): 7312–31. doi:10.3390/nu7095340. PMC 4586535. PMID 26404364.
  6. Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A (2016). "Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence". Food Nutr Res. 60: 32527. PMC 5122229. PMID 27882862.

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