Blepharitis differential diagnosis: Difference between revisions

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==Overview==
==Overview==
Blepharitis must be differentiated from other diseases that cause eye itching, irritation, burning, and foreign body sensation such as [[allergic contact dermatitis]], [[conjunctivitis]], [[trichiasis]], [[dry eye syndrome]], [[keratitis]], [[hordeolum]], [[chalazion]], [[rosacea]], and [[sebaceous|sebaceous carcinoma]].<ref name="pmid15534133">{{cite journal| author=Mathers WD, Choi D| title=Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye. | journal=Arch Ophthalmol | year= 2004 | volume= 122 | issue= 11 | pages= 1700-4 | pmid=15534133 | doi=10.1001/archopht.122.11.1700 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15534133  }} </ref>
Blepharitis must be differentiated from other diseases that cause eye itching, irritation, burning, and foreign body sensation such as [[allergic contact dermatitis]], [[conjunctivitis]], [[trichiasis]], [[dry eye syndrome]], [[keratitis]], [[hordeolum]], [[chalazion]], [[rosacea]], and [[sebaceous|sebaceous carcinoma]].


==Differentiating Blepharitis from Other Diseases==
==Differentiating Blepharitis from Other Diseases==
Blepharitis must be differentiated from other diseases that cause red, swollen, and itchy eyes.
Blepharitis must be differentiated from other conditions associated with eyelid inflammation, including:<ref>“Blepharitis - Preferred Practice Pattern Guideline - 2013 - American Academy of Ophthalmology.” http://www.aao.org/preferred-practice-pattern/blepharitis-ppp--2013.</ref>
Blepharitis must be differentiated from:<ref name="pmid15534133">{{cite journal| author=Mathers WD, Choi D| title=Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye. | journal=Arch Ophthalmol | year= 2004 | volume= 122 | issue= 11 | pages= 1700-4 | pmid=15534133 | doi=10.1001/archopht.122.11.1700 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15534133  }} </ref><ref name="pmid19383269">{{cite journal| author=Lemp MA, Nichols KK| title=Blepharitis in the United States 2009: a survey-based perspective on prevalence and treatment. | journal=Ocul Surf | year= 2009 | volume= 7 | issue= 2 Suppl | pages= S1-S14 | pmid=19383269 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19383269  }} </ref><ref name="pmid4236660">{{cite journal| author=Beare JM| title=Blepharitis and related conditions. | journal=Proc R Soc Med | year= 1969 | volume= 62 | issue= 1 | pages= 5-7 | pmid=4236660 | doi= | pmc=2279072 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4236660  }} </ref><ref name="pmid3818198">{{cite journal| author=Bowman RW, Dougherty JM, McCulley JP| title=Chronic blepharitis and dry eyes. | journal=Int Ophthalmol Clin | year= 1987 | volume= 27 | issue= 1 | pages= 27-35 | pmid=3818198 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3818198  }} </ref><ref name=Blepharitis-1> Blepharitis. American Academy of Ophthalmology/eyewiki (2014) http://eyewiki.org/Blepharitis Accessed on July 14, 2016 </ref><ref name="pmid10922425">{{cite journal| author=Leibowitz HM| title=The red eye. | journal=N Engl J Med | year= 2000 | volume= 343 | issue= 5 | pages= 345-51 | pmid=10922425 | doi=10.1056/NEJM200008033430507 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10922425  }} </ref>
 
{| class="wikitable" style = "width: 900px"
|-
! colspan="2" style="text-align: center;" | '''Differential diagnosis of blepharitis'''
|-
| '''Condition'''
| '''Entity'''
|-
| Bacterial infections
|
* [[Impetigo]] (due primarily to ''Staphylococcus aureas'')
* [[Erysipelas]] (due primarily to ''Streptococcus pyogenes'')
|-
| Viral infections
|
* [[Herpes simplex virus]]
* [[Molluscum contagiosum]]
* [[Varicella zoster virus]]
* [[Papillomavirus]]
* [[Vaccinia]]
|-
| Parasitic infections
|
* Pediculosis palpebrarum (Phthirus pubis)
|-
| Immunologic conditions
|
* [[Atopic dermatitis]]
* [[Contact dermatitis]]
* [[Erythema multiforme]]
* [[Pemphigus foliaceus]]
* Ocular mucous membrane [[pemphigoid]] (OMMP)
* [[Stevens-Johnson syndrome]]
* [[Discoid lupus]]
* [[Dermatomyositis]]
* [[Graft-versus-host disease]] (GVHD)
* [[Crohn disease]]
|-
| Dermatoses
|
* [[Psoriasis]]
* [[Ichthyosis]]
* [[Exfoliative dermatitis]]
* [[Erythroderma]]
|-
| Benign eyelid tumors
|
* Pseudoepitheliomatous hyperplasia
* [[Actinic keratosis]]
* [[Squamous cell papilloma]]
* [[Sebaceous gland]] [[hyperplasia]]
* [[Hemangioma]]
* [[Pyogenic granuloma]]
|-
| Malignant eyelid tumors
|
* [[Basal cell carcinoma]]
* [[Squamous cell carcinoma]]
* Sebaceous carcinoma
* [[Melanoma]]
* [[Kaposi sarcoma]]
* [[Mycosis fungoides]]
|-
| Trauma
|
* Chemical
* Thermal
* Radiation
* Mechanical
* Surgical
|-
| Toxic conditions
|
* Medicamentosa
|-
|}
 
Blepharitis must be differentiated from other diseases that cause red, swollen, and itchy eyes, including:<ref name="pmid15534133">{{cite journal| author=Mathers WD, Choi D| title=Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye. | journal=Arch Ophthalmol | year= 2004 | volume= 122 | issue= 11 | pages= 1700-4 | pmid=15534133 | doi=10.1001/archopht.122.11.1700 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15534133  }} </ref><ref name="pmid19383269">{{cite journal| author=Lemp MA, Nichols KK| title=Blepharitis in the United States 2009: a survey-based perspective on prevalence and treatment. | journal=Ocul Surf | year= 2009 | volume= 7 | issue= 2 Suppl | pages= S1-S14 | pmid=19383269 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19383269  }} </ref><ref name="pmid4236660">{{cite journal| author=Beare JM| title=Blepharitis and related conditions. | journal=Proc R Soc Med | year= 1969 | volume= 62 | issue= 1 | pages= 5-7 | pmid=4236660 | doi= | pmc=2279072 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4236660  }} </ref><ref name="pmid3818198">{{cite journal| author=Bowman RW, Dougherty JM, McCulley JP| title=Chronic blepharitis and dry eyes. | journal=Int Ophthalmol Clin | year= 1987 | volume= 27 | issue= 1 | pages= 27-35 | pmid=3818198 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3818198  }} </ref><ref name=Blepharitis-1> Blepharitis. American Academy of Ophthalmology/eyewiki (2014) http://eyewiki.org/Blepharitis Accessed on July 14, 2016 </ref><ref name="pmid10922425">{{cite journal| author=Leibowitz HM| title=The red eye. | journal=N Engl J Med | year= 2000 | volume= 343 | issue= 5 | pages= 345-51 | pmid=10922425 | doi=10.1056/NEJM200008033430507 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10922425  }} </ref>
*[[Allergic contact dermatitis]]
*[[Allergic contact dermatitis]]
*[[Allergic conjunctivitis]] (atopic keratoconjunctivitis)
*[[Allergic conjunctivitis]] (atopic keratoconjunctivitis)
Line 21: Line 98:
*[[Superior limbic keratoconjunctivitis]]
*[[Superior limbic keratoconjunctivitis]]
*[[Contact lens|Contact lens complications]]
*[[Contact lens|Contact lens complications]]
*[[Sebaceous|Sebaceous carcinoma]]  
*[[Sebaceous|Sebaceous carcinoma]]


==References==
==References==
{{reflist|2}}
{{reflist|2}}


[[Category:Infectious disease]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Ophthalmology]]
[[Category:Ophthalmology]]
[[Category:Immunology]]
[[Category:Primary care]]
[[Category:FinalQCRequired]]
{{WH}}
{{WS}}

Latest revision as of 20:38, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]

Overview

Blepharitis must be differentiated from other diseases that cause eye itching, irritation, burning, and foreign body sensation such as allergic contact dermatitis, conjunctivitis, trichiasis, dry eye syndrome, keratitis, hordeolum, chalazion, rosacea, and sebaceous carcinoma.

Differentiating Blepharitis from Other Diseases

Blepharitis must be differentiated from other conditions associated with eyelid inflammation, including:[1]

Differential diagnosis of blepharitis
Condition Entity
Bacterial infections
  • Impetigo (due primarily to Staphylococcus aureas)
  • Erysipelas (due primarily to Streptococcus pyogenes)
Viral infections
Parasitic infections
  • Pediculosis palpebrarum (Phthirus pubis)
Immunologic conditions
Dermatoses
Benign eyelid tumors
Malignant eyelid tumors
Trauma
  • Chemical
  • Thermal
  • Radiation
  • Mechanical
  • Surgical
Toxic conditions
  • Medicamentosa

Blepharitis must be differentiated from other diseases that cause red, swollen, and itchy eyes, including:[2][3][4][5][6][7]

References

  1. ↑ “Blepharitis - Preferred Practice Pattern Guideline - 2013 - American Academy of Ophthalmology.” http://www.aao.org/preferred-practice-pattern/blepharitis-ppp--2013.
  2. ↑ Mathers WD, Choi D (2004). "Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye". Arch Ophthalmol. 122 (11): 1700–4. doi:10.1001/archopht.122.11.1700. PMID 15534133.
  3. ↑ Lemp MA, Nichols KK (2009). "Blepharitis in the United States 2009: a survey-based perspective on prevalence and treatment". Ocul Surf. 7 (2 Suppl): S1–S14. PMID 19383269.
  4. ↑ Beare JM (1969). "Blepharitis and related conditions". Proc R Soc Med. 62 (1): 5–7. PMC 2279072. PMID 4236660.
  5. ↑ Bowman RW, Dougherty JM, McCulley JP (1987). "Chronic blepharitis and dry eyes". Int Ophthalmol Clin. 27 (1): 27–35. PMID 3818198.
  6. ↑ Blepharitis. American Academy of Ophthalmology/eyewiki (2014) http://eyewiki.org/Blepharitis Accessed on July 14, 2016
  7. ↑ Leibowitz HM (2000). "The red eye". N Engl J Med. 343 (5): 345–51. doi:10.1056/NEJM200008033430507. PMID 10922425.
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