Blepharitis differential diagnosis: Difference between revisions

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==Overview==
==Overview==
Blepharitis must be differentiated from other diseases that cause eye itching, irritation, burning, and foreign body sensation such as [[allergic contact dermatitis]], [[conjunctivitis]], [[trichiasis]], [[dry eye syndrome]], [[keratitis]], [[hordeolum]], [[chalazion]], [[rosacea]], and [[sebaceous|sebaceous carcinoma]].<ref name="pmid15534133">{{cite journal| author=Mathers WD, Choi D| title=Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye. | journal=Arch Ophthalmol | year= 2004 | volume= 122 | issue= 11 | pages= 1700-4 | pmid=15534133 | doi=10.1001/archopht.122.11.1700 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15534133  }} </ref>
Blepharitis must be differentiated from other diseases that cause eye itching, irritation, burning, and foreign body sensation such as [[allergic contact dermatitis]], [[conjunctivitis]], [[trichiasis]], [[dry eye syndrome]], [[keratitis]], [[hordeolum]], [[chalazion]], [[rosacea]], and [[sebaceous|sebaceous carcinoma]].


==Differentiating Blepharitis from Other Diseases==
==Differentiating Blepharitis from Other Diseases==
Blepharitis must be differentiated from other diseases that cause red, swollen, and itchy eyes.
Blepharitis must be differentiated from other conditions associated with eyelid inflammation, including:<ref>“Blepharitis - Preferred Practice Pattern Guideline - 2013 - American Academy of Ophthalmology.” http://www.aao.org/preferred-practice-pattern/blepharitis-ppp--2013.</ref>
Blepharitis must be differentiated from:<ref name="pmid15534133">{{cite journal| author=Mathers WD, Choi D| title=Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye. | journal=Arch Ophthalmol | year= 2004 | volume= 122 | issue= 11 | pages= 1700-4 | pmid=15534133 | doi=10.1001/archopht.122.11.1700 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15534133  }} </ref><ref name="pmid19383269">{{cite journal| author=Lemp MA, Nichols KK| title=Blepharitis in the United States 2009: a survey-based perspective on prevalence and treatment. | journal=Ocul Surf | year= 2009 | volume= 7 | issue= 2 Suppl | pages= S1-S14 | pmid=19383269 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19383269  }} </ref><ref name="pmid4236660">{{cite journal| author=Beare JM| title=Blepharitis and related conditions. | journal=Proc R Soc Med | year= 1969 | volume= 62 | issue= 1 | pages= 5-7 | pmid=4236660 | doi= | pmc=2279072 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4236660  }} </ref><ref name="pmid3818198">{{cite journal| author=Bowman RW, Dougherty JM, McCulley JP| title=Chronic blepharitis and dry eyes. | journal=Int Ophthalmol Clin | year= 1987 | volume= 27 | issue= 1 | pages= 27-35 | pmid=3818198 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3818198  }} </ref><ref name=Blepharitis-1> Blepharitis. American Academy of Ophthalmology/eyewiki (2014) http://eyewiki.org/Blepharitis Accessed on July 14, 2016 </ref><ref name="pmid10922425">{{cite journal| author=Leibowitz HM| title=The red eye. | journal=N Engl J Med | year= 2000 | volume= 343 | issue= 5 | pages= 345-51 | pmid=10922425 | doi=10.1056/NEJM200008033430507 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10922425  }} </ref>
*[[Allergic contact dermatitis]]
*[[Allergic conjunctivitis]] (atopic keratoconjunctivitis)
*[[Bacterial conjunctivitis]]
*[[Viral conjunctivitis]]
*[[Trichiasis]]
*[[Dry eye syndrome]]
*[[Keratitis]]
*[[Hordeolum]]
*[[Chalazion]]
*[[Rosacea]]
*[[Superior limbic keratoconjunctivitis]]
*[[Contact lens|Contact lens complications]]
*[[Sebaceous|Sebaceous carcinoma]]
 
 
<ref>“Blepharitis PPP - 2013 - American Academy of Ophthalmology.” Accessed August 1, 2016. http://www.aao.org/preferred-practice-pattern/blepharitis-ppp--2013.</ref>


{| class="wikitable" style = "width: 900px"
{| class="wikitable" style = "width: 900px"
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| Bacterial infections
| Bacterial infections
|
|
* Impetigo (due primarily to Staphylococcus aureas)
* [[Impetigo]] (due primarily to ''Staphylococcus aureas'')
* Erysipelas (due primarily to Streptococcus pyogenes)
* [[Erysipelas]] (due primarily to ''Streptococcus pyogenes'')
|-
|-
| Viral infections
| Viral infections
|
|
* Herpes simplex virus
* [[Herpes simplex virus]]
* Molluscum contagiosum
* [[Molluscum contagiosum]]
* Varicella zoster virus
* [[Varicella zoster virus]]
* Papillomavirus
* [[Papillomavirus]]
* Vaccinia
* [[Vaccinia]]
|-
|-
| Parasitic infections
| Parasitic infections
Line 52: Line 35:
| Immunologic conditions
| Immunologic conditions
|
|
* Atopic dermatitis
* [[Atopic dermatitis]]
* Contact dermatitis
* [[Contact dermatitis]]
* Erythema multiforme
* [[Erythema multiforme]]
* Pemphigus foliaceus
* [[Pemphigus foliaceus]]
* Ocular mucous membrane pemphigoid (OMMP)
* Ocular mucous membrane [[pemphigoid]] (OMMP)
* Stevens-Johnson syndrome
* [[Stevens-Johnson syndrome]]
* Discoid lupus
* [[Discoid lupus]]
* Dermatomyositis
* [[Dermatomyositis]]
* Graft-versus-host disease (GVHD)
* [[Graft-versus-host disease]] (GVHD)
* Crohn disease
* [[Crohn disease]]
|-
|-
| Dermatoses
| Dermatoses
|
|
* Psoriasis
* [[Psoriasis]]
* Ichthyosis
* [[Ichthyosis]]
* Exfoliative dermatitis
* [[Exfoliative dermatitis]]
* Erythroderma
* [[Erythroderma]]
|-
|-
| Benign eyelid tumors
| Benign eyelid tumors
|
|
* Pseudoepitheliomatous hyperplasia
* Pseudoepitheliomatous hyperplasia
* Actinic keratosis
* [[Actinic keratosis]]
* Squamous cell papilloma
* [[Squamous cell papilloma]]
* Sebaceous gland hyperplasia
* [[Sebaceous gland]] [[hyperplasia]]
* Hemangioma
* [[Hemangioma]]
* Pyogenic granuloma
* [[Pyogenic granuloma]]
|-
|-
| Malignant eyelid tumors
| Malignant eyelid tumors
|
|
* Basal cell carcinoma
* [[Basal cell carcinoma]]
* Squamous cell carcinoma
* [[Squamous cell carcinoma]]
* Sebaceous carcinoma
* Sebaceous carcinoma
* Melanoma
* [[Melanoma]]
* Kaposi sarcoma
* [[Kaposi sarcoma]]
* Mycosis fungoides
* [[Mycosis fungoides]]
|-
|-
| Trauma
| Trauma
Line 101: Line 84:
|-
|-
|}
|}
Blepharitis must be differentiated from other diseases that cause red, swollen, and itchy eyes, including:<ref name="pmid15534133">{{cite journal| author=Mathers WD, Choi D| title=Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye. | journal=Arch Ophthalmol | year= 2004 | volume= 122 | issue= 11 | pages= 1700-4 | pmid=15534133 | doi=10.1001/archopht.122.11.1700 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15534133  }} </ref><ref name="pmid19383269">{{cite journal| author=Lemp MA, Nichols KK| title=Blepharitis in the United States 2009: a survey-based perspective on prevalence and treatment. | journal=Ocul Surf | year= 2009 | volume= 7 | issue= 2 Suppl | pages= S1-S14 | pmid=19383269 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19383269  }} </ref><ref name="pmid4236660">{{cite journal| author=Beare JM| title=Blepharitis and related conditions. | journal=Proc R Soc Med | year= 1969 | volume= 62 | issue= 1 | pages= 5-7 | pmid=4236660 | doi= | pmc=2279072 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4236660  }} </ref><ref name="pmid3818198">{{cite journal| author=Bowman RW, Dougherty JM, McCulley JP| title=Chronic blepharitis and dry eyes. | journal=Int Ophthalmol Clin | year= 1987 | volume= 27 | issue= 1 | pages= 27-35 | pmid=3818198 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3818198  }} </ref><ref name=Blepharitis-1> Blepharitis. American Academy of Ophthalmology/eyewiki (2014) http://eyewiki.org/Blepharitis Accessed on July 14, 2016 </ref><ref name="pmid10922425">{{cite journal| author=Leibowitz HM| title=The red eye. | journal=N Engl J Med | year= 2000 | volume= 343 | issue= 5 | pages= 345-51 | pmid=10922425 | doi=10.1056/NEJM200008033430507 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10922425  }} </ref>
*[[Allergic contact dermatitis]]
*[[Allergic conjunctivitis]] (atopic keratoconjunctivitis)
*[[Bacterial conjunctivitis]]
*[[Viral conjunctivitis]]
*[[Trichiasis]]
*[[Dry eye syndrome]]
*[[Keratitis]]
*[[Hordeolum]]
*[[Chalazion]]
*[[Rosacea]]
*[[Superior limbic keratoconjunctivitis]]
*[[Contact lens|Contact lens complications]]
*[[Sebaceous|Sebaceous carcinoma]]


==References==
==References==
{{reflist|2}}
{{reflist|2}}


[[Category:Infectious disease]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Ophthalmology]]
[[Category:Ophthalmology]]
[[Category:Immunology]]
[[Category:Primary care]]
[[Category:FinalQCRequired]]
{{WH}}
{{WS}}

Latest revision as of 20:38, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]

Overview

Blepharitis must be differentiated from other diseases that cause eye itching, irritation, burning, and foreign body sensation such as allergic contact dermatitis, conjunctivitis, trichiasis, dry eye syndrome, keratitis, hordeolum, chalazion, rosacea, and sebaceous carcinoma.

Differentiating Blepharitis from Other Diseases

Blepharitis must be differentiated from other conditions associated with eyelid inflammation, including:[1]

Differential diagnosis of blepharitis
Condition Entity
Bacterial infections
  • Impetigo (due primarily to Staphylococcus aureas)
  • Erysipelas (due primarily to Streptococcus pyogenes)
Viral infections
Parasitic infections
  • Pediculosis palpebrarum (Phthirus pubis)
Immunologic conditions
Dermatoses
Benign eyelid tumors
Malignant eyelid tumors
Trauma
  • Chemical
  • Thermal
  • Radiation
  • Mechanical
  • Surgical
Toxic conditions
  • Medicamentosa

Blepharitis must be differentiated from other diseases that cause red, swollen, and itchy eyes, including:[2][3][4][5][6][7]

References

  1. ↑ “Blepharitis - Preferred Practice Pattern Guideline - 2013 - American Academy of Ophthalmology.” http://www.aao.org/preferred-practice-pattern/blepharitis-ppp--2013.
  2. ↑ Mathers WD, Choi D (2004). "Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye". Arch Ophthalmol. 122 (11): 1700–4. doi:10.1001/archopht.122.11.1700. PMID 15534133.
  3. ↑ Lemp MA, Nichols KK (2009). "Blepharitis in the United States 2009: a survey-based perspective on prevalence and treatment". Ocul Surf. 7 (2 Suppl): S1–S14. PMID 19383269.
  4. ↑ Beare JM (1969). "Blepharitis and related conditions". Proc R Soc Med. 62 (1): 5–7. PMC 2279072. PMID 4236660.
  5. ↑ Bowman RW, Dougherty JM, McCulley JP (1987). "Chronic blepharitis and dry eyes". Int Ophthalmol Clin. 27 (1): 27–35. PMID 3818198.
  6. ↑ Blepharitis. American Academy of Ophthalmology/eyewiki (2014) http://eyewiki.org/Blepharitis Accessed on July 14, 2016
  7. ↑ Leibowitz HM (2000). "The red eye". N Engl J Med. 343 (5): 345–51. doi:10.1056/NEJM200008033430507. PMID 10922425.
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