Syphilis MRI: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
m (Bot: Removing from Primary care)
 
(17 intermediate revisions by 6 users not shown)
Line 3: Line 3:
{{Syphilis}}
{{Syphilis}}
==Overview==
==Overview==
MRI scan is not diagnostic of syphilis. However, non-specific MRI findings may demonstrate complications of syphilis including neurological, gastrointestinal, and bone findings.<ref name="pmid17628376">{{cite journal| author=Peng F, Hu X, Zhong X, Wei Q, Jiang Y, Bao J et al.| title=CT and MR findings in HIV-negative neurosyphilis. | journal=Eur J Radiol | year= 2008 | volume= 66 | issue= 1 | pages= 1-6 | pmid=17628376 | doi=10.1016/j.ejrad.2007.05.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17628376  }} </ref><ref name="pmid7611026">{{cite journal| author=Brightbill TC, Ihmeidan IH, Post MJ, Berger JR, Katz DA| title=Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings. | journal=AJNR Am J Neuroradiol | year= 1995 | volume= 16 | issue= 4 | pages= 703-11 | pmid=7611026 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7611026  }} </ref><ref name="pmid22994551">{{cite journal| author=Mehrabian S, Raycheva M, Traykova M, Stankova T, Penev L, Grigorova O et al.| title=Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging. | journal=BMC Neurol | year= 2012 | volume= 12 | issue=  | pages= 96 | pmid=22994551 | doi=10.1186/1471-2377-12-96 | pmc=3517431 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22994551  }} </ref><ref name="pmid19412521">{{cite journal| author=Jeong YM, Hwang HY, Kim HS| title=MRI of neurosyphilis presenting as mesiotemporal abnormalities: a case report. | journal=Korean J Radiol | year= 2009 | volume= 10 | issue= 3 | pages= 310-2 | pmid=19412521 | doi=10.3348/kjr.2009.10.3.310 | pmc=2672188 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19412521  }} </ref><ref name="pmid11264042">{{cite journal| author=Szilak I, Marty F, Helft J, Soeiro R| title=Neurosyphilis presenting as herpes simplex encephalitis. | journal=Clin Infect Dis | year= 2001 | volume= 32 | issue= 7 | pages= 1108-9 | pmid=11264042 | doi=10.1086/319598 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11264042  }} </ref><ref name="pmid11156776">{{cite journal| author=Bash S, Hathout GM, Cohen S| title=Mesiotemporal T2-weighted hyperintensity: neurosyphilis mimicking herpes encephalitis. | journal=AJNR Am J Neuroradiol | year= 2001 | volume= 22 | issue= 2 | pages= 314-6 | pmid=11156776 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11156776  }} </ref><ref name="pmid23479472">{{cite journal| author=Agayeva N, Karli-Oguz K, Saka E| title=Teaching NeuroImages: a neurosyphilis case presenting with atypical neuroradiologic findings. | journal=Neurology | year= 2013 | volume= 80 | issue= 11 | pages= e119 | pmid=23479472 | doi=10.1212/WNL.0b013e318287280b | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23479472  }} </ref><ref name="pmid24261864">{{cite journal| author=Khamaysi Z, Bergman R, Telman G, Goldsher D| title=Clinical and imaging findings in patients with neurosyphilis: a study of a cohort and review of the literature. | journal=Int J Dermatol | year= 2014 | volume= 53 | issue= 7 | pages= 812-9 | pmid=24261864 | doi=10.1111/ijd.12095 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24261864  }} </ref><ref name="pmid:    22330117">{{cite journal| author=Pandey S| title=Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. | journal=J Spinal Cord Med | year= 2011 | volume= 34 | issue= 6 | pages= 609-11 | pmid=:    22330117 | doi=10.1179/2045772311Y.0000000041 | pmc=3237288 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22330117  }} </ref><ref name="pmid17297001">{{cite journal| author=Huang I, Leach JL, Fichtenbaum CJ, Narayan RK| title=Osteomyelitis of the skull in early-acquired syphilis: evaluation by MR imaging and CT. | journal=AJNR Am J Neuroradiol | year= 2007 | volume= 28 | issue= 2 | pages= 307-8 | pmid=17297001 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17297001  }} </ref><ref name="pmid20191023">{{cite journal| author=Cha JM, Choi SI, Lee JI| title=Rectal syphilis mimicking rectal cancer. | journal=Yonsei Med J | year= 2010 | volume= 51 | issue= 2 | pages= 276-8 | pmid=20191023 | doi=10.3349/ymj.2010.51.2.276 | pmc=2824876 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20191023  }} </ref><ref name="pmid:22330117">{{cite journal| author=Pandey S| title=Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. | journal=J Spinal Cord Med | year= 2011 | volume= 34 | issue= 6 | pages= 609-11 | pmid=:    22330117 | doi=10.1179/2045772311Y.0000000041 | pmc=3237288 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22330117  }} </ref>


==MRI==
==MRI==
MRI scan is not diagnostic of syphilis. However, non-specific MRI findings may demonstrate complications of syphilis including neurological, gastrointestinal, and bone findings:<ref name="pmid17628376">{{cite journal| author=Peng F, Hu X, Zhong X, Wei Q, Jiang Y, Bao J et al.| title=CT and MR findings in HIV-negative neurosyphilis. | journal=Eur J Radiol | year= 2008 | volume= 66 | issue= 1 | pages= 1-6 | pmid=17628376 | doi=10.1016/j.ejrad.2007.05.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17628376  }} </ref><ref name="pmid7611026">{{cite journal| author=Brightbill TC, Ihmeidan IH, Post MJ, Berger JR, Katz DA| title=Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings. | journal=AJNR Am J Neuroradiol | year= 1995 | volume= 16 | issue= 4 | pages= 703-11 | pmid=7611026 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7611026  }} </ref><ref name="pmid22994551">{{cite journal| author=Mehrabian S, Raycheva M, Traykova M, Stankova T, Penev L, Grigorova O et al.| title=Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging. | journal=BMC Neurol | year= 2012 | volume= 12 | issue=  | pages= 96 | pmid=22994551 | doi=10.1186/1471-2377-12-96 | pmc=3517431 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22994551  }} </ref><ref name="pmid19412521">{{cite journal| author=Jeong YM, Hwang HY, Kim HS| title=MRI of neurosyphilis presenting as mesiotemporal abnormalities: a case report. | journal=Korean J Radiol | year= 2009 | volume= 10 | issue= 3 | pages= 310-2 | pmid=19412521 | doi=10.3348/kjr.2009.10.3.310 | pmc=2672188 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19412521  }} </ref><ref name="pmid11264042">{{cite journal| author=Szilak I, Marty F, Helft J, Soeiro R| title=Neurosyphilis presenting as herpes simplex encephalitis. | journal=Clin Infect Dis | year= 2001 | volume= 32 | issue= 7 | pages= 1108-9 | pmid=11264042 | doi=10.1086/319598 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11264042  }} </ref><ref name="pmid11156776">{{cite journal| author=Bash S, Hathout GM, Cohen S| title=Mesiotemporal T2-weighted hyperintensity: neurosyphilis mimicking herpes encephalitis. | journal=AJNR Am J Neuroradiol | year= 2001 | volume= 22 | issue= 2 | pages= 314-6 | pmid=11156776 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11156776  }} </ref><ref name="pmid23479472">{{cite journal| author=Agayeva N, Karli-Oguz K, Saka E| title=Teaching NeuroImages: a neurosyphilis case presenting with atypical neuroradiologic findings. | journal=Neurology | year= 2013 | volume= 80 | issue= 11 | pages= e119 | pmid=23479472 | doi=10.1212/WNL.0b013e318287280b | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23479472  }} </ref><ref name="pmid24261864">{{cite journal| author=Khamaysi Z, Bergman R, Telman G, Goldsher D| title=Clinical and imaging findings in patients with neurosyphilis: a study of a cohort and review of the literature. | journal=Int J Dermatol | year= 2014 | volume= 53 | issue= 7 | pages= 812-9 | pmid=24261864 | doi=10.1111/ijd.12095 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24261864  }} </ref><ref name="pmid:    22330117">{{cite journal| author=Pandey S| title=Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. | journal=J Spinal Cord Med | year= 2011 | volume= 34 | issue= 6 | pages= 609-11 | pmid=:    22330117 | doi=10.1179/2045772311Y.0000000041 | pmc=3237288 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22330117  }} </ref><ref name="pmid17297001">{{cite journal| author=Huang I, Leach JL, Fichtenbaum CJ, Narayan RK| title=Osteomyelitis of the skull in early-acquired syphilis: evaluation by MR imaging and CT. | journal=AJNR Am J Neuroradiol | year= 2007 | volume= 28 | issue= 2 | pages= 307-8 | pmid=17297001 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17297001  }} </ref><ref name="pmid20191023">{{cite journal| author=Cha JM, Choi SI, Lee JI| title=Rectal syphilis mimicking rectal cancer. | journal=Yonsei Med J | year= 2010 | volume= 51 | issue= 2 | pages= 276-8 | pmid=20191023 | doi=10.3349/ymj.2010.51.2.276 | pmc=2824876 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20191023  }} </ref>
===Neurosyphilis===
MRI may help diagnose complications of syphilis such as neurosyphilis. High intensity T2 MRI brain and spinal cord may indicate the following findings:<ref name="pmid17628376">{{cite journal| author=Peng F, Hu X, Zhong X, Wei Q, Jiang Y, Bao J et al.| title=CT and MR findings in HIV-negative neurosyphilis. | journal=Eur J Radiol | year= 2008 | volume= 66 | issue= 1 | pages= 1-6 | pmid=17628376 | doi=10.1016/j.ejrad.2007.05.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17628376  }} </ref><ref name="pmid7611026">{{cite journal| author=Brightbill TC, Ihmeidan IH, Post MJ, Berger JR, Katz DA| title=Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings. | journal=AJNR Am J Neuroradiol | year= 1995 | volume= 16 | issue= 4 | pages= 703-11 | pmid=7611026 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7611026  }} </ref><ref name="pmid22994551">{{cite journal| author=Mehrabian S, Raycheva M, Traykova M, Stankova T, Penev L, Grigorova O et al.| title=Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging. | journal=BMC Neurol | year= 2012 | volume= 12 | issue=  | pages= 96 | pmid=22994551 | doi=10.1186/1471-2377-12-96 | pmc=3517431 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22994551  }} </ref><ref name="pmid19412521">{{cite journal| author=Jeong YM, Hwang HY, Kim HS| title=MRI of neurosyphilis presenting as mesiotemporal abnormalities: a case report. | journal=Korean J Radiol | year= 2009 | volume= 10 | issue= 3 | pages= 310-2 | pmid=19412521 | doi=10.3348/kjr.2009.10.3.310 | pmc=2672188 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19412521  }} </ref><ref name="pmid:    22330117">{{cite journal| author=Pandey S| title=Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. | journal=J Spinal Cord Med | year= 2011 | volume= 34 | issue= 6 | pages= 609-11 | pmid=:    22330117 | doi=10.1179/2045772311Y.0000000041 | pmc=3237288 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22330117  }} </ref>   
*Non specific [[white matter]] lesions (cerebral gummas or [[arteritis]])<ref name="pmid7611026">{{cite journal| author=Brightbill TC, Ihmeidan IH, Post MJ, Berger JR, Katz DA| title=Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings. | journal=AJNR Am J Neuroradiol | year= 1995 | volume= 16 | issue= 4 | pages= 703-11 | pmid=7611026 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7611026  }} </ref>
*Hyperintensity in mesiotemporal lobes<ref name="pmid19412521">{{cite journal| author=Jeong YM, Hwang HY, Kim HS| title=MRI of neurosyphilis presenting as mesiotemporal abnormalities: a case report. | journal=Korean J Radiol | year= 2009 | volume= 10 | issue= 3 | pages= 310-2 | pmid=19412521 | doi=10.3348/kjr.2009.10.3.310 | pmc=2672188 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19412521  }} </ref><ref name="pmid11264042">{{cite journal| author=Szilak I, Marty F, Helft J, Soeiro R| title=Neurosyphilis presenting as herpes simplex encephalitis. | journal=Clin Infect Dis | year= 2001 | volume= 32 | issue= 7 | pages= 1108-9 | pmid=11264042 | doi=10.1086/319598 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11264042  }} </ref>
*Cortical [[atrophy]] (general [[paresis]])<ref name="pmid17628376">{{cite journal| author=Peng F, Hu X, Zhong X, Wei Q, Jiang Y, Bao J et al.| title=CT and MR findings in HIV-negative neurosyphilis. | journal=Eur J Radiol | year= 2008 | volume= 66 | issue= 1 | pages= 1-6 | pmid=17628376 | doi=10.1016/j.ejrad.2007.05.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17628376  }} </ref>
*[[Cerebral infarction]]
*Hippocampal [[atrophy]] (mimicking [[alzheimer's disease]])<ref name="pmid22994551">{{cite journal| author=Mehrabian S, Raycheva M, Traykova M, Stankova T, Penev L, Grigorova O et al.| title=Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging. | journal=BMC Neurol | year= 2012 | volume= 12 | issue=  | pages= 96 | pmid=22994551 | doi=10.1186/1471-2377-12-96 | pmc=3517431 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22994551  }} </ref>
*Hyperintensities in multiple cortical areas and [[thalami]] <ref name="pmid23479472">{{cite journal| author=Agayeva N, Karli-Oguz K, Saka E| title=Teaching NeuroImages: a neurosyphilis case presenting with atypical neuroradiologic findings. | journal=Neurology | year= 2013 | volume= 80 | issue= 11 | pages= e119 | pmid=23479472 | doi=10.1212/WNL.0b013e318287280b | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23479472  }} </ref>
*Intramedullary hyperintensity and spinal cord atrophy<ref name="pmid:22330117">{{cite journal| author=Pandey S| title=Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. | journal=J Spinal Cord Med | year= 2011 | volume= 34 | issue= 6 | pages= 609-11 | pmid=:    22330117 | doi=10.1179/2045772311Y.0000000041 | pmc=3237288 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22330117  }} </ref>
===Bone===
*Small [[Tibia|tibial]] and [[Fibula|fibular]] nodular hyperintense lesions<ref name="pmid19795120">{{cite journal| author=Naraghi AM, Salonen DC, Bloom JA, Becker EJ| title=Magnetic resonance imaging features of osseous manifestations of early acquired syphilis. | journal=Skeletal Radiol | year= 2010 | volume= 39 | issue= 3 | pages= 305-9 | pmid=19795120 | doi=10.1007/s00256-009-0806-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19795120  }} </ref>
===Skull===
*T2W lesions in the skull showing hyperintensity<ref name="pmid17297001">{{cite journal| author=Huang I, Leach JL, Fichtenbaum CJ, Narayan RK| title=Osteomyelitis of the skull in early-acquired syphilis: evaluation by MR imaging and CT. | journal=AJNR Am J Neuroradiol | year= 2007 | volume= 28 | issue= 2 | pages= 307-8 | pmid=17297001 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17297001  }} </ref>
===Rectal===
*T2W MRI images showing hyperintense thickening of rectal wall (mimicking [[rectal cancer]])<ref name="pmid20191023">{{cite journal| author=Cha JM, Choi SI, Lee JI| title=Rectal syphilis mimicking rectal cancer. | journal=Yonsei Med J | year= 2010 | volume= 51 | issue= 2 | pages= 276-8 | pmid=20191023 | doi=10.3349/ymj.2010.51.2.276 | pmc=2824876 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20191023  }} </ref>


==References==
==References==
Line 11: Line 30:
{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}


[[Category:Gynecology]]
[[Category:Gynecology]]
[[Category:Emergency mdicine]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Primary care]]
[[Category:Urology]]
[[Category:Neurology]]

Latest revision as of 00:23, 30 July 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Sexually transmitted diseases Main Page

Syphilis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Syphilis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Primary and Secondary Syphilis
Latent Syphilis
Tertiary Syphilis
Neurosyphilis
HIV-Infected Patients
Pregnancy
Management of Sexual Partners

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Syphilis MRI On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Syphilis MRI

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Syphilis MRI

CDC on Syphilis MRI

Syphilis MRI in the news

Blogs on Syphilis MRI

Directions to Hospitals Treating Syphilis

Risk calculators and risk factors for Syphilis MRI

Overview

MRI scan is not diagnostic of syphilis. However, non-specific MRI findings may demonstrate complications of syphilis including neurological, gastrointestinal, and bone findings.[1][2][3][4][5][6][7][8][9][10][11][12]

MRI

MRI scan is not diagnostic of syphilis. However, non-specific MRI findings may demonstrate complications of syphilis including neurological, gastrointestinal, and bone findings:[1][2][3][4][5][6][7][8][9][10][11]

Neurosyphilis

MRI may help diagnose complications of syphilis such as neurosyphilis. High intensity T2 MRI brain and spinal cord may indicate the following findings:[1][2][3][4][9]

Bone

Skull

  • T2W lesions in the skull showing hyperintensity[10]

Rectal

  • T2W MRI images showing hyperintense thickening of rectal wall (mimicking rectal cancer)[11]

References

  1. ↑ 1.0 1.1 1.2 1.3 Peng F, Hu X, Zhong X, Wei Q, Jiang Y, Bao J; et al. (2008). "CT and MR findings in HIV-negative neurosyphilis". Eur J Radiol. 66 (1): 1–6. doi:10.1016/j.ejrad.2007.05.018. PMID 17628376.
  2. ↑ 2.0 2.1 2.2 2.3 Brightbill TC, Ihmeidan IH, Post MJ, Berger JR, Katz DA (1995). "Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings". AJNR Am J Neuroradiol. 16 (4): 703–11. PMID 7611026.
  3. ↑ 3.0 3.1 3.2 3.3 Mehrabian S, Raycheva M, Traykova M, Stankova T, Penev L, Grigorova O; et al. (2012). "Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging". BMC Neurol. 12: 96. doi:10.1186/1471-2377-12-96. PMC 3517431. PMID 22994551.
  4. ↑ 4.0 4.1 4.2 4.3 Jeong YM, Hwang HY, Kim HS (2009). "MRI of neurosyphilis presenting as mesiotemporal abnormalities: a case report". Korean J Radiol. 10 (3): 310–2. doi:10.3348/kjr.2009.10.3.310. PMC 2672188. PMID 19412521.
  5. ↑ 5.0 5.1 5.2 Szilak I, Marty F, Helft J, Soeiro R (2001). "Neurosyphilis presenting as herpes simplex encephalitis". Clin Infect Dis. 32 (7): 1108–9. doi:10.1086/319598. PMID 11264042.
  6. ↑ 6.0 6.1 Bash S, Hathout GM, Cohen S (2001). "Mesiotemporal T2-weighted hyperintensity: neurosyphilis mimicking herpes encephalitis". AJNR Am J Neuroradiol. 22 (2): 314–6. PMID 11156776.
  7. ↑ 7.0 7.1 7.2 Agayeva N, Karli-Oguz K, Saka E (2013). "Teaching NeuroImages: a neurosyphilis case presenting with atypical neuroradiologic findings". Neurology. 80 (11): e119. doi:10.1212/WNL.0b013e318287280b. PMID 23479472.
  8. ↑ 8.0 8.1 Khamaysi Z, Bergman R, Telman G, Goldsher D (2014). "Clinical and imaging findings in patients with neurosyphilis: a study of a cohort and review of the literature". Int J Dermatol. 53 (7): 812–9. doi:10.1111/ijd.12095. PMID 24261864.
  9. ↑ 9.0 9.1 9.2 Pandey S (2011). "Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis". J Spinal Cord Med. 34 (6): 609–11. doi:10.1179/2045772311Y.0000000041. PMC 3237288. PMID 22330117 : 22330117 Check |pmid= value (help).
  10. ↑ 10.0 10.1 10.2 Huang I, Leach JL, Fichtenbaum CJ, Narayan RK (2007). "Osteomyelitis of the skull in early-acquired syphilis: evaluation by MR imaging and CT". AJNR Am J Neuroradiol. 28 (2): 307–8. PMID 17297001.
  11. ↑ 11.0 11.1 11.2 Cha JM, Choi SI, Lee JI (2010). "Rectal syphilis mimicking rectal cancer". Yonsei Med J. 51 (2): 276–8. doi:10.3349/ymj.2010.51.2.276. PMC 2824876. PMID 20191023.
  12. ↑ 12.0 12.1 Pandey S (2011). "Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis". J Spinal Cord Med. 34 (6): 609–11. doi:10.1179/2045772311Y.0000000041. PMC 3237288. PMID 22330117 : 22330117 Check |pmid= value (help).
  13. ↑ Naraghi AM, Salonen DC, Bloom JA, Becker EJ (2010). "Magnetic resonance imaging features of osseous manifestations of early acquired syphilis". Skeletal Radiol. 39 (3): 305–9. doi:10.1007/s00256-009-0806-7. PMID 19795120.


Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=Syphilis_MRI&oldid=1643803"