Syphilis other diagnostic studies: Difference between revisions
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{{CMG}}{{AE}}{{AA}} | {{CMG}}; {{AE}} {{AA}} | ||
{{Syphilis}} | {{Syphilis}} | ||
==Overview== | ==Overview== | ||
Other diagnostic studies which may help diagnose complications of syphilis are CSF examination | Other diagnostic studies which may help diagnose complications of syphilis are CSF examination, screening tests for other [[STI|STIs]] such as [[HIV]], [[chlamydia]], [[gonorrhea]], and biopsy.<ref name=CDC2016>http://www.cdc.gov/std/tg2015/syphilis.htm accessed on September 28, 2016</ref><ref name="pmid10772085">{{cite journal| author=Luger AF, Schmidt BL, Kaulich M| title=Significance of laboratory findings for the diagnosis of neurosyphilis. | journal=Int J STD AIDS | year= 2000 | volume= 11 | issue= 4 | pages= 224-34 | pmid=10772085 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10772085 }} </ref> | ||
== | ==Other Diagnostic Studies== | ||
Other diagnostic studies which may help diagnose complications of syphilis are:<ref name=CDC2016>http://www.cdc.gov/std/tg2015/syphilis.htm accessed on September 28, 2016</ref><ref name="pmid10772085">{{cite journal| author=Luger AF, Schmidt BL, Kaulich M| title=Significance of laboratory findings for the diagnosis of neurosyphilis. | journal=Int J STD AIDS | year= 2000 | volume= 11 | issue= 4 | pages= 224-34 | pmid=10772085 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10772085 }} </ref> | Other diagnostic studies which may help diagnose complications of syphilis are:<ref name=CDC2016>http://www.cdc.gov/std/tg2015/syphilis.htm accessed on September 28, 2016</ref><ref name="pmid10772085">{{cite journal| author=Luger AF, Schmidt BL, Kaulich M| title=Significance of laboratory findings for the diagnosis of neurosyphilis. | journal=Int J STD AIDS | year= 2000 | volume= 11 | issue= 4 | pages= 224-34 | pmid=10772085 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10772085 }} </ref> | ||
===CSF examination | ===CSF examination === | ||
*May help to diagnose neurosyphilis | *May help to diagnose neurosyphilis | ||
* | *Includes CSF cell count or protein and a reactive CSF-[[VDRL]] or CSF [[FTA-ABS]] test | ||
*CSF-VDRL is highly specific but insensitive | *CSF-[[VDRL]] is highly specific but insensitive | ||
*CSF FTA-ABS test is less specific for [[neurosyphilis]] than the CSF- | *CSF [[FTA-ABS]] test is less specific for [[neurosyphilis]] than the CSF-VDRL but is highly sensitive | ||
===Screening tests for other STIs=== | ===Screening tests for other STIs=== | ||
* | *Includes [[HIV]], [[chlamydia]], and [[gonorrhea]] | ||
===Biopsy=== | ===Biopsy=== | ||
Biopsy may be considered if clinical findings | *[[Biopsy]] may be considered if clinical findings do not correlate with negative serological tests and there is a strong index of suspicion for syphilis. | ||
==References== | ==References== | ||
{{reflist|2}} | |||
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Latest revision as of 00:23, 30 July 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]
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Overview
Other diagnostic studies which may help diagnose complications of syphilis are CSF examination, screening tests for other STIs such as HIV, chlamydia, gonorrhea, and biopsy.[1][2]
Other Diagnostic Studies
Other diagnostic studies which may help diagnose complications of syphilis are:[1][2]
CSF examination
- May help to diagnose neurosyphilis
- Includes CSF cell count or protein and a reactive CSF-VDRL or CSF FTA-ABS test
- CSF-VDRL is highly specific but insensitive
- CSF FTA-ABS test is less specific for neurosyphilis than the CSF-VDRL but is highly sensitive
Screening tests for other STIs
Biopsy
- Biopsy may be considered if clinical findings do not correlate with negative serological tests and there is a strong index of suspicion for syphilis.
References
- ↑ 1.0 1.1 http://www.cdc.gov/std/tg2015/syphilis.htm accessed on September 28, 2016
- ↑ 2.0 2.1 Luger AF, Schmidt BL, Kaulich M (2000). "Significance of laboratory findings for the diagnosis of neurosyphilis". Int J STD AIDS. 11 (4): 224–34. PMID 10772085.