Pancreatic insufficiency: Difference between revisions
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| '''Gastroenterologic''' | | '''Gastroenterologic''' | ||
|bgcolor="Beige"| [[Chronic pancreatitis]], [[Cystic fibrosis]], [[Diabetic gastroparesis]], [[Gallstones]], [[Hemochromatosis]] | |bgcolor="Beige"| [[Bowel resection]], [[Celiac disease]], [[Chronic pancreatitis]], [[Cystic fibrosis]], [[Diabetic gastroparesis]], [[Gallstones]], [[Hemochromatosis]] , [[Short bowel syndrome]] | ||
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| '''Iatrogenic''' | | '''Iatrogenic''' | ||
|bgcolor="Beige"| [[ | |bgcolor="Beige"| [[Bowel resection]], [[Gastrectomy]] , [[Pancreatectomy]] | ||
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| '''Nutritional/Metabolic''' | | '''Nutritional/Metabolic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Malnutrition]] | ||
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| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| [[Chronic alcoholism]], [[Pancreatic cyst]], [[Pancreatic duct]] | |bgcolor="Beige"| [[Chronic alcoholism]], [[Pancreatic cyst]], [[Cholestasis|Pancreatic duct obstruction]], [[Pancreatic pseudocyst]] | ||
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===Causes in Alphabetical Order=== | ===Causes in Alphabetical Order=== | ||
{{columns-list | {{columns-list| | ||
*[[Acute intermittent porphyria]] | *[[Acute intermittent porphyria]] | ||
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*[[Ataxia telangiectasia]] | *[[Ataxia telangiectasia]] | ||
*[[Autoimmune lymphoproliferative syndrome]] | *[[Autoimmune lymphoproliferative syndrome]] | ||
*[[Bowel resection]] | |||
*[[Celiac disease]] | |||
*[[Chronic alcoholism]] | *[[Chronic alcoholism]] | ||
*[[Chronic pancreatitis]] | *[[Chronic pancreatitis]] | ||
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*[[Diabetic gastroparesis]] | *[[Diabetic gastroparesis]] | ||
*[[Gallstones]] | *[[Gallstones]] | ||
*[[Gastrectomy]] | |||
*[[Gestational diabetes]] | *[[Gestational diabetes]] | ||
*[[Havlikova syndrome]] | *[[Havlikova syndrome]] | ||
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*[[Juvenile tropical pancreatitis syndrome]] | *[[Juvenile tropical pancreatitis syndrome]] | ||
*[[Lupus]] | *[[Lupus]] | ||
*[[Malnutrition]] | |||
*[[Mumps]] | *[[Mumps]] | ||
*[[Pancreatectomy]] | *[[Pancreatectomy]] | ||
* [[Pancreas divisum]] | |||
*[[Pancreatic agenesis]] | *[[Pancreatic agenesis]] | ||
*[[Pancreatic cancer]] | *[[Pancreatic cancer]] | ||
*[[Pancreatic cyst]] | *[[Pancreatic cyst]] | ||
*[[Pancreatic duct]] | *[[Cholestasis|Pancreatic duct obstruction]] | ||
*[[Pancreatic pseudocyst]] | *[[Pancreatic pseudocyst]] | ||
*[[Pearson syndrome]] | *[[Pearson syndrome]] | ||
*[[Polyglandular autoimmune syndrome]] | *[[Polyglandular autoimmune syndrome]] | ||
*[[Short bowel syndrome]] | |||
*[[Shwachman-Diamond syndrome]] | *[[Shwachman-Diamond syndrome]] | ||
*[[Situs inversus totalis with cystic dysplasia of pancreas]] | *[[Situs inversus totalis with cystic dysplasia of pancreas]] | ||
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== Differential Diagnosis of Causes of {{PAGENAME}}== | == Differential Diagnosis of Causes of {{PAGENAME}}== | ||
{{columns-list | {{columns-list| | ||
*[[Chronic alcoholism]] | *[[Chronic alcoholism]] | ||
*[[Congenital pancreatic dysfunction]] | *[[Congenital pancreatic dysfunction]] | ||
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==Treatment== | ==Treatment== | ||
Often | Often pancreatic insufficiency is treated with Pancreatic Enzyme Products (PEPs), such as [[pancrelipase]], that are used to breakdown fats ([[lipases]]), proteins ([[proteases]]) and carbohydrates ([[amylases]]) into units that can be digested by those with pancreatic insufficiency. <ref>[http://www.fda.gov/cder/otcmonographs/category_sort/pancreatic_insufficiency.htm FDA rulemaking history of OTC EPI drug products]</ref> | ||
== References == | == References == | ||
Latest revision as of 22:18, 10 January 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]
Synonyms and keywords: Exocrine pancreatic insufficiency
Overview
Pancreatic insufficiency is characterized by deficiency of the exocrine pancreatic enzymes, resulting in the inability to digest food properly, or maldigestion.
Causes
Common Causes
- Chronic alcoholism
- Chronic pancreatitis
- Cystic fibrosis
- Gall stones
- Gastrectomy
- Shwachman-Diamond syndrome
- Zollinger-Ellison syndrome
Causes by Organ System
Causes in Alphabetical Order
- Acute intermittent porphyria
- Alagille syndrome
- Alpha-1 antitrypsin deficiency
- Annular pancreas
- Ataxia telangiectasia
- Autoimmune lymphoproliferative syndrome
- Bowel resection
- Celiac disease
- Chronic alcoholism
- Chronic pancreatitis
- Congenital lipomatosis of pancreas
- Congenital pancreatic dysfunction
- Congenital partial lipodystrophy
- Cystic fibrosis
- Diabetic gastroparesis
- Gallstones
- Gastrectomy
- Gestational diabetes
- Havlikova syndrome
- Hemochromatosis
- Hereditary pancreatitis
- Homocystinuria
- Hyperparathyroidism
- Hypertriglyceridemia
- Idiopathic pancreatitis
- Johanson-Blizzard syndrome
- Juvenile tropical pancreatitis syndrome
- Lupus
- Malnutrition
- Mumps
- Pancreatectomy
- Pancreas divisum
- Pancreatic agenesis
- Pancreatic cancer
- Pancreatic cyst
- Pancreatic duct obstruction
- Pancreatic pseudocyst
- Pearson syndrome
- Polyglandular autoimmune syndrome
- Short bowel syndrome
- Shwachman-Diamond syndrome
- Situs inversus totalis with cystic dysplasia of pancreas
- Sjogren's syndrome
- Trauma
- Wolfram's disease
- Zollinger-Ellison syndrome
Diagnosis
History and Symptoms
Differential Diagnosis of Causes of Pancreatic insufficiency
Treatment
Often pancreatic insufficiency is treated with Pancreatic Enzyme Products (PEPs), such as pancrelipase, that are used to breakdown fats (lipases), proteins (proteases) and carbohydrates (amylases) into units that can be digested by those with pancreatic insufficiency. [1]
References