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'''For patient information, click [[Xyz (patient information)|here]]'''
{{Myoglobinuria}}
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  Caption = Model of helical domains in myoglobin. |
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{{SI}}
{{CMG}}; {{AE}} {{AKS}}; {{VSKP}}
{{CMG}}
 
 
==[[Myoglobinuria overview|Overview]]==
 
==[[Myoglobinuria historical perspective|Historical Perspective]]==


==Overview==
==[[Myoglobinuria classification|Classification]]==
Myoglobinuria is the presence of [[myoglobin]] in the urine, usually associated with [[rhabdomyolysis]] or muscle destruction. Myoglobin is present in [[muscle]] cells as a reserve of [[oxygen]].


==Pathophysiology==
==[[Myoglobinuria pathophysiology|Pathophysiology]]==
Under ideal situations myoglobin will be filtered and excreted with the urine, but if too much myoglobin is released into the circulation or in case of renal problems, it can occlude the renal filtration system leading to acute tubular necrosis and acute [[renal insufficiency]].
==Causes==
===Causes by Organ System===
===Causes in Alphabetical Order===
==Differential diagnosis of causes of myoglobinuria==
[[Physical trauma|Trauma]], vascular problems, [[venom]]s, certain drugs and other situations can destroy or damage the muscle, releasing myoglobin to the circulation and thus to the kidneys.


Miscellaneous syndromes
==[[Myoglobinuria causes|Causes]]==
* [[Rhabdomyolysis]]
* Meyer-Betz disease


Autosomal recessive conditions
==[[Myoglobinuria differential diagnosis|Differentiating Myoglobinuria from other Diseases]]==
* Glycogenosis type 5
* Phosphogylcerate mutase 2 deficiency


Cardiac and vascular conditions
==[[Myoglobinuria epidemiology and demographics|Epidemiology and Demographics]]==
* [[Myocarditis]]


Inflammatory conditions
==[[Myoglobinuria risk factors|Risk Factors]]==
* [[Myositis]]


Trauma, mechanical and physical conditions
==[[Myoglobinuria screening|Screening]]==
* [[Burns]]
* [[Crush syndrome]]


==Differentiating myoglobinuria from [[hemoglobinuria]]==
==[[Myoglobinuria natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
After centrifuge, the serum of myologinuria is clear, where the serum of hemoglobinuria after centrifuge is pink.


==External Links==
==Diagnosis==
* [http://www.neuro.wustl.edu/neuromuscular/msys/myoglob.html Overview] at wustl.edu
[[Myoglobinuria diagnostic study of choice|Diagnostic study of choice]] | [[Myoglobinuria history and symptoms|History and Symptoms]] | [[Myoglobinuria physical examination|Physical Examination]] | [[Myoglobinuria  laboratory findings|Laboratory Findings]] | [[Myoglobinuria electrocardiogram|Electrocardiogram]] | [[Myoglobinuria x ray|X-Ray Findings]] | [[Myoglobinuria echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Myoglobinuria CT scan|CT-Scan Findings]] | [[Myoglobinuria MRI|MRI Findings]] | [[Myoglobinuria other imaging findings|Other Imaging Findings]] | [[Myoglobinuria other diagnostic studies|Other Diagnostic Studies]]
{{Abnormal clinical and laboratory findings}}


==Treatment==
[[Myoglobinuria medical therapy|Medical Therapy]] | [[Myoglobinuria surgery|Surgery]] | [[Myoglobinuria primary prevention|Primary Prevention]] | [[Myoglobinuria  secondary prevention|Secondary Prevention]] | [[Myoglobinuria cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Myoglobinuria future or investigational therapies|Future or Investigational Therapies]]


{{WH}}
==Case Studies==
{{WS}}
[[Myoglobinuria case study one|Case #1]]


[[Category:Disease]]
[[Category: (name of the system)]]
[[Category:Blood tests]]
[[Category:Urine tests]]

Latest revision as of 20:04, 15 August 2018

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Myoglobinuria
Model of helical domains in myoglobin.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya Stevasarova, M.D.; Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]


Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Myoglobinuria from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT-Scan Findings | MRI Findings | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1