Sandbox:Microscopic hematuria: Difference between revisions

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http://www.jurology.com/article/S0022-5347(12)04958-0/pdf
== History and Symptoms ==
 
{| style="width:80%; height:100px" border="10"
== Definition ==
|style="height:100px"; style="width:15%" border="1" | '''CATEGORY'''
Microscopic hematuria is defined as the presence of three or greater red blood cells per high powered
|style="height:100px"; style="width:15%" border="1" | '''EXAMPLES'''
field on a properly collected urinary specimen in the absence of an obvious benign cause.<ref name="pmid23098784">Davis R, Jones JS, Barocas DA, Castle EP, Lang EK, Leveillee RJ et al. (2012) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=23098784 Diagnosis, evaluation and follow-up of asymptomatic microhematuria (AMH) in adults: AUA guideline.] ''J Urol'' 188 (6 Suppl):2473-81. [http://dx.doi.org/10.1016/j.juro.2012.09.078 DOI:10.1016/j.juro.2012.09.078] PMID: [https://pubmed.gov/23098784 23098784]</ref>
|style="height:100px"; style="width:70%" border="1" | '''COMMON CLINICAL PRESENTATION AND RISK FACTORS'''
 
|-
== Prevalence ==
| rowspan="6" style="width:15%" ; border="1" | {{Center|Neoplasm}}
The prevalence of microscopic hematuria varies depending on age, gender, frequency of testing, threshold used to define MH and presence of risk factors such as smoking.
|style="height:100px"; style="width:15%" border="1" | {{Center|Any}}
|style="height:100px"; style="width:70%" border="1" | Male gender, Age older than 35 years, Past or current smoking history, Occupational or other exposure to chemicals or dyes (benzenes or aromatic amines), Analgesic abuse, History of gross hematuria, History of urologic disorder or disease, History of Irritative voiding symptoms, History of pelvic irradiation, History of chronic urinary tract infection, Exposure to known carcinogenic agents or chemotherapy such as alkylating agents, History of chronic indwelling foreign body
|-
|style="height:100px"; style="width:15%" border="1" | {{Center|Bladder cancer}}
|style="height:100px"; style="width:70%" border="1" | Older age, male predominance, tobacco, occupational exposures, Irritative voiding symptoms
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Ureteral or renal pelvis cancer}}
|style="height:100px"; style="width:15%" border="1" | Family history of early colon cancers or upper tract tumors, flank pain
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Renal cortical tumor}}
|style="height:100px"; style="width:15%" border="1" | Family history of early kidney tumors, flank pain, flank mass
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Prostate cancer}}
|style="height:100px"; style="width:15%" border="1" | Older age, family history, African-American
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Urethral cancer}}
|style="height:100px"; style="width:15%" border="1" | Obstructive symptoms, pain, bloody discharge
|-
| rowspan="6" style="width:15%" ; border="1" | {{Center|Infection/inflammation}}
|style="height:100px"; style="width:15%" border="1" | {{Center| Any}}
|style="height:100px"; style="width:15%" border="1" | History of infection
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Cystitis}}
|style="height:100px"; style="width:15%" border="1" | Female predominance, dysuria
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Pyelonephritis}}
|style="height:100px"; style="width:15%" border="1" | Fever, flank pain, diabetes, female predominance
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Urethritis}}
|style="height:100px"; style="width:15%" border="1" | Exposure to sexually transmitted infections, urethral discharge, dysuria
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Tuberculosis}}
|style="height:100px"; style="width:15%" border="1" | Travel to endemic areas
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Schistosomiasis}}
|style="height:100px"; style="width:15%" border="1" | Travel to endemic areas
|-
| rowspan="2" style="width:15%" ; border="1" | {{Center|Calculus}}
|style="height:100px"; style="width:15%" border="1" | {{Center| Nephroureterolithiasis}}
|style="height:100px"; style="width:15%" border="1" | Flank pain, family history, prior stone
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| Bladder stones}}
|style="height:100px"; style="width:15%" border="1" | Bladder outlet obstruction
|-
|style="height:100px"; style="width:15%" border="1" | {{Center|Benign prostatic enlargement}}
|style="height:100px"; style="width:15%" border="1" |
|style="height:100px"; style="width:15%" border="1" | Male, older age, obstructive symptoms
|-
| rowspan="2" style="width:15%" ; border="1" | {{Center|Medical renal disease}}
|style="height:100px"; style="width:15%" border="1" | {{Center| Any}}
|style="height:100px"; style="width:15%" border="1" | Hypertension, azotemia, dysmorphic erythrocytes, cellular casts, proteinuria
|-
|style="height:100px"; style="width:15%" border="1" | {{Center| IgA nephropathy}}
|style="height:100px"; style="width:15%" border="1" | upper respiratory tract infection, gastroenteritis, synchronous association of pharyngitis, children
|-
| rowspan="5" style="width:15%" ; border="1" | {{Center|Congenital or acquired anatomic abnormality}}
|style="height:100px"; style="width:15%" border="1" |  Polycystic kidney disease
|style="height:100px"; style="width:15%" border="1" | Family history of renal cystic disease
|-
|Uretero-pelvic junction    obstruction
|History of UTI, stone, flank pain
|-
|Ureteral stricture
|History of surgery or radiation, flank pain, hydronephrosis; stranguria, spraying urine
|-
|Urethral diverticulum
|Discharge, dribbling, dyspareunia, history of UTI, female predominance
|-
|Fistula
|Pneumaturia, Fecaluria, abdominal pain, recurrent UTI, history of diverticulitis or colon cancer
|-
| rowspan="5" style="width:15%" ; border="1" | {{Center|Other}}
| style="width:15%" ; border="1" | {{Center| Exercise-induced hematuria}}
| style="width:15%" ; border="1" | Recent vigorous exercise
|-
| style="width:15%" ; border="1" | {{Center| Endometriosis}}
| style="width:15%" ; border="1" | Cyclic hematuria in a menstruating woman
|-
| style="width:15%" ; border="1" | {{Center| Hematologic or thrombotic disease}}
| style="width:15%" ; border="1" | Family history of personal history of bleeding or thrombosis
|-
| style="width:15%" ; border="1" | {{Center| Papillary necrosis}}
| style="width:15%" ; border="1" | African-American, sickle cell disease, diabetes, analgesic abuse
|-
| style="width:15%" ; border="1" | {{Center| Interstitial cystitis}}
| style="width:15%" ; border="1" | Voiding symptoms
|-|}

Latest revision as of 14:49, 14 December 2016

History and Symptoms

CATEGORY EXAMPLES COMMON CLINICAL PRESENTATION AND RISK FACTORS
Neoplasm
Any
Male gender, Age older than 35 years, Past or current smoking history, Occupational or other exposure to chemicals or dyes (benzenes or aromatic amines), Analgesic abuse, History of gross hematuria, History of urologic disorder or disease, History of Irritative voiding symptoms, History of pelvic irradiation, History of chronic urinary tract infection, Exposure to known carcinogenic agents or chemotherapy such as alkylating agents, History of chronic indwelling foreign body
Bladder cancer
Older age, male predominance, tobacco, occupational exposures, Irritative voiding symptoms
Ureteral or renal pelvis cancer
Family history of early colon cancers or upper tract tumors, flank pain
Renal cortical tumor
Family history of early kidney tumors, flank pain, flank mass
Prostate cancer
Older age, family history, African-American
Urethral cancer
Obstructive symptoms, pain, bloody discharge
Infection/inflammation
Any
History of infection
Cystitis
Female predominance, dysuria
Pyelonephritis
Fever, flank pain, diabetes, female predominance
Urethritis
Exposure to sexually transmitted infections, urethral discharge, dysuria
Tuberculosis
Travel to endemic areas
Schistosomiasis
Travel to endemic areas
Calculus
Nephroureterolithiasis
Flank pain, family history, prior stone
Bladder stones
Bladder outlet obstruction
Benign prostatic enlargement
Male, older age, obstructive symptoms
Medical renal disease
Any
Hypertension, azotemia, dysmorphic erythrocytes, cellular casts, proteinuria
IgA nephropathy
upper respiratory tract infection, gastroenteritis, synchronous association of pharyngitis, children
Congenital or acquired anatomic abnormality
Polycystic kidney disease Family history of renal cystic disease
Uretero-pelvic junction obstruction History of UTI, stone, flank pain
Ureteral stricture History of surgery or radiation, flank pain, hydronephrosis; stranguria, spraying urine
Urethral diverticulum Discharge, dribbling, dyspareunia, history of UTI, female predominance
Fistula Pneumaturia, Fecaluria, abdominal pain, recurrent UTI, history of diverticulitis or colon cancer
Other
Exercise-induced hematuria
Recent vigorous exercise
Endometriosis
Cyclic hematuria in a menstruating woman
Hematologic or thrombotic disease
Family history of personal history of bleeding or thrombosis
Papillary necrosis
African-American, sickle cell disease, diabetes, analgesic abuse
Interstitial cystitis
Voiding symptoms