Pyelonephritis cost-effectiveness of therapy: Difference between revisions
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{{Pyelonephritis}} | {{Pyelonephritis}} | ||
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==Overview== | ==Overview== | ||
According to an estimate the mean cost of diagnosing and managing a patient with [[urinary tract infection]] including pyelonephritis is more than 229 pounds per year. [[Hyaluronan]] therapy given long term cuts down the cost of multiple pretreatments as it prevents recurrence of a [[ | According to an estimate the mean cost of diagnosing and managing a patient with [[urinary tract infection]] including pyelonephritis is more than 229 pounds per year. [[Hyaluronan]] therapy given long term cuts down the cost of multiple pretreatments as it prevents recurrence of a [[urinary tract infection]].<ref name="pmid23921624">{{cite journal| author=Riedl C, Engelhardt P, Schwarz B| title=Treatment costs of bladder pain syndrome/interstitial cystitis in Austria: a pharmacoeconomic approach following current guidelines. | journal=Clin Drug Investig | year= 2013 | volume= 33 | issue= 10 | pages= 737-42 | pmid=23921624 | doi=10.1007/s40261-013-0119-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23921624 }} </ref><ref name="pmid23475540">{{cite journal| author=Ciani O, Grassi D, Tarricone R| title=An economic perspective on urinary tract infection: the "costs of resignation". | journal=Clin Drug Investig | year= 2013 | volume= 33 | issue= 4 | pages= 255-61 | pmid=23475540 | doi=10.1007/s40261-013-0069-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23475540 }} </ref> | ||
==Cost-effective | ==Cost Effectiveness of therapies== | ||
*[[Hyaluronan]] is very cost effective in the long run when compared with all alternative treatments, despite initial high costs.<ref name="pmid23921624">{{cite journal| author=Riedl C, Engelhardt P, Schwarz B| title=Treatment costs of bladder pain syndrome/interstitial cystitis in Austria: a pharmacoeconomic approach following current guidelines. | journal=Clin Drug Investig | year= 2013 | volume= 33 | issue= 10 | pages= 737-42 | pmid=23921624 | doi=10.1007/s40261-013-0119-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23921624 }} </ref> | |||
*[[Amoxicillin]] is almost two times cheaper than [[aminoglycosides]] when used in the treatment of uncomplicated [[cystitis]] and [[pyelonephritis]].<ref name="pmid23475540">{{cite journal| author=Ciani O, Grassi D, Tarricone R| title=An economic perspective on urinary tract infection: the "costs of resignation". | journal=Clin Drug Investig | year= 2013 | volume= 33 | issue= 4 | pages= 255-61 | pmid=23475540 | doi=10.1007/s40261-013-0069-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23475540 }} </ref> | |||
*First and Second generation [[cephalosporins]] are considered to be cost effective in treating lower urinary tract infections empirically.<ref name="pmid10911441">{{cite journal| author=Jakobi P, Goldstick O, Finkelstein R, Itzkovitz-Eldor J| title=[Empirical treatment of urinary tract infections in the delivery room--findings and desires]. | journal=Harefuah | year= 1998 | volume= 135 | issue= 9 | pages= 344-7, 408 | pmid=10911441 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10911441 }} </ref> | |||
*[[Gentamicin]] is suggested as an cost effective therapy for treatment of pyelonephritis during pregnancy.<ref name="pmid10911441">{{cite journal| author=Jakobi P, Goldstick O, Finkelstein R, Itzkovitz-Eldor J| title=[Empirical treatment of urinary tract infections in the delivery room--findings and desires]. | journal=Harefuah | year= 1998 | volume= 135 | issue= 9 | pages= 344-7, 408 | pmid=10911441 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10911441 }} </ref> | |||
*The use of [[fluoroquinolone]] and [[nitrofurantoin]] is not cost effective.<ref name="pmid11784218">{{cite journal| author=Huang ES, Stafford RS| title=National patterns in the treatment of urinary tract infections in women by ambulatory care physicians. | journal=Arch Intern Med | year= 2002 | volume= 162 | issue= 1 | pages= 41-7 | pmid=11784218 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11784218 }} </ref> | |||
==References== | ==References== | ||
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[[Category:Emergency mdicine]] | |||
[[Category:Disease]] | |||
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[[Category:Infectious disease]] | |||
[[Category:Neurology]] | |||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]
Overview
According to an estimate the mean cost of diagnosing and managing a patient with urinary tract infection including pyelonephritis is more than 229 pounds per year. Hyaluronan therapy given long term cuts down the cost of multiple pretreatments as it prevents recurrence of a urinary tract infection.[1][2]
Cost Effectiveness of therapies
- Hyaluronan is very cost effective in the long run when compared with all alternative treatments, despite initial high costs.[1]
- Amoxicillin is almost two times cheaper than aminoglycosides when used in the treatment of uncomplicated cystitis and pyelonephritis.[2]
- First and Second generation cephalosporins are considered to be cost effective in treating lower urinary tract infections empirically.[3]
- Gentamicin is suggested as an cost effective therapy for treatment of pyelonephritis during pregnancy.[3]
- The use of fluoroquinolone and nitrofurantoin is not cost effective.[4]
References
- ↑ 1.0 1.1 Riedl C, Engelhardt P, Schwarz B (2013). "Treatment costs of bladder pain syndrome/interstitial cystitis in Austria: a pharmacoeconomic approach following current guidelines". Clin Drug Investig. 33 (10): 737–42. doi:10.1007/s40261-013-0119-4. PMID 23921624.
- ↑ 2.0 2.1 Ciani O, Grassi D, Tarricone R (2013). "An economic perspective on urinary tract infection: the "costs of resignation"". Clin Drug Investig. 33 (4): 255–61. doi:10.1007/s40261-013-0069-x. PMID 23475540.
- ↑ 3.0 3.1 Jakobi P, Goldstick O, Finkelstein R, Itzkovitz-Eldor J (1998). "[Empirical treatment of urinary tract infections in the delivery room--findings and desires]". Harefuah. 135 (9): 344–7, 408. PMID 10911441.
- ↑ Huang ES, Stafford RS (2002). "National patterns in the treatment of urinary tract infections in women by ambulatory care physicians". Arch Intern Med. 162 (1): 41–7. PMID 11784218.